Abstract Introduction In modern surgical era, local haemostatic agents and blood components such as recombinant activated factor VII (rFVIIa) have expanded surgeons’ armamentarium in controlling “surgical” and “nonsurgical bleeding”. We..
Lire la suiteSummary Observational studies have highlighted the detrimental health effects of shift work. The mechanisms through which acute sleep deprivation may lead to chronic disease have not been elucidated, but it..
Lire la suiteAbstract Congenital heart disease (CHD) often requires surgical intervention, and is sometimes associated with life-threatening post-operative complications. We have investigated some factors of the innate immune system involved in the..
Lire la suiteAbstract Acute mesenteric ischemia (AMI), one of the gastrointestinal system complications, which occurs following cardiac surgery, is challenged in the literature with a diminished incidence of AMI by heart surgery..
Lire la suiteEffect of high- versus low-volume saline administration on acute kidney injury after cardiac surgery
Abstract Background: Fluid resuscitation is critical to perioperative maintenance of adequate preload and cardiac output after cardiac surgery. Liberal use of saline, however, is reportedly associated with an increased risk of..
Lire la suiteAbstract Objectives Rotational (ROTEM)-guided transfusion algorithms in cardiac surgery have been proven to be successful in reducing blood loss in randomized controlled trials. Using an institutional registry of patients in cardiac surgery..
Lire la suiteAbstract Introduction Surgical safety checklists may contribute to reduction of complications and mortality. The WHO’s Surgical Safety Checklist (WHO SSC) could prevent incidents in operating theatres, but errors also occur before..
Lire la suiteAbstract Objectives To describe the incidence and outcomes of radiologically confirmed acute CNS complications in extracorporeal membrane oxygenation patients at an Australian extracorporeal membrane oxygenation referral center and identify associated..
Lire la suiteAbstract Since 2013, rotational thromboelastometry has been available in our hospital to assess coagulopathy. The aim of the study was to retrospectively evaluate the effect of thromboelastometry testing in cardiac..
Lire la suiteAbstract Recent advances in ECLS technology have led to the adoption of centrifugal pumps for the majority of patients worldwide. Despite several advantages of centrifugal pumps, they remain controversial because..
Lire la suiteTrends From 2002 to 2017 Extracorporeal life support (ECLS) has grown in its application since its first clinical description in the 1970s. The technology has been used to support a..
Lire la suiteAbstract It is observed that death rates in cardiac surgery has decreased, however, root causes that behave like triggers of potentially avoidable deaths (AD), especially in low-risk patients (less bias)..
Lire la suiteAbstract In patients with von Willebrand disease (vWD) the interest in age-related comorbidities has grown, because the life expectancy of these patients has increased. The research question of this study..
Lire la suiteAbstract The aim of the study was to describe the Mycobacterium chimaera contamination in heater–cooler devices after the application of a protocol of cleaning and disinfection in a tertiary hospital. It was..
Lire la suiteAbstract Background We describe implementation, evaluate performance, and report outcomes from the first program serving an entire metropolitan area designed to rapidly deliver extracorporeal membrane oxygenation (ECMO)-facilitated resuscitation to patients..
Lire la suiteAbstract We retrospectively reviewed the medical records of 11 patients supported with a veno-venous low-flow extracorporeal carbon dioxide (CO2) removal (ECCO2R) device featuring a large gas exchange surface membrane lung..
Lire la suiteAbstract Background Acute normovolemic hemodilution is recommended as a technique to reduce allogeneic red blood cell (RBC) transfusions in cardiac surgery, but its efficacy to reduce non‐RBC transfusion has not..
Lire la suiteAbstract OBJECTIVES The first aim was the development of a human blood miniature mock-loop system consisting of 2 identical extracorporeal circuits, which enable systematic head-to-head comparisons of test substances. In..
Lire la suiteAbstract Veno-arterial extracorporeal membrane oxygenation (VA ECMO) is widely used in cardiogenic shock. It provides systemic perfusion, but left ventricular (LV) unloading is suboptimal. Using a closed-loop, real-time computer model..
Lire la suiteAbstract Background Right ventricular (RV) dysfunction is a known risk factor for increased mortality in cardiac surgery. However, the association between RV performance and ICU morbidity is largely unknown. Methods..
Lire la suiteAbstract This article outlines recent developments in safety science. It describes the progression of three ‘ages’ of safety, namely the ‘age of technology’, the ‘age of human factors’ and the..
Lire la suiteAbstract Early cancer diagnosis, new therapies that increased survival of patients, besides the increasingly elderly population are some factors would be associated with possible cancer dissemination in patients under cardiopulmonary..
Lire la suiteAbstract AIM To investigate the incidence and risk factors for vancomycin concentrations less than 10 mg/L during cardiac surgery. METHODS In this prospective study, patients undergoing cardiac surgery received a..
Lire la suiteAbstract OBJECTIVES The invention of new surgical procedures requires testing at different stages including animal models. To facilitate this process, we have developed a computer-controlled extracorporeal circulation system for testing..
Lire la suiteAbstract OBJECTIVES Post-cardiotomy cardiogenic shock (PCCS) results in substantial morbidity and mortality, whereas refractory cases require mechanical circulatory support (MCS). The aim of the study was to compare extracorporeal membrane..
Lire la suiteAbstract OBJECTIVES Although total blood volume (TBV) is central to the estimation of the haemodilution rate during cardiopulmonary bypass (CPB), conventional formulas lack sufficient accuracy. The aim of this study..
Lire la suiteAbstract Background The objective of this study was to assess the incidence of in‐hospital acute kidney injury (AKI) after cardiac surgery by comparing preoperative baseline renal function with renal function..
Lire la suiteAbstract New threats to effective scientific communication make it more difficult to separate science from science fiction. Patients can be harmed by misinformation or by misplaced trust; for example, patients..
Lire la suiteAbstract The proportion of patients receiving intravenous gelatin‐based colloids has increased in the last decade due to safety concerns about starch‐based products. Recent research suggests hypersensitivity reactions to intravenous gelatin‐based..
Lire la suiteAbstract Aims To assess the associations between bullying and violence at work and cardiovascular disease (CVD). Methods and results Participants were 79 201 working men and women, aged 18–65 years and free..
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