Kanülierung

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Ultrafiltration During Cardiopulmonary Bypass: Enhanced Review of Clinical Evidence and…

1. Introduction Cardiopulmonary bypass (CPB) leads to pronounced hemodilution and provokes a systemic inflammatory response from blood interaction with artificial surfaces (Ziyaeifard et al., 2014) (, ). Ultrafiltration (UF) mitigates these effects..

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Cardiac Surgery in Hemophilia Patients: Challenges, Management, and Outcomes —…

Introduction Hemophilia is a hereditary bleeding disorder caused by deficiency of clotting factor VIII (Hemophilia A) or factor IX (Hemophilia B), resulting in impaired blood coagulation and a heightened risk..

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Sickle Cell Disease and Cardiopulmonary Bypass: A Multidisciplinary Approach to…

1. Introduction Sickle Cell Disease (SCD) is a chronic, inherited blood disorder resulting from a single point mutation in the β-globin gene. This mutation leads to the production of hemoglobin..

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Minimizing Cardiopulmonary Bypass Time: Are We Saving Lives or Just…

In modern cardiac surgery, cardiopulmonary bypass (CPB) plays a life-saving role. It allows the heart to be stopped safely while the body is perfused with oxygenated blood. However, it’s a..

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Retrograde Cerebral Perfusion in Aortic Arch Surgery: Principles, Practice, and…

1. Introduction Cerebral protection is a cornerstone of successful aortic arch surgery, where the brain is highly vulnerable during periods of circulatory arrest. While deep hypothermic circulatory arrest (DHCA) alone..

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Antegrade Cerebral Perfusion in Aortic Surgery: Techniques, Evidence, and Future…

1. Introduction Aortic arch surgery presents significant neurologic risks due to the potential for cerebral ischemia during circulatory arrest. Traditional methods such as deep hypothermic circulatory arrest (DHCA) provided limited..

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The Hidden Engineering Behind Cannula Design: How Tip Geometry and…

Introduction: More Than Just a Tube In the world of cardiopulmonary bypass (CPB), the arterial cannula is far more than a simple conduit for blood flow. Every feature—from the shape..

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The Role of Cannula Design in Optimizing CPB Flow Dynamics

In the complex world of cardiopulmonary bypass (CPB), where precision, safety, and efficiency govern every aspect of patient care, the significance of flow dynamics cannot be overstated. While the primary..

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How to Maintain Splanchnic Perfusion: A Practical Clinical Guide

Introduction Splanchnic perfusion refers to the blood flow through the splanchnic circulation, which supplies the gastrointestinal organs including the stomach, intestines, liver, pancreas, and spleen. Maintaining adequate splanchnic blood flow..

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Flow Matters: Revisiting Pulsatility in Cardiopulmonary Bypass.

Introduction The heart is nature’s pulsatile pump, delivering rhythmic surges of blood critical not only for oxygen transport but also for maintaining vascular health. Cardiopulmonary bypass, a lifesaving intervention, often..

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