Abstract Background: A standard blood prime for cardiopulmonary bypass (CPB) in congenital cardiac surgery may possess non-physiologic values for electrolytes, glucose, and lactate. Pre-bypass Ultrafiltration (PBUF) can make these values..
Lire la suiteAbstract Disclaimer: These guidelines for routine neuromonitoring in neonatal and pediatric patients supported on extracorporeal membrane oxygenation (ECMO) are intended for educational use to build the knowledge of physicians and other health..
Lire la suiteAbstract Purpose With newer generation diagonal and centrifugal blood pumps gaining popularity, the objective of this study was to compare the DP3-i-cor diagonal and RotaFlow centrifugal pumps in terms of..
Lire la suiteAbstract Background Del Nido cardioplegia (DNc) was designed for superior myocardial protection during cardiopulmonary bypass (CPB). We conducted a retrospective review to explore if DNc was associated with increase in..
Lire la suiteAbstract Perfusion education programs use simulation to provide students with clinical skills prior to entering the operating room. To teach the psychomotor execution of skills in a simulation lab requires..
Lire la suiteAbstract OBJECTIVES: To determine potential risk factors for severe hemolysis during pediatric cardiopulmonary bypass and examine whether supraphysiologic levels of oxygen and cardiopulmonary bypass duration are associated with hemolysis. DESIGN: ..
Lire la suiteAbstract Objectives: To present the recommendations and consensus statements with supporting literature for plasma and platelet transfusions in critically ill neonates and children undergoing cardiac surgery with cardiopulmonary bypass or..
Lire la suiteAbstract Anticoagulation is necessary for most pediatric and adult extracorporeal membrane oxygenation (ECMO) patients to prevent circuit clotting. Inherently, the most common side effect of anticoagulation is bleeding. Anticoagulation during..
Lire la suiteAbstract Extracorporeal life support (ECLS) may be life saving for patients with status asthmaticus (SA), a difficult-to-treat, severe subset of asthma. Contemporary ECLS outcomes for SA in teens and young..
Lire la suiteThis case reports on a 6-month-old female patient (8 kg, 55 cm), who was admitted to the hospital due to severe hyperbilirubinemia. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/01/CoW_03_2022_E_web_compressed.pdf"]
Lire la suiteAbstract Introduction Unfractionated heparin is widely used as an anticoagulant for extracorporeal life support (ECLS) and usually monitored with activated partial thromboplastin time (aPTT). Due to its limitations in pediatric..
Lire la suiteAbstract Objectives: To describe the use of extracorporeal membrane oxygenation (ECMO) in the management of pediatric poisoning in the United States and to identify predictors of mortality. Design: Retrospective cohort study. Setting: ..
Lire la suiteAbstract This retrospective cohort study describes all children transported on extracorporeal life support (ECLS) by the Stollery Children’s Hospital Pediatric Transport team (SCH-PTT) between 2004 and 2018. We compared outcomes..
Lire la suiteAbstract OBJECTIVES: Patients in the pediatric cardiac ICU are frequently exposed to pharmacologic and environmental factors that predispose them to sleep disturbances and may increase the risk of delirium. In..
Lire la suiteAbstract Children show important developmental and maturational changes, which may contribute greatly to pharmacokinetic (PK) variability observed in pediatric patients. These PK alterations are further enhanced by disease-related, non-maturational factors...
Lire la suiteAbstract Background Pediatric heart transplant (HTx) recipients with congenital heart defects require complex concomitant surgical procedures with the risk of prolonging the allograft’s ischemic time. Ex vivo allograft perfusion with the..
Lire la suiteAbstract Background: Extracorporeal membrane oxygenation (ECMO) is increasingly utilized for pediatric sepsis unresponsive to steroids and inotropic support. Outcomes of children with sepsis are influenced by the type of pathogen causing..
Lire la suiteAbstract An 11-year-old female patient was admitted to a pediatric intensive care unit for the treatment of acute respiratory distress syndrome (ARDS). She had received peripheral blood stem cell transplantation..
Lire la suiteAbstract Objectives The monitoring of cerebral tissue oxygen saturation by near-infrared spectroscopy (ScerebO2) is used widely in pediatric cardiac anesthesia. However, little information is available on the effects of changes..
Lire la suiteThe case reports on a 17-year-old boy (weight 70 kg) transferred to the Children Infections Research Center intensive care unit (ICU) with severe jaundice and in a poor general condition..
Lire la suiteAbstract Introduction: To our knowledge, methylprednisolone pharmacokinetics and plasma concentrations have not been comprehensively investigated in children with congenital heart disease undergoing cardiac surgery with cardiopulmonary bypass. It is unknown whether..
Lire la suiteAbstract Background Blood pressure variability (BPV), defined as the degree of variation between discrete blood pressure readings, is associated with poor outcomes in acute care settings. Acute kidney injury (AKI)..
Lire la suiteThis case reports on a 16-year-old male patient (weight 56 kg), who was admitted from the hematology-oncology ward to the Pediatric Intensive Care Unit (PICU) after a clinical deterioration with..
Lire la suiteAbstract Extracorporeal membrane oxygenation (ECMO) is an invaluable means of supporting critically ill children with refractory respiratory or cardiac failure. Controversy remains; however, whether roller or centrifugal pumps are superior,..
Lire la suiteAbstract Substantial progress has been made in the standardization of nomenclature for paediatric and congenital cardiac care. In 1936, Maude Abbott published her Atlas of Congenital Cardiac Disease, which was..
Lire la suiteAbstract Purpose: Complications associated with use of dual-lumen venovenous extracorporeal membrane oxygenation (VV-ECMO) cannulas are of concern in pediatric patients. While the risk of atrial perforation is believed to be..
Lire la suiteAbstract The use of cardiopulmonary bypass (CPB) can be associated with significant hemodilution, coagulopathy and a systemic inflammatory response for infants and children undergoing cardiac surgery. Intra-operative ultrafiltration has been..
Lire la suiteThis case reports on a 14-year-old previously healthy girl who was referred to the Pediatric Intensive Care Unit (PICU) with a suspicion of multisystem inflammatory syndrome in children (MIS-C) and..
Lire la suiteAbstract OBJECTIVES: During the early postoperative period, children with congenital heart disease can suffer from inadequate cerebral perfusion, with possible long-term neurocognitive consequences. Cerebral tissue oxygen saturation can be monitored..
Lire la suiteAbstract Background Amongst children with congenital heart disease (CHD), earlier age of repair improves cardiovascular outcomes. The effects of early intervention on neurodevelopment remains unclear. We assessed the association between..
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