Abstract Background: This study examines the results of autopsy examinations specifically aimed at documenting complications arising from the implantation phase and treatment with veno–arterial extracorporeal membrane oxygenation (VA-ECMO) in patients with..
Lire la suiteAbstract Introduction The interaction between primary left ventricular output and Veno-arterial extracorporeal membrane pulmonary oxygenation (VA ECMO) flow may impede the perfusion of aortic vessels with hyperoxic blood, leading to..
Lire la suiteAbstract Background and Objectives: The majority of cardiac surgical procedures are performed using cardiopulmonary bypass and cardioplegia-induced cardiac arrest. Cardiac arrest and reperfusion may lead to ischemia-reperfusion injury of the..
Lire la suiteAbstract Objective To explore whether ultrafiltration (UF) volume adjusted for weight is associated with an increased risk of acute kidney injury (AKI) after cardiopulmonary bypass (CPB) in cardiac surgery patients...
Lire la suiteAbstract Background: Individuals undergoing cardiac surgery face an increased risk of bleeding, as well as alterations in biochemical and coagulation patterns. Therefore, assessing the effectiveness of systems such as Cell..
Lire la suiteAbstract Background Studies estimating risks after cardiac surgery for patients receiving kidney replacement therapy have been limited by the size and generalizability of those cohorts. This study used data linked..
Lire la suiteAbstract As the medical complexity of pregnant patients increases, the rate of maternal morbidity has risen. Maternal cardiovascular disease is a leading cause of maternal morbidity and mortality followed closely..
Lire la suiteAbstract Patient blood management (PBM) encompasses implementing multimodal evidence-based strategies to screen, diagnose, and properly treat anaemia and coagulopathies using goal-directed therapy while minimising bleeding. The aim of PBM is..
Lire la suiteAbstract Background The use of Extracorporeal Membrane Oxygenation (ECMO) remains associated with high rates of complications, weaning failure and mortality which can be partly explained by a knowledge gap on..
Lire la suiteAbstract Purpose Blood is commonly treated as single-phase homogeneous fluid in numerical simulations of blood flow within fiber bundles of blood oxygenators. However, microfluidics tests revealed the presence of hematocrit..
Lire la suiteAbstract Objectives To assess whether angiotensin II infusion increases pulmonary vascular resistance (PVR) relative to norepinephrine. Design Secondary analysis of a double-blinded randomized feasibility study. Setting Two tertiary metropolitan hospitals..
Lire la suiteAbstract Extracorporeal membrane oxygenation (ECMO) is a type of mechanical circulatory support that is increasingly utilized in the United States for severe respiratory and/or cardiac failure refractory to conventional therapies...
Lire la suiteAbstract Introduction Cardiotomy suction blood is used in cardiopulmonary bypass (CPB) surgery to maintain blood volume in the CPB system, although it is known to contain micro emboli, cytokines and..
Lire la suiteAbstract Extracorporeal Carbon Dioxide Removal (ECCO2R) systems support patients with severe respiratory failure. Concurrent ambulation and physical therapy improve patient outcomes, but these procedures are limited by the complexity and..
Lire la suiteAbstract Introduction Since the early 2000's, the appeal of certain operating room specialties has decreasedamong medical school graduate students. The recent reform of the second and third cycles of medical..
Lire la suiteAbstract Objective To evaluate the impact of intraoperative neuromonitoring (IONM) on stroke and operative mortality after coronary and/or valvular operations. Methods This was an observational study of coronary and/or valvular heart operations..
Lire la suiteAbstract Introduction Bleeding after cardiac surgeries holds risk of mortality and morbidity in pediatrics. This systematic review aimed to evaluate postoperative blood loss and blood transfusion requirements for pediatric patients..
Lire la suiteAbstract Background and objectives: California is one of a few states with mandatory reporting of mortality after coronary artery bypass graft (CABG) surgery. The Affordable Care Act restructured Medicaid, preferentially..
Lire la suiteAbstract Fetal cardiac intervention consists of a novel and evolving technique for the intrauterine treatment of a subset of patients with congenital heart diseases, which aims to improve hemodynamics, reduce..
Lire la suiteAbstract Direct oral anticoagulants (DOACs) are increasingly being used due to their improved efficacy/safety ratio and lower clinical and economic burden when compared to vitamin K antagonists. However, bleeding is..
Lire la suiteAbstract Background Understanding of the hemostatic and complement alterations associated with cardiopulmonary bypass (CPB) in pediatric patients and the impact of these alterations on outcome is limited. Objectives The present..
Lire la suiteAbstract Background: Pro- and anti-inflammatory cytokines help regulate the inflammatory response. A cytokine storm is a dysregulated cytokine response associated with sepsis and other conditions that result in a hyper-inflammatory state...
Lire la suiteAbstract Blood management is a critical aspect of patient care during surgical procedures. In the United Kingdom, there is a growing recognition of the need to integrate intraoperative cell salvage..
Lire la suiteAbstract Chen et al. used a rat model of cardiopulmonary bypass followed by 30-min ischemia (induced by ascending aorta blockage) and 15-min reperfusion []. They reported that pyruvate dehydrogenase E1α..
Lire la suiteAbstract OBJECTIVES Brain-protective strategies for acute type A aortic dissection (TAAD) remain controversial. Moderate hypothermia circulatory arrest (MHCA) without cerebral perfusion is not commonly used. However, we aimed to assess..
Lire la suiteAbstract OBJECTIVES Long cardiopulmonary bypass times are associated with adverse postoperative outcomes and increased healthcare resource use. It is likely that this effect is pronounced in smaller patients. Previous studies..
Lire la suiteAbstract Introduction The mobilization and ambulation of patients with severe cardiogenic shock supported with peripheral veno-arterial extracorporeal membrane oxygenation (pVA-ECMO) and concomitant femoral intra-aortic balloon pump (IABP) support is not..
Lire la suiteAbstract Whereas studying the aortic valve in isolation has facilitated the development of life-saving procedures and technologies, the dynamic interplay of the aortic valve and its surrounding structures is vital..
Lire la suiteAbstract Neurological complications related to cardiac surgery present physicians with challenges. These complications severely impact patients’ outcomes, the quality of their lives, and affect the resources available at healthcare centers...
Lire la suiteAbstract Introduction A well-known complication of veno-arterial extracorporeal membrane oxygenation (VA ECMO) is differential hypoxia, in which poorly-oxygenated blood ejected from the left ventricle mixes with and displaces well-oxygenated blood..
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