Perfusfind S.L.
thumbnail
0 comment

‘He’s done so well’: Recipient of first new generation heart transplant is recovering as expected

A Duke medical team successfully performed the first new generation artificial heart transplant in history in July. Over a month later, recipient Matthew Moore is recovering as expected.   The recipient’s wife..

Read More
thumbnail
0 comment

Clinician Ethical Perspectives on Extracorporeal Membrane Oxygenation in Practice

Abstract Purpose: Extracorporeal membrane oxygenation (ECMO) is an expensive and scarce life sustaining treatment provided to certain critically ill patients. Little is known about the informed consent process for ECMO..

Read More
thumbnail
0 comment

The Albumin-to-Fibrinogen Ratio Independently Predicts Acute Kidney Injury in Infants With Ventricular Septal Defect Undergoing Cardiac Surgery With Cardiopulmonary Bypass

Abstract Background: Acute kidney injury (AKI) is a common and serious complication faced by children following ventricular septal defect (VSD) surgery with cardiopulmonary bypass (CPB). The objective of this study was..

Read More
thumbnail
0 comment

The Association of Matrix Metalloproteinases With Acute Kidney Injury Following CPB-Supported Cardiac Surgery

Abstract Background: Cardiac surgery–associated acute kidney injury (AKI) is an adverse outcome that increases morbidity and mortality in patients undergoing cardiac surgical procedures. To date, the use of serum creatinine..

Read More
thumbnail
0 comment

Severe thrombocytopenia in adults undergoing extracorporeal membrane oxygenation is predictive of thrombosis

Abstract Extracorporeal membrane oxygenation (ECMO) provides lifesaving circulatory support and gas exchange, although hematologic complications are frequent. The relationship between ECMO and severe thrombocytopenia (platelet count <50 × 109/L) remains ill-defined. We performed..

Read More
thumbnail
0 comment

Cross-Circulation for Extracorporeal Liver Support in a Swine Model

Abstract Although machine perfusion has gained momentum as an organ preservation technique in liver transplantation, persistent organ shortages and high waitlist mortality highlight unmet needs for improved organ salvage strategies...

Read More
thumbnail
0 comment

Increased mortality in patients with COVID-19 receiving extracorporeal respiratory support during the second wave of the pandemic

Abstract Dear Editor, In the earliest phases of the pandemic, the use of extracorporeal life support in patients with severe coronavirus disease 2019 (COVID-19) was associated with disastrous outcomes. However,..

Read More
thumbnail
0 comment

Dynamic and Hybrid Configurations for Extracorporeal Membrane Oxygenation

Abstract Dynamic or hybrid configurations for extracorporeal membrane oxygenation (ECMO) are needed when patient physiology or clinical conditions change. Dynamic configurations included configurations converting from veno-arterial (V-A) ECMO or veno-venous..

Read More
thumbnail
0 comment

Centrifugal and Roller Pumps in Neonatal and Pediatric Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is an invaluable means of supporting critically ill children with refractory respiratory or cardiac failure. Controversy remains; however, whether roller or centrifugal pumps are superior,..

Read More
thumbnail
0 comment

The Potential Role of Extracorporeal Cytokine Removal in Hemodynamic Stabilization in Hyperinflammatory Shock

Abstract Hemodynamic instability due to dysregulated host response is a life-threatening condition requiring vasopressors and vital organ support. Hemoadsorption with Cytosorb has proven to be effective in reducing cytokines and..

Read More
thumbnail
0 comment

Factor XI Inhibition to Uncouple Thrombosis From Hemostasis: JACC Review Topic of the Week

Abstract Hemostasis and thrombosis are believed to be so intricately linked that any strategies that reduce thrombosis will have an inevitable impact on hemostasis. Consequently, bleeding is viewed as an unavoidable..

Read More
thumbnail
0 comment

Costs and consequences of acute kidney injury after cardiac surgery: A cohort study

Abstract Objectives  (AKI) is common after cardiac surgery. We quantified the mortality and costs of varying degrees of AKI using a population-based cohort in Alberta, Canada. Methods A cohort of..

Read More
thumbnail
0 comment

Amyloidosis

Amyloidosis is caused by an accumulation of abnormal protein, called amyloid deposits. If these build up in your body they can cause problems, depending on where in your body they..

Read More
thumbnail
0 comment

2021 ESC/EACTS Guidelines for the management of valvular heart disease: Developed by the Task Force for the management of valvular…

Preamble Guidelines summarize and evaluate available evidence with the aim of assisting health professionals in proposing the best management strategies for an individual patient with a given condition. Guidelines and..

Read More
thumbnail
0 comment

Anatomy of Mitral Valve Complex as Revealed by Non-Invasive Imaging: Pathological, Surgical and Interventional Implications

Abstract Knowledge of mitral valve (MV) anatomy has been accrued from anatomic specimens derived by cadavers, or from direct inspection during open heart surgery. However, today two-dimensional and three-dimensional transthoracic..

Read More
thumbnail
0 comment

Comparison of stored red blood cell washing techniques for priming extracorporeal circuits

Abstract Background: The aim of this study was to compare three different blood washing techniques and describe the differences for the composition of the washed red blood cells (RBC). Methods:..

Read More
thumbnail
0 comment

How to Turn It Down: The Evidence and Opinions Behind Adult Venoarterial Extracorporeal Membrane Oxygenation Weaning

Abstract Adequate and durable recovery in patients supported with venoarterial (VA) extracorporeal membrane oxygenation (ECMO) can be challenging to predict. Extracorporeal membrane oxygenation weaning is the process by which the..

Read More
thumbnail
0 comment

Virtual reality device training for extracorporeal membrane oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is a last resort therapy for patients with terminal respiratory failure. In the current worldwide surge of critically ill patients with novel coronavirus disease (COVID-19),..

Read More
thumbnail
0 comment

ECMO During a Pandemic: A COVID-19 Quality Improvement Process

Abstract Extracorporeal membrane oxygenation is a modified form of cardiopulmonary bypass and a complex adult critical care therapy. No evidence appears to exist on sustaining relevant quality nursing standards during..

Read More
thumbnail
0 comment

Priming solution for neonatal and pediatric cardiopulmonary bypass

Abstract The Priming volume of the oxygenators has been reduced by 75% during the last two decades and it is now possible to go safely on bypass with a priming..

Read More
thumbnail
0 comment

Why is saline so acidic (and does it really matter?)

Abstract Commercial 0.9% saline solution for infusion has a pH around 5.5. There are many reasons for this acidity, some of them still obscure. It is also true that infusion..

Read More
thumbnail
0 comment

Tricuspid valve

Learning points: The tricuspid valve is the largest of the heart valves . Its anatomical structure is complex and constituted of the 3 leaflets, the annulus, the chordae, the papillary..

Read More
thumbnail
0 comment

Huge Right Ventricle mass

Patient with severe dyspnea and chest pain undergone TTE and CMR which confirmed presence of huge RV mass with relation to both LV as well as RV undergone mass resection..

Read More
thumbnail
0 comment

Impact of minimal invasive extracorporeal circulation on perioperative intravenous fluid management in coronary artery bypass surgery

Abstract Objective: Compare the use of blood products and intravenous fluid management in patients scheduled for coronary artery bypass surgery and randomized to minimal invasive extracorporeal circulation (MiECC) and conventional..

Read More
thumbnail
0 comment

Arterial diseases imaging

Acquired diseases Aortic aneurysm     Prof. Mamdouh Mahfouz      

Read More
thumbnail
0 comment

Noninvasive Urine Oxygen Monitoring and the Risk of Acute Kidney Injury in Cardiac Surgery

Abstract Background Acute kidney injury (AKI) is a common complication of cardiac surgery. An intraoperative monitor of kidney perfusion is needed to identify patients at risk for AKI. The authors..

Read More
thumbnail
0 comment

Sequestration of Dexmedetomidine in Ex Vivo Cardiopulmonary Bypass Circuits

Abstract Dexmedetomidine (DEX) is a sedative used in combination with other drugs in neonates and infants undergoing cardiac surgery using cardiopulmonary bypass (CPB). This study aimed to evaluate the disposition..

Read More
thumbnail
0 comment

Evaluation of Seizure Risk in Infants After Cardiopulmonary Bypass in the Absence of Deep Hypothermic Cardiac Arrest

Abstract Background Guidelines recommend evaluation for electrographic seizures in neonates and children at risk, including after cardiopulmonary bypass (CPB). Although initial research using screening electroencephalograms (EEGs) in infants after CPB..

Read More
thumbnail
0 comment

Reversal of renal tissue hypoxia during experimental cardiopulmonary bypass in sheep by increased pump flow and arterial pressure

Abstract Aim Renal tissue hypoxia during cardiopulmonary bypass could contribute to the pathophysiology of acute kidney injury. We tested whether renal tissue hypoxia can be alleviated during cardiopulmonary bypass by..

Read More