Pediatric

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The Efficacy, Safety and Cost-Effectiveness of Intra-Operative Cell Salvage in…

Abstract Objective: Intra-operative cell salvage (CS) was reported to be ineffective, safe and not cost-effective in low-bleeding-risk cardiac surgery with cardiopulmonary bypass (CPB), but studies in high-bleeding-risk cardiac surgery are limited. The objective of this study is to evaluate the efficacy, safety and cost-effectiveness of intra-operative CS in high-bleeding-risk cardiac surgery..

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Post-Operative Bleeding Risk Stratification in Cardiac Pulmonary Bypass Patients Using…

Abstract The prediction of bleeding risk in cardiopulmonary bypass (CPB) patients plays a vital role in their postoperative management. Therefore, an artificial neural network (ANN) to analyze intra-operative laboratory data to predict postoperative bleeding was set up. The JustNN software (Neural Planner Software, Cheshire, England) was used. This ANN was..

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Hemolytic characteristics of three suctioning systems for use with a…

Abstract Introduction: We have been developing a closed-circuit cardiopulmonary bypass (CPB) system (“Dihead CPB”) for application during coronary artery bypass grafting (CABG) and valve surgery. To strive for minimal hemolysis during Dihead CPB, we compared the hemolysis caused by three different suction systems and performed a clinical study with the..

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Developments in Pediatric Ventricular Assist Device Support

Abstract Mechanical support devices have revolutionized the management of circulatory failure. This has been met by a dramatic increase in ventricular assist device (VAD) utilization in children over the last two decades. Previous wide gaps in experience and knowledge have significantly narrowed in the recent years. As we continue to..

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Establishing an ECMO program in a developing country: challenges and…

Abstract Aim: The ECMO (extracorporeal membrane oxygenation) Program at the American University of Beirut Medical Center was established in November 2015 as the first program serving adult and pediatric population in a low-resource setting. The aim of the study is to describe the challenges faced during the establishment of the..

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Aprotinin versus tranexamic acid in children undergoing cardiac surgery: an…

Abstract OBJECTIVES: The upcoming release of aprotinin in paediatric cardiac surgery prompted a re-evaluation of its use in comparison to tranexamic acid (TXA) focusing on their effect on exposure to blood transfusions as well as severe postoperative morbidity or mortality. METHODS: This retrospective study was conducted in a tertiary children..

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Hemolytic characteristics of three suctioning systems for use with a…

Abstract Introduction: We have been developing a closed-circuit cardiopulmonary bypass (CPB) system (“Dihead CPB”) for application during coronary artery bypass grafting (CABG) and valve surgery. To strive for minimal hemolysis during Dihead CPB, we compared the hemolysis caused by three different suction systems and performed a clinical study with the..

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Anticoagulation during ECMO in neonatal and paediatric patients

Abstract  (ECMO) is a form of  (ECLS) which is used frequently in the paediatric and neonatal setting to support either the pulmonary, or both the pulmonary and . Management of ECMO requires the use of systemic  to prevent patient and circuit based , which in turn increases the risk of haemorrhage. A number of ,..

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Correlation of cardiopulmonary bypass duration with acute renal failure after…

Abstract Objectives Prolonged  (CPB) is recognized as a risk factor for  (ARF), but the dose effect of time on bypass is unknown. We therefore examined the risk of ARF associated with increasing CPB time stratified by preoperative renal function. Methods A retrospective analysis was performed on 3889 patients undergoing cardiac surgery on..

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Acute kidney injury and fluid overload in infants and children…

Abstract Acute kidney injury is a common and serious complication after congenital heart surgery, particularly among infants. This comorbidity has been independently associated with adverse outcomes including an increase in mortality. Postoperative acute kidney injury has a complex pathophysiology with many risk factors, and therefore no single medication or therapy..

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