Monthly Archives: January 2025

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Global Survey of Extracorporeal Membrane Oxygenation Transport Programs: Variability in Team Composition, Training, and Capabilities

Abstract Extracorporeal membrane oxygenation (ECMO) is a form of cardiopulmonary support associated with improved survival in severe respiratory failure and refractory cardiac arrest. Extracorporeal membrane oxygenation is highly specialized and..

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Prognostic scores of extracorporeal membrane oxygenation: a scoping review

Abstract BACKGROUND: Extracorporeal membrane oxygenation (ECMO) is an effective measure for saving the lives of critically ill patients. Prompt identification of the risk factors for mortality among patients receiving ECMO and..

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Comparison of Two Activated Clotting Time Targets During Cardiac Surgery With Cardiopulmonary Bypass: A Prospective Multicenter Randomized Controlled Trial

Abstract Objectives The present study was designed to investigate the equivalence of two target activated clotting time (ACT) values with regard to packed red blood cell (PRBC) transfusion in patients..

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Extracorporeal Cardiopulmonary Resuscitation: Reviewing the Evidence and Exploring Its Equitable Implementation in the UK National Health Service

Abstract Cardiac arrest outcomes remain historically poor with survival to hospital discharge less than 2.2% in the UK (). Refractory cardiac arrest is characterized by a persistent loss of circulation..

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High vasoactive-inotropic score is associated with poor outcomes in patients undergoing coronary artery bypass grafting: A systematic review and meta-analysis

Abstract Background Vasoactive-inotropic score (VIS) has been previously utilized as one of the predictors in open heart procedures postoperatively, but its association with poor outcomes in patients who underwent coronary..

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Selective visceral perfusion in thoracoabdominal aortic surgery: optimal flow rate in a porcine model

Abstract To determine the optimal perfusion volume for the celiac artery (CA) and superior mesenteric artery (SMA) in a porcine model. Fifteen Yorkshire pigs (46.7 ± 5.2 kg) underwent selective CA and..

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Tolerating cardiovascular health disparities is a failure of science and society

Abstract Cardiovascular disease is responsible for  of all deaths in Europe. Decades of research and investment have achieved impressive declines in overall cardiovascular disease mortality, yet this progress hides a persistent..

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Does normothermic regional perfusion harm donors after circulatory death?

Abstract Normothermic regional perfusion during controlled donation after circulatory death has emerged as a means to increase the number and viability of organs available for transplant. Because normothermic regional perfusion..

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Re-evaluating the association between thrombocytopenia and bleeding in extracorporeal membrane oxygenation (ECMO)

Abstract Objectives The platelet trigger at which to transfuse platelets to prevent bleeding complications in patients supported with extracorporeal membrane oxygenation (ECMO) is unclear. We aimed to elucidate the association..

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Association between intraoperative lactate levels and acute kidney injury after on-pump cardiac surgery: a retrospective cohort study across two centers

Abstract Background Hyperlactatemia and acute kidney injury (AKI) represent significant perioperative complications in cardiac surgery. This study investigated their relationship by analyzing multiple lactate parameters during on-pump cardiac procedures. Methods..

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Impact of Preoperative Extracorporeal Membrane Oxygenation Use on Lung Transplant Outcomes

Abstract Background  (ECMO) may be used to support critically ill patients before . The relationship between preoperative venoarterial and venovenous ECMO and their relationship with  indications remain poorly elucidated. Methods This study..

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Temporary Mechanical Circulatory Support in Cardiogenic Shock: Executive Summary of the Joint Consensus Reports of the PeriOperative Quality Initiative and…

Abstract Background The identification, triage, and management of cardiogenic shock (CS) are complex and resource intensive, particularly given the recent surge in the use of temporary mechanical circulatory support (tMCS)..

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Malperfusion, Malperfusion Syndrome, and Mesenteric Ischemia in Aortic Dissection

Abstract Aortic malperfusion occurs in a significant percentage of patients with acute , and causes , the clinical entity defined by end organ , in 10–33% of patients. Malperfusion syndrome can be rapidly..

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The role of the modified Glasgow prognostic score in predicting postoperative mortality following open-heart surgery

Abstract PurposeThe Modified Glasgow Prognostic Score is an inflammation-based index utilizing C-reactive protein and albumin levels. It has been investigated in various diseases such as cancer, heart failure, and myocardial..

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Pulmonary arterial hypertension in neonates and children post open-heart surgery: assessment and management including extracorporeal membrane oxygenation (ECMO) — a…

Abstract Background Congenital heart disease (CHD) that requires heart surgery is common. Severe postoperative pulmonary hypertension (PH) occurs in 2% of cardiac procedures and is associated with high morbidity and..

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Experimental Comparison of Esmolol- and Blood-Based Cardioplegia for Long Aortic Clamping Times

Abstract Objectives After cardiac surgery, long aortic clamping times and extracorporeal circulation times are associated with worse outcomes. This study compares hemodynamic performance, myocardial metabolism, and ultrastructural preservation in rat..

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Aortic Balloon Occlusion in Circulatory Determination of Death Donors Undergoing Abdominal Normothermic Regional Perfusion? Think High!

Abstract Normothermic regional perfusion (NRP) is a strategy of postmortem reperfusion with warm oxygenated blood of a portion of the body applied in donors undergoing circulatory determination of death (DCDDs)...

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Venovenous Extracorporeal Membrane Oxygenation Cannulation by Intensivists and Surgeons: A Single-Center Retrospective Noninferiority Analysis of Complications and Outcomes From 2018…

Abstract Objectives:  To evaluate the safety and efficacy of venovenous extracorporeal membrane oxygenation (ECMO) cannulation by nonsurgeon intensivists (critical care medicine intensivists [CCM]) compared with cardiothoracic surgeons (CTS). Design:  Retrospective,..

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Complement activation by the artificial surface of cardiopulmonary bypass is a persistent clinical problem

Abstract Activation of the alternative complement pathway by artificial extracorporeal surfaces is relevant to several clinical applications such as cardiac surgery with cardiopulmonary bypass (CPB), thoracic organ transplantation and hemodialysis...

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Stepwise Description of En-bloc Heart–Liver Procurement

En-bloc Heart–Liver Procurement 1. Exposure and Preparation The procedure begins with a midline sternotomy extended into a midline laparotomy, allowing simultaneous access to both the thoracic and abdominal cavities. The..

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Review of Current Normothermic Regional Perfusion Practice in Pediatric Cardiac Donation

Abstract Background Cardiac allotransplantation is the optimal treatment for end-stage heart failure. However, organ supply remains the principal issue affecting patients. Pediatric patients present unique challenges resulting in long wait-list..

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Innovative strategies in coagulation management for cardiothoracic surgery: a narrative review of pharmacological and nonpharmacological approaches

Abstract The challenging management of coagulation in cardiothoracic surgery requires a multifaceted approach. The use of pharmacological interventions such as tranexamic acid, heparin, and aprotinin minimizes bleeding but increases the..

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Blood Pump Surface Roughness: Hemocompatibility and Machining Optimization

Abstract Blood compatibility, defined as a material’s ability to maintain blood flow without inducing coagulation or hemolysis, was investigated through surface roughness optimization in blood pump flow channels. This study..

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Postoperative Infectious Pneumonia in Cardiothoracic Surgery: A Systematic Review and Meta-Analysis

Abstract Background Postoperative infectious pneumonia (PIP) is a common and serious complication following cardiothoracic surgery, including coronary artery bypass grafting (CABG), valve interventions, and thoracic oncologic procedures. It is associated..

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Modified cardiopulmonary bypass circuit for transcatheter aortic valve implantation and emergent cardiac surgery

Abstract Transcatheter aortic valve implantation (TAVI) has revolutionized the treatment of severe aortic stenosis in high-risk patients, offering a minimally invasive alternative to open-heart surgery. However, complications such as hemodynamic..

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Fluid management of cardiopulmonary bypass during pulmonary endarterectomy for CTEPH patients impacts perioperative outcome

Abstract Background Pulmonary endarterectomy (PEA) using deep hypothermic circulatory arrest (DHCA) and cardiopulmonary bypass (CPB) is the preferred treatment for chronic thromboembolic pulmonary hypertension (CTEPH). Crystalloid priming solutions cause hemodilution..

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Hospital Anxiety and Depression Scale in patients undergoing extracorporeal circulation: an Italian cross-sectional study

Abstract Globally, cardiovascular diseases (CVDs) are the major leading cause of death. Medical literature shows an association between CVDs and depressive symptoms, anxiety, low social support, and optimism. Also, cardiac..

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Intraoperative Cell Salvage in Oncologic Surgery: A Comprehensive Review

Abstract Intraoperative cell salvage (ICS) is a blood conservation technique utilized in major surgery, yet its application in oncologic procedures remains debated. Concerns persist about the theoretical risk of metastasis..

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Protruding Objects in the Membrane Lung Outlet May Increase Thrombogenicity: Fluid Dynamical Insights

Abstract Thrombosis in extracorporeal membrane oxygenation (ECMO) circuit components remains a challenge. Besides blood state and surface properties, flow plays a critical role in hemostasis. In this work, we aimed..

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In-Hospital Outcomes and Readmissions in High-Risk Pulmonary Embolism Patients Requiring Extracorporeal Membrane Oxygenation Support

Abstract There are limited data on the use of extracorporeal membrane oxygenation (ECMO) in high-risk pulmonary embolism (PE) patients. We analyzed the use of ECMO in high-risk PE patients (defined..

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