Pediatric

Perfusfind S.L.

Abstract Background Cardiac surgery with cardiopulmonary bypass (CPB) is known to contribute towards the incidence of acute kidney injury (AKI) and peri-operative morbidity and mortality. There are several patient, anaesthetic and surgical factors that contribute to its occurrence. It is imperative to know the profile of a patient who is..

Perfusfind S.L.

THE CURRENT pandemic owing to coronavirus disease 2019 (COVID-19) has been associated in about 10% to 15% of cases with severe clinical presentations that require admission to hospital.  In the cohort of patients with severe COVID-19, the risks of admission to an intensive care unit are high owing to critical..

Perfusfind S.L.

Abstract Background Coronavirus disease 2019 (COVID-19) remains a worldwide pandemic with a high mortality rate among patients requiring mechanical ventilation. The limited data that exist regarding the utility of extracorporeal membrane oxygenation (ECMO) in these critically ill patients show poor overall outcomes. This report describes our institutional practice regarding the..

Perfusfind S.L.

Abstract Importance  Extracorporeal membrane oxygenation (ECMO) is a form of advanced life support that may be used in children with refractory respiratory or cardiac failure. While it is required infrequently, in the US, ECMO is used to support childhood respiratory failure as often as children receive kidney or heart transplants. ECMO..

Perfusfind S.L.

 A team at Duke Health has performed what is believed to be the world’s first partial heart transplant, with the living arteries and valves from a freshly donated heart fused onto a patient’s existing heart. The goal is to allow the valves to grow with the pediatric patient over time,..

Perfusfind S.L.

Abstract Cardiopulmonary bypass (CPB) in infants is associated with morbidity due to systemic inflammatory response syndrome (SIRS). Strategies to mitigate SIRS include management of perfusion temperature, hemodilution, circuit miniaturization, and biocompatibility. Traditionally, perfusion parameters have been based on body weight. However, intraoperative monitoring of systemic and cerebral metabolic parameters suggest..

Perfusfind S.L.

Abstract The long-term neurodevelopmental outcome has been a great concern for cardiac surgeons although it is still unclear. There are some risks regarding the neurological and neuropsychological deficits before, during and after cardiovascular surgery. Current status of brain protection during congenital heart surgery could be reported. The incidence of neurologic..

Perfusfind S.L.

Abstract The convenience offered by a single-dose cardioplegia strategy is the avoidance of interruption of the flow of surgery and, more importantly, a significant reduction in the cross-clamp time. del Nido cardioplegia is an extracellular cardioplegic solution which serves these purposes and has been used successfully in pediatric cardiac surgery...

Perfusfind S.L.

Abstract Background  is one of the main natural  inhibitors. It is potentiated by heparin, and may be a key component of heparin response, particularly in infants aged <1 year. We sought to determine the impact of baseline antithrombin activity on response to heparin and  generation during  (CPB). Methods Secondary analysis was performed using  analyses, which..

Perfusfind S.L.

Abstract Background: The use of two diagnostic criteria in the current literature has led to some degree of ambiguity in the precise diagnosis of acute kidney injury in pediatric patients undergoing surgery for congenital heart disease. This study aims to determine which criteria is the most accurate diagnostic indicator of..