Archives annuelles: 2025

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Hyperoxia and End-Organ Complications Among Cardiogenic Shock Patients Supported by Veno-Arterial Extracorporeal Membrane Oxygenation

Abstract Abstract Objectives:  To investigate whether severe hyperoxia predisposes to end-organ complications and whether these complications contribute to in-hospital mortality among cardiogenic shock (CS) patients supported in veno-arterial extracorporeal membrane..

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Cardiogenic shock: diagnosis, phenotyping and management

Abstract Cardiogenic shock (CS) is a state of critical end-organ hypoperfusion caused by primary cardiac failure, in which the heart cannot generate sufficient output despite adequate preload and is associated..

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Women’s cardiovascular health at risk: an urgent call to protect the US biomedical research system and prevent setbacks in women’s…

Abstract Rigorous research in cardiovascular physiology and medicine has led to critical advancements in preventing, diagnosing, and treating cardiovascular disease; however, striking disparities persist in cardiovascular disease prevention, diagnosis, and..

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Assessing the Efficacy of Pathogen-Reduced Platelet Transfusions for Hemostasis in Children Undergoing Cardiopulmonary Bypass Surgery

Abstract Background Children undergoing cardiopulmonary bypass (CPB) surgery are vulnerable to bleeding and often require transfusions. Pathogen-reduced (PR) platelets may reduce microbial contamination but are associated with decreased platelet count..

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Extracorporeal membrane oxygenation cannula dressing and securement practices: A point prevalence study

Abstract Background Effective securement of extracorporeal membrane oxygenation (ECMO) cannulae, both at the insertion site and along the length of circuit tubing, may reduce the risk of cannula migration, dislodgement,..

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Investigating the Impact of Cannula Size on Pump Operation and Hemodynamics in an In Silico Clinical Trial

Abstract Veno-arterial extracorporeal membrane oxygenation (V‑A ECMO) is a critical care therapy for patients with severe cardiorespiratory failure, and it is associated with high in‑hospital mortality rates. Causes are the..

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Use of Temporary Ventricular Assist Devices for Left Ventricular Unloading During Venoarterial Extracorporeal Membrane Oxygenation Support

Venoarterial extracorporeal membrane oxygenation (VA ECMO) provides temporary mechanical circulatory support for patients in refractory cardiogenic shock. Initiation of VA ECMO often results in increased left ventricular (LV) afterload as..

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Rescue Team Course Paris - 1/3 Dec

Special 3 day Rescue Team Course Paris NEXT SESSION 1 to 3 December for 2025 . Come learn all you need to know on OHCA, ECPR and REBOA during a..

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Ultrafiltration During Cardiopulmonary Bypass: Enhanced Review of Clinical Evidence and Application

1. Introduction Cardiopulmonary bypass (CPB) leads to pronounced hemodilution and provokes a systemic inflammatory response from blood interaction with artificial surfaces (Ziyaeifard et al., 2014) (, ). Ultrafiltration (UF) mitigates these effects..

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Cardiac Surgery in Hemophilia Patients: Challenges, Management, and Outcomes — A Review of Evidence

Introduction Hemophilia is a hereditary bleeding disorder caused by deficiency of clotting factor VIII (Hemophilia A) or factor IX (Hemophilia B), resulting in impaired blood coagulation and a heightened risk..

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Blood Transfusions are Associated With Prolonged Mechanical Ventilation Following Cardiac Surgery in Neonates

Abstract Background: To investigate the factors that influence blood transfusions after neonatal cardiac surgery and their association with prolonged mechanical ventilation (PMV) to provide a basis for optimizing blood transfusion..

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The progress and trends of the mechanism of cardiopulmonary bypass-associated acute lung injury: A narrative review

Abstract Studies into the mechanisms of cardiopulmonary bypass-associated acute lung injury have not presented breakthroughs for many years, resulting in the stagnation of management strategies and clinical medicine measures. This..

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The organ-protective effects of nitric oxide in adult patients undergoing cardiac surgery with cardiopulmonary bypass: a systematic review and meta-analysis

Abstract Postoperative organ dysfunction remains a major challenge in adult cardiac surgery with cardiopulmonary bypass (CPB), frequently involving the kidneys, heart, and lungs. These complications are primarily driven by hemolysis,..

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Clinical Outcomes of Cardiogenic Shock Patients Supported with VA-ECMO: Insights from the Cardiogenic Shock Working Group

Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) use for cardiogenic shock (CS) is increasing worldwide despite conflicting results from randomized trials, which focused on myocardial-infarction related CS (MI-CS). Methods We..

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Is Cardiac Surgery Safe During GenAI exceeds clinical experts in predicting acute kidney injury following paediatric cardiopulmonary bypassPregnancy?

Abstract The emergence of large language models (LLMs) opens new horizons to leverage, often unused, information in clinical text. Our study aims to capitalise on this new potential. Specifically, we..

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Network meta-analysis of cardioplegic methods, in elective isolated coronary artery bypass grafting

Abstract Background Cardioplegic arrest can be induced by various methods, fueling a long-standing controversy about their comparative merit. We aim to compare cardioplegic methods in coronary artery disease. Methods PubMed,..

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Aortic Balloon Occlusion in Circulatory Determination of Death Donors Undergoing Abdominal Normothermic Regional Perfusion?

Abstract Normothermic regional perfusion (NRP) is a strategy of postmortem reperfusion with warm oxygenated blood of a portion of the body applied in donors undergoing circulatory determination of death (DCDDs)...

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Perioperative use and accuracy of continuous glucose monitoring: A systematic review

Abstract Perioperative impairment of glycaemic control significantly increases the risk of major postoperative complications. The use of continuous glucose monitoring (CGM) has demonstrated benefits in glycaemic control, but its use..

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Brain First: Carotid Artery Access for Cerebral and Arterial Perfusion in Complex Aortic Surgery

Abstract The common carotid artery (CCA) is an easily accessible means of providing cerebral and systemic perfusion during complex aortic surgery. Our technique for using CCA perfusion through a graft..

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Extracorporeal and Conventional Cardiopulmonary Resuscitation and Low‐Flow Duration: Insights From a Nationwide Hospital‐Based Registry Study in Japan (JAAM‐OHCA Registry)

Abstract Background The optimal low‐flow duration (LFD) for extracorporeal cardiopulmonary resuscitation (ECPR) and conventional cardiopulmonary resuscitation (CCPR) remains unclear. We evaluated the impact of LFD on neurological outcomes based on..

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Mixed Venous Oxygen Saturation Has a Poor Association with Cardiac Index during Early Intensive Care Unit Stay after Cardiac Surgery

Abstract Objectives Our aim was to assess the association between mixed venous oxygen saturation (SvO2) and cardiac index (CI) among cardiac surgical patients during the initial 4 hours in the..

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Exploration of mortality-associated creatinine thresholds for acute kidney injury in cardiac surgery patients with impaired kidney function: a single-center retrospective…

Abstract Background Acute kidney injury (AKI) is a frequent and severe complication following cardiac surgery, particularly in patients with impaired kidney function. The existing Kidney Disease: Improving Global Outcomes (KDIGO)..

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Outcomes Following Perioperative Stroke in Cardiac Surgery Patients: A Retrospective Cohort Study

Abstract Objectives To identify independent predictors of 30-day mortality, adverse discharge, and length of hospital stay following a perioperative stroke among cardiac surgical patients, and to measure trends in outcomes..

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Centrifugation versus filtration-based cell salvage: impact on perioperative bleeding in cardiac surgery—the COLTRANE randomised clinical trial – study protocol

Abstract Introduction Cardiac surgery remains a high-risk procedure for bleeding despite advances in patient blood management. Conventional centrifugation-based autotransfusion devices primarily recover red blood cells, losing platelets and coagulation factors. The..

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Early detection of mesenteric ischemia in critically ill patients following cardiac surgery

Abstract Mesenteric ischemia (Me-Is) is a severe complication with high mortality after cardiac surgery. We examined whether intestinal fatty acid binding protein (I-FABP) might serve as a biomarker for early..

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Risk factors for bleeding and thrombotic complications during extracorporeal membrane oxygenation support in adults based on the MIMIC-IV database

Abstract Objective:   To identify risk factors for bleeding and thrombotic complications during extracorporeal membrane oxygenation (ECMO) support in adults and to develop a predictive model based on these factors...

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Perspectives on the Predictive Role of PvCO2 × Ve/Q for Hyperlactatemia During Cardiopulmonary Bypass

Abstract We read with great interest the article by Kowara et al.,[] which highlights the potential of PvCO2 × Ve/Q as a key predictive marker for hyperlactatemia during cardiopulmonary bypass (CPB). This..

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