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Aortic Dissection in a Neonate Receiving Extracorporeal Life Support Therapy: A Case Report

Abstract Extracorporeal life support (ECLS) therapy is increasingly being used to support children with refractory cardiorespiratory failure, but its use is occasionally associated with complications. Neonatal aortic dissection in association..

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Management of cardiogenic shock: state-of-the-art

Abstract The management of cardiogenic shock is an ongoing challenge. Despite all efforts and tremendous use of resources, mortality remains high. Whilst reversing the underlying cause, restoring/maintaining organ perfusion and..

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Left Ventricular Unloading in Extracorporeal Membrane Oxygenation: A Clinical Perspective Derived from Basic Cardiovascular Physiology

Abstract Purpose of Review To present an abridged overview of the literature and pathophysiological background of adjunct interventional left ventricular unloading strategies during veno-arterial extracorporeal membrane oxygenation (V-A ECMO). From..

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The absolute lactate levels versus clearance for prognostication of post-cardiotomy patients on veno-arterial ECMO

Abstract Aims Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a life-saving procedure for supporting patients with cardiogenic shock after cardiac surgery. This work aimed to analyse the impact of changes in..

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10 Critical TOE Findings in Cardiogenic Shock: Essential Knowledge for Intensive Care

Introduction: Picture this: You're standing at the bedside of a critically ill patient in the ICU, their life hanging by a thread as cardiogenic shock takes hold. The monitors are..

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Protocolised Management of Cardiogenic Shock and Shock Teams: A Narrative Review

Abstract Despite advances in therapy, the incidence of cardiogenic shock continues to increase, with significant mortality that has improved minimally over time. Treatment options for cardiogenic shock are complex and..

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Are mechanical circulatory supports the forgotten aspect in the implementation of therapies for heart failure?

Abstract Heart failure (HF) is a frequent and severe condition. It is estimated that one in four patients will die within a year following hospitalization for acute decompensation, with significant..

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Pulse Pressure and Acute Brain Injury in Venoarterial Extracorporeal Membrane Oxygenation: An Extracorporeal Life Support Organization Registry Analysis

Abstract Low pulse pressure (PP) in venoarterial-extracorporeal membrane oxygenation (VA-ECMO) is a marker of cardiac dysfunction and has been associated with acute brain injury (ABI) as continuous-flow centrifugal pump may..

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The American Association for Thoracic Surgery (AATS) 2024 expert consensus document: Management of neonates and infants with Ebstein anomaly

Abstract Objectives Symptomatic neonates and infants with Ebstein anomaly (EA) require complex management. A group of experts was commissioned by the American Association for Thoracic Surgery to provide a framework..

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Extracorporeal Life Support in Cardiogenic Shock Complicating Acute Myocardial Infarction

Abstract Despite multimodal treatment of patients with  (CS) complicating  (AMI), the outcome remains poor. Large retrospective analyses and animal models suggest that  (ECLS) in CS-complicating AMI improves outcome . However, to date, no  assessing the..

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Venoarterial Extracorporeal Membrane Oxygenation for Cardiopulmonary Support: Insights From a German Registry

Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) support is a lifesaving tool in cardiovascular care, providing excellent hemodynamic assistance for numerous indications, such as cardiogenic shock or periprocedural support in patients..

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Extracorporeal life support during cardiac arrest and cardiogenic shock: a systematic review and meta-analysis

Abstract Purpose Veno-arterial extracorporeal life support (ECLS) is increasingly used in patients during cardiac arrest and cardiogenic shock, to support both cardiac and pulmonary function. We performed a systematic review..

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Unloading in cardiogenic shock: the rationale and current evidence

Abstract Purpose of review  Discussing the rationale and current evidence for left ventricular unloading in cardiogenic shock. Recent findings  Microaxial flow pumps (MFP) and intra-aortic balloon pumps (IABP) augment cardiac..

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Design and principle of operation of the HeartMate PHP (percutaneous heart pump)

Abstract The HeartMate PHP (percutaneous heart pump) is a second-generation transcatheter axial flow circulatory support system. The collapsible catheter pump is inserted through a 14 Fr sheath, deployed across the..

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Routine venoarterial extracorporeal membrane oxygenation for acute myocardial infarction-related cardiogenic shock: what we know and don’t know

Abstract Acute myocardial infarction-related cardiogenic shock (AMI-CS) carries a dismal prognosis. Short-term mortality is in the range of 40–50% []. Until recently, only treatment of the culprit lesion by percutaneous..

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Step by step daily management of short-term mechanical circulatory support for cardiogenic shock in adults in the intensive cardiac care…

Abstract The use of mechanical circulatory support using percutaneous ventricular assist devices (pVAD) has increased rapidly during the last decade without substantial new evidence for their effect on outcome. In..

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Joint EAPCI/ACVC expert consensus document on percutaneous ventricular assist devices

Abstract There has been a significant increase in the use of short-term percutaneous ventricular assist devices (pVADs) as acute circulatory support in cardiogenic shock and to provide haemodynamic support during..

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Features and outcomes of female and male patients requiring postcardiotomy extracorporeal life support

Abstract Objectives Although cardiogenic shock requiring extracorporeal life support after cardiac surgery is associated with high mortality, the impact of sex on outcomes of postcardiotomy extracorporeal life support remains unclear..

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Sex differences in treatments and outcomes of patients with cardiogenic shock: a systematic review and epidemiological meta-analysis

Abstract Background Women are at higher risk of mortality from many acute cardiovascular conditions, but studies have demonstrated differing findings regarding the mortality of cardiogenic shock in women and men...

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Criteria for Defining Stages of Cardiogenic Shock Severity

Abstract Background Risk-stratifying patients with  (CS) is a major unmet need. The recently proposed Society for Cardiovascular  and Interventions (SCAI) staging system for CS severity lacks uniform criteria defining each stage. Objectives..

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Comparing Outcomes of Post-Cardiotomy Cardiogenic Shock Patients: On-Site Cannulation vs. Retrieval for V-A ECMO Support

Abstract Background:    Post-cardiotomy cardiogenic shock (PCCS) remains a life-threatening complication after cardiac surgery. Extracorporeal membrane oxygenation (ECMO) represents the mainstay of mechanical circulatory support for PCCS; however, its availability..

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Venoarterial extracorporeal membrane oxygenation in immunocompromised patients with cardiogenic shock: a cohort study and propensity-weighted analysis

Abstract Purpose: The outcomes of immunocompromised patients with cardiogenic shock treated with venoarterial extra‑corporeal membrane oxygenation (VA‑ECMO) are seldom documented, making ECMO candidacy decisions challeng‑ing. This study aims (1) to..

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Critical insights into venoarterial extracorporeal membrane oxygenation outcomes in immunocompromised patients: addressing uncertainties in cause of death and treatment strategies

Abstract In a recent issue of Intensive Care Medicine, we read with great interest the article by Moyon et al. [1] who retro-spectively studied the outcomes of immunocompromised patients with..

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Protected cardiac surgery: strategic mechanical circulatory support to improve postcardiotomy mortality

Abstract Purpose of review  To examine the evolving landscape of cardiac surgery, focusing on the increasing complexity of patients and the role of mechanical circulatory support (MCS) in managing perioperative..

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Validation of predictive models for 90-day survival in immunocompromised patients with cardiogenic shock on venoarterial extracorporeal membrane oxygenation

Abstract Predictive survival models have been proposed to esti-mate survival rates in patients with refractory cardio-genic shock considered for veno-arterial extracorporeal membrane oxygenation (VA-ECMO) [1, 2]. Notably, the Survival after..

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Why left atrial venting fails to influence extracorporeal life support survival in cardiogenic shock: Unravelling the intricate reality of unloading

Abstract Over the past decade, extracorporeal life support (ECLS) has gained increasing utilization in the management of refractory cardiogenic shock (CS) with a class IIaC recommendation according to the latest..

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Routine venoarterial extracorporeal membrane oxygenation for acute myocardial infarction‑related cardiogenic shock: what we know and don’t know

Abstract Acute myocardial infarction-related cardiogenic shock (AMI-CS) carries a dismal prognosis. Short-term mortality is in the range of 40–50% [1]. Until recently, only treatment of the culprit lesion by percutaneous..

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Beyond one-size-fits-all in cardiogenic shock: impella, extracorporeal membrane oxygenation or tailored use of mechanical circulatory support?

Abstract Purpose of review  This article offers an overview of recent randomized controlled trials (RCTs) testing the efficacy of veno-arterial extracorporeal membrane oxygenation (VA ECMO) and microaxial flow pump (mAFP)..

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Mechanical circulatory support in cardiogenic shock: microaxial flow pumps for all and VA‑ECMO consigned to the museum?

Abstract Introduction Mortality rates in cardiogenic shock remain high, especially in patients with SCAI shock stages C to E [1].When hemodynamic status does not improve or worsens despite optimal fluid,..

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Intra-aortic balloon pump in patients undergoing VA-ECMO: an analysis of the Chinese Extracorporeal Life Support Registry

Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has been increasingly used to treat refractory cardiogenic shock (CS) or cardiac arrest (CA) over the past decades. Peripheral VA-ECMO increases left ventricular (LV)..

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