Archives

thumbnail
0 comment

A Comparison of Prothrombin Complex Concentrate and Recombinant Activated Factor VII for the Management of Bleeding With Cardiac Surgery

Abstract Bleeding following cardiac surgery that warrants transfusion of blood products is associated with significant complications, including increased mortality at 1 year following surgery. Factor concentrates, such as prothrombin complex..

Read More
thumbnail
0 comment

Polypropylene Oxygenators: Risk Of SARS-Cov-2 Contamination in The Operation Theatre?

Abstract It is established that coronaviruses are transmitted most through aerosols produced when an infected individual coughs or sneezes. Although there is no clear evidence of person-to-person airborne transmission, it is..

Read More
thumbnail
0 comment

SARS-CoV-2 Does Not Spread Through Extracorporeal Membrane Oxygenation or Dialysis Membranes

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a major worldwide health threat in just a few weeks. ICU admission and the recourse to extracorporeal organ support, such..

Read More
thumbnail
0 comment

Improving Perioperative Brain Health: An Expert Consensus Review of Key Actions for The Perioperative Care Team

Abstract Delirium and postoperative neurocognitive disorder are the commonest perioperative complications in patients more than 65 yr of age. However, data suggest that we often fail to screen patients for..

Read More
thumbnail
0 comment

Early alterations in heart rate are associated with poor outcome in patients with intracerebral hemorrhage

Abstract Purpose Cardiac complications are common after spontaneous intracerebral hemorrhage (ICH). In this study we intended to investigate factors associated with higher alterations in heart rate and their impact on..

Read More
thumbnail
0 comment

Veno-venous extracorporeal membrane oxygenation allocation in the COVID-19 pandemic

Abstract Rapid global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the resultant clinical illness, coronavirus disease 2019 (COVID-19), drove the World Health Organization to declare COVID-19 a..

Read More
thumbnail
0 comment

Preoperative Endothelial Dysfunction in Cutaneous Microcirculation Is Associated with Postoperative Organ Injury After Cardiac Surgery Using Extracorporeal Circulation: A Prospective…

Abstract Background Cardiac surgery is known to induce acute endothelial dysfunction, which may be central to the pathophysiology of postoperative complications. Preoperative endothelial dysfunction could also be implicated in the..

Read More
thumbnail
0 comment

Risk Assessment of Acute Kidney Injury Following Cardiopulmonary Bypass

Abstract Background Acute kidney injury (AKI) is a frequent and serious complication of cardiac surgery, associated with a high incidence of morbidity and mortality. Although the RIFLE criteria serve as..

Read More
thumbnail
0 comment

Hemolysis at Low Blood Flow Rates: In-Vitro and In-Silico Evaluation of A Centrifugal Blood Pump

Abstract Background Treating severe forms of the acute respiratory distress syndrome and cardiac failure, extracorporeal membrane oxygenation (ECMO) has become an established therapeutic option. Neonatal or pediatric patients receiving ECMO,..

Read More
thumbnail
0 comment

Perioperative Outcomes of Coronary Artery Bypass Graft Surgery in Johannesburg, South Africa

Abstract Background The perioperative complications in patients with coronary artery disease undergoing coronary artery bypass graft (CABG) surgery have been reported predominantly from developed countries, with a paucity of data..

Read More
thumbnail
0 comment

Universal Definition of Perioperative Bleeding in Cardiac Surgery Adults and Association with Mortality in A Mexican Cardiovascular Critical Care Unit

Abstract Background Bleeding as a complication is associated with poorer results in cardiac surgery. There is increasing evidence that the use of blood products is an independent factor of increased..

Read More
thumbnail
0 comment

The Correlation Between Bowel Complications and Cardiac Surgery

Abstract Although advances in knowledge and technology have improved outcomes in surgical cardiac patients over the last decade, complications following cardiac operations still remain to be potentially fatal. Gastrointestinal complications,..

Read More
thumbnail
0 comment

Increased Cerebral Mitochondrial Dysfunction and Reactive Oxygen Species with Cardiopulmonary Bypass

Abstract Objectives Neurodevelopmental injury after cardiac surgery using cardiopulmonary bypass (CPB) for congenital heart defects is common, but the mechanism behind this injury is unclear. This study examines the impact..

Read More
thumbnail
0 comment

Unilateral or Bilateral Cerebral Perfusion in Hemiarch Replacement: A Prospective Randomized Study

Abstract Background We designed a prospective randomized clinical study to compare unilateral and bilateral antegrade cerebral perfusion (ACP) under moderate hypethermia in open distal aortic hemiarch replacement in ascending aortic..

Read More
thumbnail
0 comment

Anemia in Cardiac Surgery – Can Something Bad Get Worse?

Abstract Introduction Anemia and blood transfusion are risk factors for morbidity/mortality in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). The objective of this study is to analyze the association..

Read More
thumbnail
0 comment

Management of Congenital Cardiac Surgery During COVID-19 Pandemic

Abstract The new coronavirus infection, which was first seen in China in late December, 2019 and eventually became a worldwide pandemic, poses a serious threat to public health. After a..

Read More
thumbnail
0 comment

Save It-Don’t Waste It! Maximizing Utilization of Erythrocytes From Previously Stored Whole Blood

Abstract Background  Recent military and civilian experience suggests that fresh whole blood may be the preferred for treatment of hemorrhagic shock, but its use is limited by its 21-day shelf life. The red..

Read More
thumbnail
0 comment

Epidemiology and Clinical Characteristics of Bloodstream Infection in Patients Under Extracorporeal Membranous Oxygenation

Abstract Background Bloodstream infection (BSI) is an important complication of extracorporeal membranous oxygenation (ECMO) and a major cause of mortality. This study evaluated the epidemiological and clinical characteristics of BSI..

Read More
thumbnail
0 comment

Determining Optimal Treatment to Correct Preoperative Anemia and Reduce Perioperative Allogeneic Blood Transfusions in Cardiac Surgery: A Retrospective Cohort Study

Abstract Objective Preoperative anemia management reduces red blood cell (RBC) transfusion and adverse outcomes, but how best to optimize the patient’s hemoglobin (Hgb) before cardiac surgery remains unclear. The authors..

Read More
thumbnail
0 comment

Low Microcirculatory Perfused Vessel Density and High Heterogeneity are Associated with Increased Intensity and Duration of Lactic Acidosis After Cardiac…

Introduction Lactic acidosis after cardiac surgery with cardiopulmonary bypass is common and associated with an increase in postoperative morbidity and mortality. A number of potential causes for an elevated lactate..

Read More
thumbnail
0 comment

Anticoagulation Management and Antithrombin Supplementation Practice during Veno-venous Extracorporeal Membrane Oxygenation: A Worldwide Survey

Background There is a lack of consensus on how to manage anticoagulation during veno-venous extracorporeal membrane oxygenation, including antithrombin monitoring and supplementation. The authors’ aim was to determine current practice..

Read More
thumbnail
0 comment

Veno-arterial-ECMO in the intensive care unit: From technical aspects to clinical practice

The use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) as a salvage therapy in cardiogenic shock is becoming of current practice. While VA-ECMO is potentially a life-saving technique, results are sometimes mitigated, emphasising the need for selecting..

Read More
thumbnail
0 comment

Venoarterial Extracorporeal Membrane Oxygenation in Cardiogenic Shock

Venoarterial extracorporeal membrane oxygenation has emerged as a viable treatment for patients in cardiogenic shock with biventricular failure and pulmonary dysfunction. Advances in pump and oxygenator technology, cannulation strategies, patient selection and management, and durable mechanical circulatory support have..

Read More
thumbnail
0 comment

Cannulation Strategies in Adult Veno-arterial and Veno-venous Extracorporeal Membrane Oxygenation: Techniques, Limitations, and Special Considerations

Abstract Extracorporeal membrane oxygenation (ECMO) refers to specific mechanical devices used to temporarily support the failing heart and/or lung. Technological advances as well as growing collective knowledge and experience have..

Read More
thumbnail
0 comment

Hyperoxia in patients with cardiogenic shock after myocardial infarction supported with venoarterial extracorporeal membrane oxygenation

Background Venoarterial extracorporeal membrane oxygenation (V-A ECMO) improves perfusion and oxygenation in patients with cardiogenic shock. However, it can also result in supranormal oxygen exposure. Recent evidence suggests hyperoxia may..

Read More
thumbnail
0 comment

Advanced mechanical circulatory support for post-cardiotomy cardiogenic shock: a 20-year outcome analysis in a non-transplant unit

Background Post-cardiotomy cardiogenic shock (PCCS) has an incidence of 2–6 % after routine adult cardiac surgery. 0.5–1.5 % are refractory to inotropic and intra-aortic balloon pump (IABP) support. Advanced mechanical circulatory support..

Read More
thumbnail
0 comment

Extra-corporeal membrane oxygenation for refractory cardiogenic shock after adult cardiac surgery: a systematic review and meta-analysis

Background Postcardiotomy cardiogenic shock (PCCS) refractory to inotropic support and intra-aortic balloon pump (IABP) occurs rarely but is almost universally fatal without mechanical circulatory support. In this systematic review and..

Read More
thumbnail
0 comment

Preoperative extracorporeal membrane oxygenation as a bridge to cardiac surgery in children with congenital heart disease

Background The efficacy of extracorporeal membrane oxygenation (ECMO) in bridging children with unrepaired heart defects to a definitive or palliative surgical procedure has been rarely reported. The goal of this..

Read More
thumbnail
0 comment

International survey on the management of mechanical ventilation during ECMO in adults with severe respiratory failure

BACKGROUND: No consensus exists on the optimal settings of mechanical ventilation during veno-venous extracorporeal membrane oxygenation (ECMO). Our aim was to describe how mechanical ventilation and related interventions are managed..

Read More
thumbnail
0 comment

Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019 in Shanghai, China

Severe cases of coronavirus disease 2019 (COVID-19) cannot be adequately managed with mechanical ventilation alone. The role and outcome of extracorporeal membrane oxygenation (ECMO) in the management of COVID-19 is..

Read More