Objective Adequate , measured using (ACT), is important during vascular and cardiac surgeries. Unfractionated heparin is the most common used. The purpose of this analysis was to compare the i-STAT ACT (iACT) to..
Read MoreCURRENTLY, MINIMALLY INVASIVE cardiac surgery (MICS) is very popular. In most cases, cardiopulmonary bypass (CPB) is used with femoral arterial cannulation, and the whole body is perfused in a retrograde..
Read MoreHYPOTHERMIC CIRCULATORY arrest combined with selective cerebral perfusion commonly is employed to permit surgical repair of the ascending and transverse aorta. A variety of perfusion techniques are employed, including retrograde..
Read MoreAbstract Introduction: Pulsatile extracorporeal circulation may improve organ perfusion during cardiac surgery. Some minimally invasive extracorporeal circulation (MiECC) systems allow pulsatile perfusion. The present study investigated the influence of arterial..
Read MoreAbstract In a randomized clinical trial in China of 244 adults undergoing elective, multiple valve replacement surgery, Lei and colleagues administered 80 parts per million nitric oxide (NO) gas during..
Read MoreAbstract Extracorporeal circulation causes many deleterious effects on blood cells. Low-level light therapy (LLLT) in the red/near-infrared spectral range is known for its cytoprotective properties but its use during cardiopulmonary..
Read MoreAbstract BACKGROUND: Tranexamic acid (TXA) is a common antifibrinolytic agent used to minimize bleeding in cardiac surgery. Up to 50% cardiac surgical patients have chronic renal dysfunction (CRD). Optimal dosing..
Read MoreAbstract (IE) after (TAVI) and surgical (SAVR) is a rare but life-threatening complication. Paravalvular regurgitation, compression of native leaflets, and space between transcatheter and native valves could dispose recipients at increased risk of IE..
Read MoreAbstract Background For diabetic patients who require (CABG) operation, controversy persists whether an off-pump or an on-pump approach may be advantageous. This US-based, multicenter, randomized, controlled trial, Department of Veterans Affairs..
Read MoreAbstract Veno-arterial (V-A) extracorporeal membrane oxygenation (ECMO) is increasingly commonly used to treat acute cardiac or pulmonary failure because of a wide range of etiologies. However, despite progressively improving outcomes,..
Read MoreAbstract The use of extracorporeal circulation for cardiac surgery and extracorporeal life support poses tremendous challenges to the hemostatic equilibrium given its diametric tendency to trigger hyper‐ and hypocoagulopathy. The..
Read MoreAbstract Objectives The aim of this pilot study was to elucidate the effects of exogenous (NO) supply to the circuit for cardioprotection against during (CABG) with (CPB). Methods A total of 60 patients with scheduled for..
Read MoreAbstract Introduction: Patients under the error-prone and complication-burdened extracorporeal membrane oxygenation (ECMO) are looked after by a highly trained, multidisciplinary team. Simulation-based training (SBT) affords ECMO centers the opportunity to..
Read MoreAbstract There is a delicate balance between bleeding and clotting in patients on circuits such as ventricular assist devices or extracorporeal membrane oxygenation. Traditional coagulation tests, prothrombin time, activated partial..
Read MoreAbstract The use of minimized cardiopulmonary bypass support to reduce the side effects of extracorporeal circulation is still contradictorily discussed. This study compares perfusion operated by conventional (CCPB) and minimized..
Read MoreAbstract Measurement of lactate concentrations during cardiac surgery with cardiopulmonary bypass (CPB) is a reliable monitoring tool for the assessment of the adequacy of perfusion, and a predictor of poor..
Read MoreAbstract OBJECTIVES To assess the incidence and outcome of heparin-induced thrombocytopaenia (HIT) in patients after cardiac surgery on cardiopulmonary bypass (CPB) and to review the time course of platelet counts..
Read MoreAbstract Purpose To examine the effect of discontinuing hydroxyethyl starch (HES) solutions on length of hospital stay, transfusion, risk of death, acute kidney injury (AKI), and dialysis. Methods We conducted..
Read MoreAbstract Acute aortic syndromes are a distinct group of pathologies involving the wall of the aorta that present acutely and can be potentially fatal unless treated in a timely fashion...
Read MoreAbstract Complications and critical events during cardiopulmonary bypass (CPB) are very challenging, difficult to manage, and in some instances have the potential to lead to fatal outcomes. Massive cerebral air..
Read MoreAbstract Background: Ultrafiltration during cardiopulmonary bypass (CPB) reduces fluid overload and inflammatory mediators in open-heart surgery and is thought to reduce the risk of red blood cell (RBC) transfusion. We..
Read MoreAbstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has been used for refractory cardiogenic shock; however, it is associated with increased left ventricular afterload. Outcomes associated with the combination of a percutaneous..
Read MoreAbstract In this issue of the ASAIO Journal, Keane et al. present the results of their exploratory study on the combined use of whole body bioimpedance (WBB) and relative blood volume (RBV)..
Read MoreAbstract Background: Patients requiring V-A ECMO who receive femoral cannulation have an associated risk of distal, lower-limb hypoperfusion and ischemia of the cannulated leg. This pilot study evaluated the usefulness..
Read MoreAbstract Temporary mechanical circulatory support (TCS) is recommended for patients with profound cardiogenic shock (CS). Extracorporeal membrane oxygenation (ECMO) and Impella are possible TCS devices, but the device choice and the implantation..
Read MoreAbstract Essentials Heparin‐protamine balance (HPB) modulates bleeding after neonatal cardiopulmonary bypass (CPB). HPB was examined in 44 neonates undergoing CPB. Post‐operative bleeding occurred in 36% and heparin rebound in..
Read MoreAbstract OctaplasLG is indicated for use in patients undergoing cardiac surgery who require replacement of multiple clotting factors. The use of OctaplasLG over single-donor fresh frozen plasma (FFP) may have..
Read MoreAbstract Background: Early fluid expansion could prevent postoperative organ hypoperfusion. However, excessive fluid resuscitation adversely influences multiple organ systems. This retrospective, observational study aimed to investigate the relationship between early..
Read MoreAbstract Blood priming is needed for cardiopulmonary bypass (CPB) in neonates and infants to avoid exceeding hemodilution; however, transfusion‐related inflammation affects post‐CPB outcomes in infant open‐heart surgery. Procalcitonin, a newly..
Read MoreAbstract Children who undergo cardiac surgery with cardiopulmonary bypass are a unique population at high risk for postoperative acute kidney injury (AKI) and fluid overload. Fluid management is important in..
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