Stichworte Archiv: albumin

Perfusfind S.L.

Abstract Importance  Acute kidney injury (AKI) after cardiac surgery is a common and serious complication. Protein loading appears nephroprotective; thus, continuous hyperoncotic albumin infusion may impact AKI following high-risk cardiac surgery...

Perfusfind S.L.

Abstract Human serum albumin (HSA) is a non-glycosylated, negatively charged, single-chain polypeptide composed of 585 amino acid residues with a relative molecular mass of 66.438 kD. It is synthesized by..

Perfusfind S.L.

Abstract Objective To compare the effects of fluid bolus therapy (FBT) with 20% albumin to crystalloid FBT on the incidence of cardiac surgery–associated acute kidney injury (CSA-AKI) and its severity..

Perfusfind S.L.

Abstract Objectives Cardiac surgery–associated acute kidney injury (CSA-AKI) is a common complication with high morbidity and mortality. This study was designed to determine whether adding human albumin to the cardiopulmonary..

Perfusfind S.L.

Abstract Objectives Compare hemodynamics between 4% albumin and Ringer's acetate. Design Exploratory analysis of the double-blind randomized ALBumin In Cardiac Surgery trial. Setting Single-center study in Helsinki University Hospital. Participants..

Perfusfind S.L.

Abstract Purpose After cardiac surgery, fluid bolus therapy (FBT) with 20% human albumin may facilitate less fluid and vasopressor administration than FBT with crystalloids. We aimed to determine whether, after..

Perfusfind S.L.

Abstract Background Albumin is used commonly across a wide range of clinical settings to improve hemodynamics, to facilitate fluid removal, and to manage complications of cirrhosis. The International Collaboration for..

Perfusfind S.L.

Abstract Purpose Nowadays, it is largely accepted that albumin should not be used in hypoalbuminemia or for nutritional purpose. The most discussed indication of albumin at present is the resuscitation..

Perfusfind S.L.

Abstract Background Albumin continues to be used routinely by cardiac anaesthesiologists perioperatively despite lack of evidence for improved outcomes. The Multicenter Perioperative Outcomes Group (MPOG) data ranked our institution as one..

Perfusfind S.L.

Abstract Background In on-pump cardiac surgery, the albumin priming strategy could maintain colloid osmotic pressure better than crystalloid solutions and reduce excessive perioperative fluid balance. However, a high-quality meta-analysis is..

Perfusfind S.L.

Abstract Background Intravenous albumin is commonly utilised in cardiovascular surgery for priming of the cardiopulmonary bypass circuit, volume replacement, or both, although the evidence to support this practice is uncertain...

Perfusfind S.L.

Abstract Purpose The integrity of the endothelial glycocalyx (EG), a critical player in vascular homeostasis, reportedly influences the outcomes of critically ill patients. We investigated the effect of 5% albumin,..

Perfusfind S.L.

Abstract Objectives To assess the efficacy and safety of albumin as pump priming fluid in cardiac surgery. Design Meta-analysis of randomized controlled trials. Setting Each study was conducted in a..

Perfusfind S.L.

Abstract Objectives To study the quantitative potency of plasma albumin on cardioprotection in terms of creatinine kinase-myocardial band mass (CK-MBm) in on-pump cardiac surgery. Design Post hoc analysis of a..

Perfusfind S.L.

Abstract Background In the recent ALBICS (ALBumin In Cardiac Surgery) trial, 4% albumin used for  priming and volume replacement increased perioperative bleeding compared with . In the present exploratory study, albumin-related bleeding..

Perfusfind S.L.

Abstract Hemodynamic instability in postresuscitation syndrome worsens survival and neurological outcomes. Venoarterial extracorporeal membrane oxygenation (VA ECMO) for refractory cardiac arrest might improve outcomes. Hemodynamical support under VA ECMO relies..

Perfusfind S.L.

Abstract Introduction:  Acute kidney injury (AKI) after cardiac surgery is a common and serious postoperative complication and is associated with an increased risk of mortality, morbidity, length of hospital stay,..

Perfusfind S.L.

Abstract Albumin, which is a 65-kDa liver-synthesized protein, accounts for nearly 50% of total plasma protein and contributes to approximately 80% of intravascular oncotic pressure. Albumin helps maintain microvascular integrity,..

Perfusfind S.L.

Abstract Objectives: To investigate the effect of albumin exposure in ICU after cardiac surgery on hospital mortality, complications, and costs. Design: A retrospective, single-center cohort study with economic evaluation. Setting:..

Perfusfind S.L.

Abstract Albumin has been used in clinical medicine for more than seven decades. At the time of circulation and deairing of asanguineous primes during CPB, many programs will first remove..

Perfusfind S.L.

Abstract Albumin solution was no better than Ringer acetate at reducing complications from cardiac surgery with cardiopulmonary bypass in a randomized clinical trial. Likelihood of at least one major adverse..

Perfusfind S.L.

Abstract Importance  In cardiac surgery, albumin solution may maintain hemodynamics better than crystalloids and reduce the decrease in platelet count and excessive fluid balance, but randomized trials are needed to compare..

Perfusfind S.L.

Abstract Objectives To determine whether the early use of  after cardiac surgery in the first 24 hours in the intensive care unit (ICU) is associated with reduced mortality. Design A single-center..

Perfusfind S.L.

Abstract Albumin plays an important role in critical care as a prognostic marker and therapy. However, the use of human albumin solution (HAS) has varied over time due to the..

Perfusfind S.L.

Abstract There is limited evidence as to the pharmacokinetic changes expected in adults with extracorporeal technologies. Drugs may be taken up by various components of the cardiopulmonary bypass circuit itself...

Perfusfind S.L.

Abstract Background Fluid administration is a key tool in the maintenance of normovolemia in patients with cardiac surgery. The trials that evaluated the safety of 6% hydroxyethyl starch (HES) 130/0.4..

Perfusfind S.L.

Abstract Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) supports patients suffering from refractory cardiogenic shock. Thromboembolic complications (TeC) are common in VA-ECMO patients and are associated with increased morbidity and mortality. Valid..

Perfusfind S.L.

Abstract There is limited evidence as to the pharmacokinetic changes expected in adults with extracorporeal technologies. Drugs may be taken up by various components of the cardiopulmonary bypass circuit itself...

Perfusfind S.L.

Abstract Objective To evaluate the current practice of perioperative fluid management in cardiac surgery patients. Design Multiple choice survey with 26 questions about existing practice of perioperative fluid management in..

Perfusfind S.L.

Abstract Background Hypoalbuminemia may increase the risk of acute kidney injury (AKI). The authors investigated whether the immediate preoperative administration of 20% albumin solution affects the incidence of AKI after..