Use of CytoSorb in a pediatric patient with septic shock in the setting of a non-controlled infectious focus
The case study reports on a 16-year-old girl, who presented to the hospital with syncope and fever (39°C), tachycardia, complaints of chest pain and coughing after fainting at home.
Use of CytoSorb in a pediatric patient with septic shock in the setting of a non-controlled infectious focus_compressed
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Jan 1, 1970
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Jan 1, 1970
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Jan 1, 1970
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Alteration in Indole Metabolites…
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Jan 1, 1970
Extracorporeal membrane oxygenation for…
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Jan 1, 1970
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Jan 1, 1970
Infectious diseases and infection…
Abstract As survival after ECMO improves and use of ECMO support increases in both pediatric and adult population, there is a need to focus on both the morbidities and complications..
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Jan 1, 1970
Optimal brain perfusion pressure…
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Jan 1, 1970
Over 3,000 Minimally Invasive…
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Jan 1, 1970
Conventional Cardiopulmonary Resuscitation Versus…
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Jan 1, 1970
Impaired cerebral autoregulation in…
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Jan 1, 1970
Effect of cardiopulmonary bypass…
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Jan 1, 1970
Minimally invasive cardiac surgery…
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Jan 1, 1970
Successful Management of a…
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Jan 1, 1970
Goal-directed Perfusion to Reduce…
Abstract Background Although goal-directed perfusion (GDP) during cardiopulmonary bypass (CPB) has been discussed extensively in adult studies, no pediatric indexed oxygen delivery (Do2i) thresholds are universally accepted, and no pediatric..
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Jan 1, 1970
Diagnosing Nosocomial Infections During…
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Jan 1, 1970
Cerebral Hemodynamic Monitoring via…
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Jan 1, 1970
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Jan 1, 1970
Prothrombotic Microvesicle Generation in…
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Jan 1, 1970
The Association Between Platelet…
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Jan 1, 1970
Comprehensive surgical technique for…
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Jan 1, 1970
Perioperative extracorporeal membrane oxygenation…
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Jan 1, 1970
Timing of venoarterial extracorporeal…
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Jan 1, 1970
Use of Inhaled Tranexamic…
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Jan 1, 1970
Racial and Sex Disparities…
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Neonatal venoarterial extracorporeal membrane…
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Pump‐controlled retrograde trial off…
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Trends in Cardiac Arrest…
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Jan 1, 1970
Urine biomarkers, acute kidney…
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Jan 1, 1970
Daily Surveillance Blood Cultures…
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Jan 1, 1970
Perioperative extracorporeal membrane oxygenation…
Abstract OBJECTIVES Extracorporeal membrane oxygenation (ECMO) can act as a bridge to recovery in both pre- and postoperative patients with transposition of the great arteries (TGA). However, literature on its..
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Jan 1, 1970
The first case of…
Abstract The mechanical circulatory support (MCS) for pediatric patients with severe acute heart failure and poor pulmonary conditions is challenging. Herein, we report the first pediatric case of successfully treated..
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Jan 1, 1970
Implementation of Bundled Interventions…
Abstract Pediatric patients undergoing cardiothoracic surgery are at increased risk for health care–associated infections, especially surgical site infections (SSIs). Delayed sternal closures are associated with prolonged lengths of stay and..
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Jan 1, 1970
Best Practices for Vessel…
Abstract Extracorporeal membrane oxygenation (ECMO) to support neonates and children with cardiopulmonary failure was first described in the 1970s, since which time its use has expanded to an increasingly complex..
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Jan 1, 1970
CO2 field-flooding devices offer…
Abstract Objective This study sought to evaluate the value of a CO2 field-flooding device in cardiopulmonary bypass (CPB) surgical procedures for congenital heart disease (CHD) performed via a right-side small incision..
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Jan 1, 1970
Development and validation of…
Abstract Background Timely recognition of perioperative red blood cell transfusion (PRT) risk is crucial for developing personalized blood management strategies in pediatric patients. In this study, we sought to construct..
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Jan 1, 1970
Extracorporeal membrane oxygenation for…
Abstract Objective We aimed to outline the experience with extracorporeal membrane oxygenation (ECMO) for respiratory and cardiac failure in neonates in our institution and compare our results with those from..
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Jan 1, 1970
Outcomes in Children Who…
Abstract Background Children who undergo cardiac surgery may require postcardiotomy extracorporeal membrane oxygenation (ECMO). Although morbidities are considerable, our understanding of outcome determinants is limited. We evaluated associations between patient..
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Jan 1, 1970
Early Use Experience of…
Abstract Veno-venous (VV) extracorporeal membrane oxygenation (ECMO) is associated with fewer neurological complications and decreased mortality compared to veno-arterial (VA) ECMO in neonatal respiratory failure. The Crescent right atrial (RA)..
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Jan 1, 1970
Randomized Trial of Pulsatile…
Abstract Background The study objective was to determine the impact of cardiopulmonary bypass perfusion modalities on cerebral hemodynamics and clinical outcomes in congenital cardiac surgery patients stratified by acyanotic versus..
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Jan 1, 1970
Application comparison of paediatric…
Abstract Background Reliable myocardial protection is essential for a good outcome after arterial switch operation. Patients and Methods We evaluated 56 neonates with arterial switch operation in this retrospective study...
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Jan 1, 1970
Short term outcomes of…
Abstract Background While the number of cardiac surgery programs in sub-Saharan Africa are increasing, it is still insufficient. With only 0.08 pediatric cardiac surgeons per million people, few cardiac centers..
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Jan 1, 1970
Preoperative Serum Ferritin Level…
Abstract Background Acute kidney injury (AKI) is a significant complication in pediatric patients undergoing cardiac surgery. Iron metabolism-related indicators such as ferritin may predict AKI after adult cardiac surgery. However, it..
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Jan 1, 1970
Using artificial intelligence to…
Abstract Introduction Congenital heart disease (CHD) represents the most common group of congenital anomalies, constitutes a significant contributor to the burden of non-communicable diseases, highlighting the critical need for improved..
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Jan 1, 1970
Factors associated with activated…
Abstract Introduction The recently recommended activated clotting time (ACT) to be maintained at the initiation of and during cardiopulmonary bypass (CPB) is ≥480 s. However, the post-unfractionated heparin (UFH) administration ACT..
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Jan 1, 1970
A randomized study on…
Abstract Background The aim of this study is to assess the impact of optimized modified ultrafiltration (OMUF) on the physiological parameters of infants and children undergoing cardiopulmonary bypass (CPB). Methods..
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Jan 1, 1970
“Extracorporeal membrane oxygenation outcomes…
Abstract Multisystem inflammatory disease in childhood (MIS-C) is a novel pediatric syndrome after a COVID-19 infection that causes systemic injury, with potential life-threatening hemodynamic compromise requiring Extracorporeal Membrane Oxygenation (ECMO)..
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Jan 1, 1970
Unifocalization of Major Aortopulmonary…
Abstract Background. Major aortopulmonary collateral arteries (MAPCAs) are rare remnants of pulmonary circulation embryological development usually associated with complex congenital anomalies of the right ventricular outflow tract and pulmonary arteries...
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Jan 1, 1970
Cerebral air embolism in…
Abstract Objective Cerebral air embolism during Cardio-Pulmonary Bypass is a severe complication with significant neurological risks. We present six pediatric cases, detailing their presentation, management, and outcomes. The discussion reviews..
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Jan 1, 1970
Bedside repositioning of a…
Abstract Background: Although the Avalon Elite bi-caval dual lumen catheter for veno-venous extracorporeal membranous oxygenation (ECMO) has many advantages, it requires precise positioning and dislodgement is common. Case presentation: A 2-year-old male..
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Jan 1, 1970
Association Between Arterial Hyperoxia…
Abstract BACKGROUND: In patients receiving extracorporeal membrane oxygenation (ECMO) support, the association between arterial hyperoxia and outcomes is unclear. We performed a systematic review and meta-analysis to determine the association..
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Jan 1, 1970
Pre-operative transcranial Doppler ultrasound…
Abstract Children requiring veno-arterial extracorporeal membrane oxygenation (VA ECMO) or cardiac surgery often undergo cervical cannulation or carotid artery clamping, which can interrupt cerebral circulation. Inadequate collateral flow through the..
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Jan 1, 1970
Cerebral Protection in Pediatric…
Abstract Cardiac surgery, both adult and pediatric, has developed very rapidly and impressively over the past 7 decades. Pediatric cardiac surgery, in particular, has revolutionized the management of babies born..
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Jan 1, 1970
Minimizing Acute Kidney Injury…
Abstract Background Acute kidney injury (AKI) poses a significant challenge in pediatric cardiac surgery, having a profound impact on patient morbidity and mortality. This study aims to determine the incidence..
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Jan 1, 1970
The association between changes…
Abstract Objective To investigate whether changes in cerebrovascular hemodynamic parameters during extracorporeal membrane oxygenation (ECMO) treatment in neonates are associated with the occurrence of cerebrovascular complications. Methods This study selected..
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Jan 1, 1970
The early decline in…
Abstract Introduction The impact of non heparin-induced thrombocytopenia on the clinical outcomes for pediatric cardiac surgery patients who required veno-arterial extracorporeal membrane support (VA-ECMO) for failure to wean from cardiopulmonary..
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Jan 1, 1970
Hemostatic Outcome Definitions in…
Abstract Objectives: To determine if a priori standardization of outcome hemostatic definitions alone was adequate to enable useful comparison between two cohorts of pediatric extracorporeal membrane oxygenation (ECMO) patients, managed..
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Jan 1, 1970
Prolonged Extracorporeal Circulation Leads…
Abstract Congenital heart defects (CHDs) are one of the most common congenital malformations and often require heart surgery with cardiopulmonary bypass (CPB). Children undergoing cardiac surgery with CPB are especially..
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Jan 1, 1970
Hyperlactataemia Following Crystalloid Cardiopulmonary…
Abstract Background: Various mechanisms leading to early hyperlactataemia post-cardiac surgery have been postulated. Specifically, in the paediatric population, benign early hyperlactataemia may be associated with crystalloid priming in the cardiopulmonary..
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Jan 1, 1970
Oxygen Delivery During Cardiopulmonary…
Abstract Objective This study was designed to investigate the distribution of nadir oxygen delivery (DO2), mean DO2, and area under ideal DO2 (AUiDO2) among categorized age groups of pediatric patients and..
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Jan 1, 1970
Association between plasma-free haemoglobin…
Abstract Background Acute kidney injury (AKI) is a common complication among patients requiring cardiopulmonary bypass (CPB) during paediatric cardiac surgery. Plasma-free haemoglobin (PFH) produced by haemolysis during CPB contributes to..
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Jan 1, 1970
Outcomes of protocol-based management…
Abstract Background: Extracorporeal membrane oxygenation (ECMO) is a vital mechanical circulatory support used with increasing frequency in complex congenital cardiac surgeries. This study evaluated the outcomes of a protocol-based venoarterial..
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Jan 1, 1970
Prospective Randomized Pilot Study…
Abstract Objectives: To test feasibility of a randomized controlled trial (RCT) with an endpoint of time at goal anticoagulation in children on extracorporeal membrane oxygenation (ECMO) randomized to receive bivalirudin..
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Jan 1, 1970
Concurrent use of continuous…
Abstract Extracorporeal membrane oxygenation (ECMO) provides temporary cardiorespiratory support for neonatal, pediatric, and adult patients when traditional management has failed. This lifesaving therapy has intrinsic risks, including the development of..
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Jan 1, 1970
Survival and Neurocognitive Outcomes…
Abstract This referral center prospective inception cohort study included 84 consecutive children having extracorporeal membrane oxygenation (ECMO) for noncardiac illness indications at the age of less than 6 years from..
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Jan 1, 1970
ACTION-ARC Pediatric and Adult…
Abstract Adverse events (AEs) experienced by children and adults with congenital heart disease (CHD) on ventricular assist devices (VADs) are sometimes unique to these populations. The Advanced Cardiac Therapies Improving..
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Jan 1, 1970
Unraveling the Blood Biomaterial…
Abstract Pediatric extracorporeal membrane oxygenation (ECMO) provides lifesaving cardiopulmonary support for patients with a multitude of clinical diagnoses, resulting from cardiac and/or respiratory failure refractory to conventional supports (). The..
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Jan 1, 1970
Perioperative paediatric patient blood…
Abstract Patient blood management (PBM) encompasses implementing multimodal evidence-based strategies to screen, diagnose, and properly treat anaemia and coagulopathies using goal-directed therapy while minimising bleeding. The aim of PBM is..
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Jan 1, 1970
Postoperative bleeding outcome of…
Abstract Introduction Bleeding after cardiac surgeries holds risk of mortality and morbidity in pediatrics. This systematic review aimed to evaluate postoperative blood loss and blood transfusion requirements for pediatric patients..
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Jan 1, 1970
Hemostatic derangements associated with…
Abstract Background Understanding of the hemostatic and complement alterations associated with cardiopulmonary bypass (CPB) in pediatric patients and the impact of these alterations on outcome is limited. Objectives The present..
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Jan 1, 1970
Prophylactic corticosteroids for infants…
Abstract Background Prophylactic corticosteroids have been widely used to mitigate the inflammatory response induced by cardiopulmonary bypass (CPB). However, the impact of this treatment on clinically important outcomes in infants..
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Jan 1, 1970
Cardiopulmonary bypass in a…
Abstract The safe use of cardiopulmonary bypass (CPB) relies upon the ability to administer, monitor, and reverse anticoagulation. Although rare, the factor XII deficient patient creates a challenge for the..
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Jan 1, 1970
Usefulness of bilateral cerebral…
Abstract Background We report a pediatric case where bilateral regional oxygen saturation (rSO2) measurements were useful in determining the selective cerebral perfusion (SCP) flow rate. Case presentation A 9-year-old Japanese..
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Jan 1, 1970
Thromboelastography-guided Intraoperative Platelet Transfusion…
Abstract Background Postoperative bleeding is associated with significant resource use and is an important contributor to other major adverse events in pediatric patients undergoing complex cardiac surgical procedures. Thromboelastography (TEG;..
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Jan 1, 1970
Outcomes in peripheral right…
Abstract Introduction The Protek Duo (PtD) dual lumen, single cannula was developed as a percutaneous system for temporary mechanical support, inserted through the internal jugular vein (IJ) for both atrial..
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Jan 1, 1970
Sanguineous cardiopulmonary bypass prime…
Abstract Background The inflammatory response to cardiopulmonary bypass (CPB) in pediatric patients remains an unresolved challenge. Sanguineous CPB prime, composed of allogenic blood products, is one potentially important stimulus. This..
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Jan 1, 1970
Predictors of Neurologic Complications…
Abstract Extracorporeal membrane oxygenation (ECMO) has emerged as an important intervention for children both preceding and following cardiac surgery. There is a notable lack of comprehensive information regarding neurodevelopmental outcomes...
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Jan 1, 1970
Association Between Persistent Hypothermia…
Abstract IMPORTANCE: Persistent hypothermia after cardiopulmonary bypass (CPB) in neonates with congenital heart defects (CHD) has been historically considered benign despite lack of evidence on its prognostic significance. OBJECTIVES: Examine..
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Jan 1, 1970
Unraveling the Blood Biomaterial…
Abstract Pediatric extracorporeal membrane oxygenation (ECMO) provides lifesaving cardiopulmonary support for patients with a multitude of clinical diagnoses, resulting from cardiac and/or respiratory failure refractory to conventional supports. The utilization..
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Jan 1, 1970
Reducing the prime cardiopulmonary…
Abstract Introduction Despite technological advances, the use of homologous blood to prime the cardiopulmonary bypass (CPB) circuits of infants under 10 kg remains common. However, such rapid massive transfusion may increase..
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Jan 1, 1970
Association Between Tidal Volume…
Abstract Mechanical ventilation (MV) strategies in children on extracorporeal membrane oxygenation (ECMO) have not been studied much and the ventilatory parameters to avoid greater lung damage are still unclear. Our..
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Jan 1, 1970
Gut Microbiome in Children…
Abstract The gut microbiome of infants with congenital heart disease (CHD) undergoing cardiopulmonary bypass surgery (CPB) is at risk of profound alteration. The aim of this study was to examine..
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Jan 1, 1970
Anomalous Left Coronary Artery…
Abstract Anomalous left coronary artery from the pulmonary artery (ALCAPA) is an uncommon life-threatening congenital heart defect that occurs mostly as an isolated lesion. It is very rarely associated with..
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Jan 1, 1970
Temperature and Neurologic Outcomes…
Abstract Background There is significant variability in postoperative neurological injury rates in patients with , with early injuries impacting long-term neurodevelopmental outcomes; therefore, there is an urgent need for identifying effective..
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Jan 1, 1970
Multiple Pediatric Extracorporeal Membrane…
Abstract Despite high mortality rates, pediatric extracorporeal membrane oxygenation (ECMO) redeployments are frequently discussed in everyday clinical care. We aim to investigate predictors of mortality in those patients. Clinical data..
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Jan 1, 1970
Definitions of adverse events…
Abstract Extracorporeal membrane oxygenation (ECMO) is a high-risk and low-volume life support with increasing clinical study. However, heterogenous outcome definitions impede data assimilation into evidence to guide practice. The Academic..
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Jan 1, 1970
Extracorporeal cardiopulmonary resuscitation for…
Abstract Aims Current data are insufficient for the leading resuscitation societies to advise on the use of extracorporeal cardiopulmonary resuscitation (ECPR) for pediatric out-of-hospital cardiac arrest (OHCA). The aim of..
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Jan 1, 1970
Aortic Dissection in a…
Abstract Extracorporeal life support (ECLS) therapy is increasingly being used to support children with refractory cardiorespiratory failure, but its use is occasionally associated with complications. Neonatal aortic dissection in association..
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Jan 1, 1970
Cerebral autoregulation monitoring using…
Abstract Objective To investigate whether is impaired after neonatal cardiac surgery and whether changes in metrics are associated with different or the incidence of postoperative neurologic events. Methods This is a retrospective observational..
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Jan 1, 1970
Effects of Fibrinogen Concentrate…
Abstract The use of allogeneic blood products to restore hemostasis during pediatric cardiac surgery is associated with major risks. Consequently, there has been a growing interest in new patient blood..
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Jan 1, 1970
International treatment outcomes of…
Abstract Background PPHN is a common cause of neonatal respiratory failure and is still a serious condition and associated with high mortality. Objectives To compare the demographic variables, clinical characteristics,..
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Jan 1, 1970
Prolonged extracorporeal membrane oxygenation…
Abstract Background In this study, we aimed to evaluate the duration of extracorporeal membrane oxygenation (ECMO) and its effect on outcomes. Also, we sought to identify hospital mortality predictors and..
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Jan 1, 1970
Impact of nitric oxide…
Abstract Objective The impact of nitric oxide (NO) administered via cardiopulmonary bypass (CPB) on pediatric heart surgery remains controversial. The objective of this study is to conduct a comprehensive systematic..
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Jan 1, 1970
Extracorporeal Cardiopulmonary Resuscitation Use…
Abstract Objective: Epidemiologic data on extracorporeal cardiopulmonary resuscitation (ECPR) use in children with cardiac disease after in-hospital cardiac arrest (IHCA) are lacking. We aimed to investigate trends in ECPR use..
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Jan 1, 1970
Comparison of red blood…
Abstract Objective To evaluate the association of RBC transfusions with thrombosis in pediatric patients on extracorporeal membrane oxygenation (ECMO) and compare this with the transfusion of other blood products and..
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Jan 1, 1970
The effect of intraoperative…
Abstract Introduction Cerebral oxygen desaturation during pediatric surgery has been associated with adverse perioperative outcomes. The aim of this pilot study was to analyze the frequency and severity of intraoperative..
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Jan 1, 1970
The American Association for…
Abstract Objectives Symptomatic neonates and infants with Ebstein anomaly (EA) require complex management. A group of experts was commissioned by the American Association for Thoracic Surgery to provide a framework..
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Jan 1, 1970
Update on perioperative fluids…
Abstract Adequate fluid management in the in paediatric patients is essential for restoring and maintaining homeostasis and ensuring adequate . A well-designed infusion regimen is crucial for preventing severe complications such as hyponatraemic encephalopathies...
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Jan 1, 1970
Development and Validation of…
Abstract We sought to develop and validate a new risk stratification score for mortality for children supported with a ventricular assist device (VAD). This retrospective, multicenter study used data from..
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Jan 1, 1970
Partial cardiopulmonary bypass through…
Abstract Background A left thoracotomy approach is anatomically appropriate for childhood aortic coarctation; however, the pediatric femoral arteriovenous diameters are too small for cardiopulmonary bypass cannulation. We aimed to determine..
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Jan 1, 1970
Quantifying potential fluid transfused…
Abstract Pressure monitoring on pediatric Extracorporeal Membrane Oxygenation (ECMO) circuits is used to aid in the evaluation of patient hemodynamics and circuit health. Extracorporeal Life Support Organization (ELSO) recommends monitoring..
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Jan 1, 1970
Extubated, Rehabilitation-Focused Extracorporeal Membrane…
Abstract During the coronavirus 2019 (COVID-19) pandemic, children suffered severe lung injury resulting in acute respiratory distress syndrome requiring support with extracorporeal membrane oxygenation (ECMO). In this case series, we..
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Jan 1, 1970
The Role of Imaging…
Abstract OBJECTIVE. Extracorporeal membrane oxygenation (ECMO) is increasingly widely used in pediatric respiratory failure. Despite playing a key part in patient management during ECMO, the role of radiology is not widely..
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Jan 1, 1970
Pediatric Hematology and Oncology…
Abstract Objective: To describe characteristics associated with survival for pediatric patients with an oncologic diagnosis or hematopoietic cell transplant (HCT) supported with extracorporeal membrane oxygenation (ECMO). Design: Multicenter, retrospective study...
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Jan 1, 1970
Normoxic Management during Cardiopulmonary…
Abstract Optimal oxygen management during pediatric cardiopulmonary bypass (CPB) is unknown. We previously demonstrated an increase in cortical mitochondrial reactive oxygen species and decreased mitochondrial function after CPB using hyperoxic..
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Jan 1, 1970
High reliability pediatric heart…
Abstract Purpose of review The purpose of this review is to examine high reliability through the lens of a contemporary pediatric heart center, noting that continuous improvement, rather than perfection,..
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Jan 1, 1970
The Pediatric Extracorporeal Membrane…
Abstract OBJECTIVES: To present recommendations and consensus statements with supporting literature for the clinical management of neonates and children supported with extracorporeal membrane oxygenation (ECMO) from the Pediatric ECMO Anticoagulation..
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Jan 1, 1970
Perfusion techniques for an…
Abstract Early cardiac surgery in neonates and infants with congenital heart disease has been performed since the middle to late years of the twentieth century. To date, there are very..
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Jan 1, 1970
Management of Left Ventricular…
Abstract Postoperative survival for complete atrioventricular septal defect (cAVSD) is excellent. Common complications of surgery include valvular stenosis/regurgitation, left ventricular outflow tract obstruction, arrythmias, and residual defects. We report a..
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Jan 1, 1970
Outcomes of heart transplants…
Abstract OBJECTIVES End-stage congenital heart disease (CHD) in children with heterotaxy syndrome might necessitate a heart transplant (HTx). An HTx in heterotaxy patients can be associated with several technical (e.g...
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Jan 1, 1970
A Review of Pediatric…
Abstract Though pediatric cardiomyopathy is rare in children, there is significant associated morbidity and mortality. Etiology varies from inborn errors of metabolism to familial genetic mutations and myocyte injury. Major..
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Jan 1, 1970
Bicuspid aortic valve: The…
Abstract Bicuspid aortic valve (BAV) is the most frequent congenital heart disease, with an incidence of approximately 1%. It can be silent and associated with normal valve function. However, a..
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Jan 1, 1970
Factors Affecting the Discrepancy…
Abstract In unfractionated heparin (UFH) monitoring during extracorporeal circulation, the traditional measures of activated clotting time (ACT) or activated partial thromboplastin time (APTT) may diverge, confounding anticoagulant adjustments. We aimed..
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Jan 1, 1970
The Use of Impella…
Abstract This case report explores the successful use of the Impella 5.5 (Abiomed Inc., Danvers, MA) device in a 22 kg, 0.89 body surface area (BSA) pediatric patient with longstanding dilated..
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Jan 1, 1970
New Right Ventricular Dysfunction…
Abstract The development of new right ventricular (RV) dysfunction after cannulation to venovenous (VV) extracorporeal membrane oxygenation (ECMO) and its association with worse outcomes is increasingly recognized in adult patients,..
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Jan 1, 1970
Probiotics may alleviate intestinal…
Abstract OBJECTIVES Intestinal ischaemia–reperfusion injury induced by cardiopulmonary bypass causes intestinal epithelial barrier dysfunction, leading to dysbiosis and bacterial translocation. We conducted a randomized prospective study with 2 objectives: (i)..
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Jan 1, 1970
CytoSorbents STAR Registry Data…
PRINCETON, N.J., June 04, 2024 (GLOBE NEWSWIRE) -- CytoSorbents Corporation (NASDAQ: CTSO), a leader in the treatment of life-threatening conditions in the intensive care unit and cardiac surgery using blood purification via..
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Jan 1, 1970
Cardiac Surgery-Associated Acute Kidney…
Abstract OBJECTIVES: Cardiac surgery-associated acute kidney injury (CS-AKI) is associated with adverse outcomes. Single-center studies suggest that the prevalence of CS-AKI is high after the Norwood procedure, or stage 1..
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Jan 1, 1970
Extracorporeal Membrane Oxygenation for…
Abstract Refractory septic shock is associated with a high risk of death. Circulatory support in the form of veno-arterial extracorporeal membrane oxygenation (VA ECMO) may function as a bridge to..
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Jan 1, 1970
A novel approach to…
Abstract Introduction Retrograde Autologous Priming (RAP) of cardiopulmonary bypass (CPB) circuits is an effective way to reduce prime volume, commonly through the transfer of prime into separate reservoirs or circuit..
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Jan 1, 1970
The safe addition of…
Abstract Background: Nitric Oxide (NO) is a naturally occurring modulator of inflammation found in the human body. Several studies in the pediatric cardiothoracic surgery literature have demonstrated some beneficial clinical effects..
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Jan 1, 1970
What the pediatric nurse…
Abstract Background: Cardiogenic shock in children still carries a high mortality risk despite advances in medical therapy. The use of temporary mechanical circulatory supports is an accepted strategy to bridge patients..
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Jan 1, 1970
The approach to extracorporeal…
Abstract Extracorporeal Cardiopulmonary Resuscitation (ECPR) has potential benefits compared to conventional Cardiopulmonary Resuscitation (CCPR) in children. Although no randomised trials for paediatric ECPR have been conducted, there is extensive literature..
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Jan 1, 1970
Epidemiology of anticoagulation for…
Abstract Introduction Due to the risk of thrombosis, nearly all children supported by extracorporeal membrane oxygenation (ECMO) receive systemic anticoagulation. While heparin has traditionally been used, there are reports of..
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Jan 1, 1970
Primary neonatal and pediatric…
Abstract Introduction: The organization of primary Extracorporeal membrane oxygenation (ECMO) transport is highly variable. Methods: To present the experience of the first mobile pediatric ECMO program in Spain, we designed a prospective..
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Jan 1, 1970
Massive Transfusion in Pediatric…
Abstract Few data describe pediatric patients who receive massive transfusion for life-threatening hemorrhage (LTH) while on extracorporeal membrane oxygenation (ECMO). We present a retrospective secondary analysis of a multicenter prospective..
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Jan 1, 1970
Effective Apixaban removal using…
Abstract Background The management of hemostasis in patients medicated with apixaban (Eliquis) undergoing emergency cardiac surgery is exceedingly difficult. The body’s natural elimination pathways for apixaban prove ineffective in emergency..
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Jan 1, 1970
Risk factors and incidence…
Abstract Delirium, a form of acute cerebral dysfunction, is a common complication of postoperative cardiac surgery in children. It is strongly associated with adverse outcomes, including prolonged hospitalization, increased mortality,..
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Jan 1, 1970
Brain development in newborns…
Abstract Background Extracorporeal membrane oxygenation (ECMO) not only significantly improves survival rates in severely ill neonates but also is associated with long-term neurodevelopmental issues. To systematically review the available literature..
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Jan 1, 1970
Clinical Outcomes, Blood Utilization,…
Abstract BACKGROUND: Pediatric patients requesting bloodless care represent a challenging clinical situation, as parents cannot legally refuse lifesaving or optimal interventions for their children. Here, we report clinical outcomes for..
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Jan 1, 1970
Electroencephalography as a tool…
Abstract Objectives Recent research suggests that increased cerebral oxygen use during surgical intervention for neonates with congenital heart disease may play a role in the development of postoperative white matter..
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Jan 1, 1970
Randomized controlled trial of…
Abstract Background Children undergoing cardiac surgery are at risk for acute kidney injury (AKI) and cardiac dysfunction. Opportunity exists in protecting end organ function with remote ischemic preconditioning. We hypothesize..
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Jan 1, 1970
Pao2 and Mortality in…
Abstract Objectives: Extracorporeal life support can lead to rapid reversal of hypoxemia but the benefits and harms of different oxygenation targets in severely ill patients are unclear. Our primary objective..
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Jan 1, 1970
Epidemiologic trends, risk factors…
Abstract Background During the peak of the COVID pandemic, there was a high degree of awareness around myocarditis as a potential manifestation. However, it is not very clear if hospitalizations..
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Jan 1, 1970
Extracorporeal Membrane Oxygenation After…
Abstract There are minimal data describing use of extracorporeal membrane oxygenation (ECMO) in pediatric patient after a liver transplantation (LT). This study aimed at describing ECMO run in this specific..
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Jan 1, 1970
Preclinical Proof-of-Concept of a…
Abstract Purpose For pediatric patients, extracorporeal membrane oxygenation (ECMO) remains the predominant mechanical circulatory support (MCS) modality for heart failure (HF) although survival to discharge rates remain between 50 and..
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Jan 1, 1970
Clinical Effects of Nitric…
Abstract Nitric oxide (NO) can be safely delivered through the sweep gas to the oxygenator of an extracorporeal membrane oxygenation (ECMO) circuit. It has theoretical benefits such as preventing platelet..
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Jan 1, 1970
Cerebral microhemorrhages in children…
Abstract Background Infants with complex congenital heart disease (CHD) require life-saving corrective/palliative heart surgery in the first weeks of life. These infants are at risk for brain injury and poor neurodevelopmental..
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Jan 1, 1970
Cytosorb Guide – English/Spanish
CytoSorb® Therapy extracorporeal blood purification is used: • in conditions where excessive levels of cytokines, bilirubin and/or myoglobin exist. • intraoperatively during cardio-pulmonary bypass (CPB) surgery for the removal of..
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Jan 1, 1970
Impact of pre-bypass ultrafiltration…
Abstract Background: A standard blood prime for cardiopulmonary bypass (CPB) in congenital cardiac surgery may possess non-physiologic values for electrolytes, glucose, and lactate. Pre-bypass Ultrafiltration (PBUF) can make these values..
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Jan 1, 1970
Statistical analysis plan for…
Abstract Background: The during (CPB) to improve Recovery in Infants with (NITRIC) trial, a 1320-patient, multicentre, , is aiming to improve survival free of ventilation after CPB by using nitric oxide delivered into the of the..
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Jan 1, 1970
First report of successful…
Abstract is a refractory disease caused by microbial invasion of the bone, leading to destruction of the . It is more common in children. Osteomyelitis requires long at high cost and is..
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Jan 1, 1970
Effect of Red Blood…
Abstract BACKGROUND: Red blood cell (RBC) transfusions are used frequently in pediatric patients admitted to the intensive care unit (ICU) after cardiac surgery. To improve data-driven transfusion decision-making in the..
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Jan 1, 1970
Nonresuscitation Fluid Accumulation and…
Abstract OBJECTIVES: Postoperative patients after congenital cardiac surgery are at high risk of fluid overload (FO), which is known to be associated with poor outcomes. “Fluid creep,” or nonresuscitation IV..
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Jan 1, 1970
Performance Evaluation of Geometrically…
Abstract Objective: To define a reference chart comparing pressure drop vs. flow generated by a set of arterial cannulae currently utilized in cardiopulmonary bypass conditions in pediatric surgery. Methods: Cannulae from two..
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Jan 1, 1970
Preoperative Sildenafil in Pediatric…
Abstract Background. Pulmonary hypertension (PH) is a common complication of congenital heart disease (CHD). With early surgical intervention, outcomes have improved over the last two decades. Persistent PH, however, may..
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Jan 1, 1970
Predicting pediatric cardiac surgery-associated…
Abstract Background Prediction of cardiac surgery-associated acute kidney injury (CS-AKI) in pediatric patients is crucial to improve outcomes and guide clinical decision-making. This study aimed to develop a supervised machine..
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Jan 1, 1970
Use of point‑of‑care ultrasound…
Abstract Extracorporeal membrane oxygenation (ECMO) is an invasive life support technique that requires a blood pump, an artificial membrane lung, and vascular cannulae to drain de-oxygenated blood, remove carbon dioxide,..
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Jan 1, 1970
Effect of red blood…
Abstract Objective This study aimed to determine whether or not transfusion of fresh red blood cells (RBCs) reduced the incidence of new or progressive multiple organ dysfunction syndrome compared with..
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Jan 1, 1970
Recommendations for centers performing…
Abstract Care and outcomes for the more than 40,000 patients undergoing pediatric and congenital heart surgery in the United States annually are known to vary widely. While consensus recommendations have..
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Jan 1, 1970
Dose Effect of Mesenchymal…
Abstract Background Neurologic impairments are a significant concern for survivors after cardiac surgery with (CPB). We have previously shown that mesenchymal stromal cell (MSC) delivery through CPB has the potential to mitigate the effects..
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Jan 1, 1970
Factor XI Inhibition With…
Abstract Extracorporeal membrane oxygenation (ECMO) supplies circulatory support and gas exchange to critically ill patients. Despite the use of systemic anticoagulation, blood exposure to ECMO surfaces causes thromboembolism complications. Inhibition..
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Jan 1, 1970
Carboxyhemoglobin and Methemoglobin Levels…
Abstract Hemolysis is a complication of cardiopulmonary bypass (CPB). Carboxyhemoglobin (COHb) and methemoglobin (MetHb) were suggested as potential hemolysis biomarkers. This retrospective study was based on a prospective registry aimed..
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Jan 1, 1970
Perioperative prophylactic corticosteroids for…
Abstract Objective Perioperative corticosteroids have been used for cardiac surgery for decades, but the underlying evidence is conflicting. We aimed to investigate the efficacy and safety of perioperative prophylactic corticosteroids in heart..
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Jan 1, 1970
Depth of anesthesia, temperature,…
Abstract Background After pediatric cardiosurgical interventions, postoperative delirium can occur, which can be associated with undesirable consequences during and after the hospital stay. It is therefore important to avoid any..
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Jan 1, 1970
Balloon atrial septostomy versus…
Abstract Introduction In children with myocarditis or dilated cardiomyopathy (DCM) on extracorporeal membrane oxygenation (ECMO) for cardiogenic shock, it is often necessary to decompress the left heart to minimize distension..
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Jan 1, 1970
Contemporary Outcomes of Children…
Abstract Despite extracorporeal membrane oxygenation (ECMO) utilization in nearly 20% of cases, there are limited data in children with acute fulminant myocarditis (AFM) requiring ECMO. Herein we identify risk factors..
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Jan 1, 1970
Adjunctive Hemoadsorption Therapy with…
Abstract A dysregulated host response is a common feature in critically ill patients due to both infectious and non-infectious origins that can lead to life-threatening organ dysfunction, which is still..
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Jan 1, 1970
CytoSorb® in Combination with…
This case reports on an 53-year-old female patient who was admitted to the hospital with an 8 day history of fever and chills, loose stools, vomiting, severe weakness, and reduced..
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Jan 1, 1970
Analysis of P(v-a)CO2/C(a-v)O2 Ratio…
Abstract Background: The so-called Low Cardiac Output Syndrome (LCOS) is one of the most common complications in pediatric patients with congenital heart disease undergoing corrective surgery. LCOS requires high..
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Jan 1, 1970
The choice of perioperative…
Abstract BACKGROUND: Vaso-inotropic agents are frequently used to prevent and/or treat low cardiac output syndrome in infants undergoing surgery for congenital heart disease. Due to the lack of comparative studies,..
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Jan 1, 1970
Circuit change in neonatal…
Abstract Introduction Extracorporeal membrane oxygenation (ECMO) circuits may be changed during the run for multiple reasons; however, these circuit changes may be associated with adverse events. Predictors for undergoing a..
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Jan 1, 1970
Encouraging results of blood…
Abstract Objective To report early outcomes of blood conservation in neonatal open-heart surgery. Methods Ninety-nine patients undergoing neonatal open-heart surgery during the implementation of a blood conservation program between May..
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Jan 1, 1970
The beneficial use of…
Abstract Purpose Investigate inhaled nitric oxide’s influence on mortality rates, mechanical ventilation and cardiopulmonary bypass duration, and length of stay in the intensive care unit and hospital when administered during..
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Jan 1, 1970
Central Extracorporeal Membrane Oxygenation…
Abstract Refractory vasodilatory shock (RVS) following massive calcium channel blocker (CCB) overdose remains a challenging clinical entity. Peripheral venoarterial extracorporeal membrane oxygenation (ECMO) has proven useful in several cases of..
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Jan 1, 1970
Changes in Cerebral Regional…
Abstract Near-infrared spectroscopy is routinely used in the monitoring of cerebral regional oxygen saturation (crSO2) in neonates following congenital heart surgery. Decreased postoperative crSO2 variability in these patients is associated with..
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Jan 1, 1970
2023 International Consensus on…
Abstract The International Liaison Committee on Resuscitation engages in a continuous review of new, peer-reviewed, published cardiopulmonary resuscitation and first aid science. Draft Consensus on Science With Treatment Recommendations are..
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Jan 1, 1970
Pediatric Highlights From the…
Abstract The Extracorporeal Life Support Organization (ELSO) registry which collects data from hundreds of participating centers supports research in ECMO to help improve patient outcomes. The ELSO Scientific Oversight Committee,..
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Jan 1, 1970
Influence of Fibrinogen Concentrate…
Abstract BACKGROUND: Bleeding is a serious complication of cardiopulmonary bypass (CPB) in neonates. Blood product transfusions are often needed to adequately restore hemostasis, but are associated with significant risks. Thus,..
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Jan 1, 1970
Improving Outcomes for Infants…
Abstract Congenital heart disease (CHD) represents one of the most common congenital malformations, affecting greater than 40,000 births annually in the United States, many of which require surgery during the..
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Jan 1, 1970
Peripheral Veno-Arterial-Extracorporeal Membrane Oxygenation…
Abstract Background Extracorporeal membrane oxygenation (ECMO) is utilized as a rescue therapy in the management of pediatric patients with refractory septic shock. Multiple studies support the use of a central..
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Jan 1, 1970
Early Changes in Arterial…
Abstract Objective: Neurologic complications in pediatric patients supported by extracorporeal membrane oxygenation (ECMO) are common and lead to morbidity and mortality; however, few modifiable factors are known. Design: Retrospective study..
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Jan 1, 1970
Indexed oxygen delivery during…
Abstract Background: Acute kidney injury after pediatric cardiac surgery is a common complication with few established modifiable risk factors. We sought to characterize whether indexed oxygen delivery during cardiopulmonary bypass..
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Jan 1, 1970
Custodiol versus blood cardioplegia…
Abstract Background Blood-based cardioplegia is the standard myocardial protection strategy in pediatric cardiac surgery. Custadiol (histidine-tryptophan-ketoglutarate), an alternative, may have some advantages but is potentially less effective at myocardial protection...
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Jan 1, 1970
Plasma-Free Strategy for Cardiac…
Abstract Background: Infants < 10 kg undergoing cardiac surgery with cardiopulmonary bypass (CPB) may receive either fresh frozen plasma (FFP) or other solutions in the CPB priming volume. The existing..
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Jan 1, 1970
Efficacy and safety of…
Abstract Background and aims: Cardiopulmonary bypass (CPB) utilized for cardiac surgeries has been associated with significant mortality and adverse outcomes. The benefits of incorporating nitric oxide (NO) into the CPB..
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Jan 1, 1970
Association Between Thrombin–Antithrombin Complex…
Abstract Vascular endothelial damage may activate hypercoagulation and contribute to the development of acute kidney injury (AKI). This study aimed to investigate whether early alteration in coagulation was associated with..
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Jan 1, 1970
ECMO for Premature Neonates-…
Abstract Despite ECMO being a well-accepted and established life-saving support for newborns, prematurity (<34 weeks of gestation) and low birth weight <2.0 kg are still considered relative contraindications due to..
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Jan 1, 1970
Challenges of Nutrition Support…
Abstract Nutrition support in critically ill infants and children remains an integral part of providing optimal care for these patients. The pediatric patient requiring extracorporeal membrane oxygenation therapy faces specific..
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Jan 1, 1970
Veno-venous extracorporeal membrane oxygenation,…
This case reports on a 41-years old male with no significant medical history who was admitted to the emergency room following 25% total body surface area (TBSA) deep partial thickness..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 29-year-old male, who was transferred from a peripheral hospital with a diagnosis of COVID-19-associated lower respiratory tract infection, septic shock, and multiple organ dysfunction syndrome..
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Jan 1, 1970
Ultrasonic Prediction of Weaning…
Abstract Background and Aim: To assess the utility of ultrasonic markers like B-line score (LUS), diaphragm thickness (DT), thickening fraction (DTF), and excursion (DE) as predictors of weaning outcomes in..
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Jan 1, 1970
Activated Prothrombin Complex Concentrate…
Abstract Background Pediatric cardiac surgery is associated with abnormal coagulation, bleeding, and nearly ubiquitous transfusions. With the popularization of patient blood management, attempts are being made to decrease liberal transfusions..
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Jan 1, 1970
Low-Dose Vasopressin and Renal…
Abstract Background: Congenital heart surgeries are associated with post-bypass renal and cardiac dysfunctions. The use of low-dose vasopressin has been found to be beneficial in adult cardiac surgeries. Objective: To..
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Jan 1, 1970
Extracorporeal Blood Purification with…
Abstract Introduction: Critically ill patients with inflammatory dysregulation and organ disfunction may benefit from blood purification, although the use of this technique has not been described in large case series. We..
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Jan 1, 1970
CytoSorb with Ex Vivo…
Abstract PRINCETON, N.J., Sept. 11, 2023 (GLOBE NEWSWIRE) -- (NASDAQ: CTSO), a leader in the treatment of life-threatening conditions in intensive care and cardiac surgery using blood purification via its..
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Jan 1, 1970
Antithrombin III supplementation during…
Abstract Background Bleeding and thrombosis are common extracorporeal membrane oxygenation (ECMO) complications associated with increased mortality. Heparin is the most commonly used ECMO anticoagulant, employed in 94% of cases. Reduced..
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Jan 1, 1970
Children who suffer cardiac…
Abstract Children who experience cardiac arrest are one and a half times more likely to survive at a hospital capable of providing the life support system called ECMO, research suggests...
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Jan 1, 1970
Efficacy of CytoSorb®: a…
Abstract Introduction Cytokine adsorption using the CytoSorb® adsorber has been proposed in various clinical settings including sepsis, ARDS, hyperinflammatory syndromes, cardiac surgery or recovery after cardiac arrest. The aim of..
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Jan 1, 1970
Development and Validation of…
Abstract BACKGROUND: Heparin resistance (HR) is a common finding in pediatric cardiac surgery and generally refers to decreased sensitivity to heparin. Antithrombin (AT) deficiency is considered the primary mechanism of..
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Jan 1, 1970
Prevalence and Clinical Implications…
Abstract Importance Phthalate chemicals are used to manufacture disposable plastic medical products, including blood storage bags and components of cardiopulmonary bypass (CPB) circuits. During cardiac surgery, patients can be inadvertently exposed..
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Jan 1, 1970
Benefit From a Humanitarian…
Abstract Background: The charity organization Kinderherzen retten e.V. (KHR) enables humanitarian congenital heart surgery for pediatric patients from low- and middle-income countries at the University Heart Center Freiburg, Germany. The aim of this..
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Jan 1, 1970
Cardiopulmonary bypass in neonates…
Abstract Cardiopulmonary bypass is an integral and indispensable part of surgical repair of congenital heart defects. While the complications and morbidity secondary to the use of cardiopulmonary bypass has decreased..
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Jan 1, 1970
Strategies to mitigate inflammation…
This case reports on a six month old male patient (weight 6 kg), who presented with agonal respiration and history of acute febrile illness. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2023/08/CoM_08_2023_E_web_compressed-1.pdf" title="CoM_08_2023_E_web_compressed"]
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Jan 1, 1970
Effective Treatment of Acute…
Abstract BACKGROUND Tricyclic antidepressant (TCA) drugs are a common cause of fatal poisoning because of their cardiotoxic and arrhythmogenic effects. Classic supportive management includes sodium bicarbonate, gastrointestinal chelating agents, and..
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Jan 1, 1970
Successful use of extracorporeal…
This case reports on a 17-year-old female patient who was admitted to a regional hospital for mixed intoxication with a presumed intake of 24 g of venlafaxine (both immediate and..
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Jan 1, 1970
Venovenous Extracorporeal Membrane Oxygenation…
Abstract Objective: To determine the association of venovenous extracorporeal membrane oxygenation (VV-ECMO) initiation with changes in vasoactive-inotropic scores (VISs) in children with pediatric acute respiratory distress syndrome (PARDS) and cardiovascular instability. Design: Retrospective cohort..
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Jan 1, 1970
Impact of the Pediatric…
Abstract Background: We assessed the impact of the liberalized ABO pediatric policy change on candidate characteristics and outcomes for children undergoing heart transplant (HT). Methods and results: Children <2 years undergoing HT..
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Jan 1, 1970
Outcomes after neonatal cardiac…
Abstract Objectives Prematurity is a risk factor for in-hospital mortality after cardiac surgery. The structure of models designed to deliver optimal care to neonates including those born preterm with critical is unknown...
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Jan 1, 1970
Exogenous nitric oxide delivery…
Abstract Objective Several human studies have associated nitric oxide administration via the cardiopulmonary bypass circuit with decreased incidence of cardiopulmonary bypass–associated acute kidney injury, but histopathologic and serologic evidence of..
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Jan 1, 1970
Modified Ultrafiltration Should Not…
Abstract Pediatric Literature As the practice of ultrafiltration arose from pediatric cardiac surgery, much of the evidence to support MUF is from low-powered pediatric studies. Some early, single-center literature, as..
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Jan 1, 1970
Modified Ultrafiltration Is Beneficial…
Abstract Hemodilution and Volume Overload The use of CPB necessitates priming of the CPB circuit, which is typically accomplished using 1-to-2 liters of a crystalloid solution. In addition, 1-to-3 liters..
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Jan 1, 1970
The Nikaidoh Operation: An…
The patient is a two-and-a-half-year-old child with d-TGA/VSD/PS who underwent aortic translocation. The patient’s anatomy was typical of d-transposition with VSD and PS. Both coronaries were favorable in that they..
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Jan 1, 1970
It All Circles Back…
Abstract Clinicians caring for children with cardiopulmonary failure using extracorporeal membrane oxygenation (ECMO) are refining bedside clinical practices by focusing on minimizing morbidity associated with neurologic complications. Neurologic complications are the main drivers of survival..
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Jan 1, 1970
Computed Tomography Is Predictive…
Abstract Extracorporeal membrane oxygenation (ECMO) augments cardiopulmonary function in critically ill children through use of large vessel cannulation and an external pump-oxygenator system. While advances in ECMO have allowed more children..
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Jan 1, 1970
Cytosorb Adsorption During Emergency…
Abstract Background The purpose of this study was to analyze the results of Cytosorb (CytoSorbents, Monmouth Junction, NJ) adsorption during emergency open heart operations in patients at high risk of..
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Jan 1, 1970
Reducir el riesgo de…
Terapia CytoSorb en Cirugía Cardíaca de urgencia y emergencia. CytoSorb reduce las complicaciones de hemorragia en pacientes de emergencia al eliminar de modo efectivo el ticagrelor y el rivaroxaban de..
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Jan 1, 1970
Analysis of perioperative corticosteroid…
Abstract The advantages and disadvantages of using corticosteroids in children undergoing cardiac surgery is still contentious. To examine how perioperative corticosteroids affect postoperative mortality and clinical outcomes in pediatric cardiac..
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Jan 1, 1970
Cardiac arrest and cardiopulmonary…
Abstract Children with cardiac disease are at a higher risk of cardiac arrest as compared to healthy children. Delivering adequate cardiopulmonary resuscitation (CPR) can be challenging due to anatomic characteristics,..
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Jan 1, 1970
Minimized Hemodiafiltration for Extracorporeal…
Abstract Background Fluid overload is a serious complication in the treatment of infants with extracorporeal membrane oxygenation (ECMO). Volume overload leads to prolonged ECMO therapy if left untreated. The renal..
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Jan 1, 1970
Extracorporeal hemoadsorption in critically…
Abstract Objectives: The CytoSorb therapy in COVID-19 (CTC) registry evaluated the clinical performance and treatment parameters of extracorporeal hemoadsorption integrated with veno-venous extracorporeal membrane oxygenation (VV ECMO) in critically ill COVID-19..
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Jan 1, 1970
Longitudinal assessment of cerebral…
Abstract Longitudinal assessment of brain perfusion is a critical parameter for neurodevelopmental outcome of neonates undergoing cardiopulmonary bypass procedure. In this study, we aim to measure the variations of cerebral..
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Jan 1, 1970
Preceding Clinical Events in…
Abstract Objective: Blood stream infections (BSIs) are well described in pediatric cardiac intensive care units (PCICU). We noted that postoperative high-risk patients may develop BSI after a preceding clinical event (PCE)...
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Jan 1, 1970
Hospital ECMO capability is…
Abstract Aim Extracorporeal membrane oxygenation (ECMO) provides temporary support in severe cardiac or respiratory failure and can be deployed in children who suffer cardiac arrest. However, it is unknown if..
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Jan 1, 1970
Modifications to therapeutic plasma…
Abstract Background Cardiac transplants increasingly occur following placement of ventricular assist devices (VADs). A strong association exists between human leukocyte antigen (HLA) sensitization and VAD placement; however, desensitization protocols that..
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Jan 1, 1970
Regional Cerebral Oxygen Saturation…
Abstract Regional cerebral oxygen saturation (ScO2) determined by near-infrared spectroscopy, monitoring both arterial and venous blood oxygenation of the brain, could reflect the balance between oxygen delivery and consumption. The..
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Jan 1, 1970
Assessing Risk Factors for…
Abstract Background Prolonged post-surgery intensive care unit (ICU) stay for congenital heart disease (CHD) has been explored in the pediatric population. However, there is limited data for adult CHD (ACHD),..
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Jan 1, 1970
Bacteria in Extracorporeal Membrane…
Abstract A neonate with pulmonary hypertension was supported with extracorporeal membrane oxygenation (ECMO). During ECMO support, the patient developed Enterococcus faecalis bacteremia, treated with targeted antibiotics. Despite the maximum dose of antibiotics, routine blood..
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Jan 1, 1970
A report of the…
Abstract Cardiac donation after circulatory death (DCD) with ex-vivo perfusion (EVP) has the potential to greatly increase the donor pool, a benefit that can extend to selected pediatric patients. We..
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Jan 1, 1970
Absolute Versus Relative Near-Infrared…
Abstract OBJECTIVES: Near-infrared spectroscopy (NIRS) has been increasingly accepted as a noninvasive marker of regional tissue oxygenation despite concerns of imprecision and wide limits of agreement (LOA) with invasive oximetry. New generation absolute..
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Jan 1, 1970
Use of CytoSorb for…
This case reports on a 43-year-old pregnant woman, who was hospitalized for an anticipated complicated delivery. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/05/CoW_19_2021_E_web_compressed.pdf"]
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Jan 1, 1970
Refraining from Packed Red…
Abstract Congenital heart defect (CHD) surgeries are performed with cardiopulmonary bypass (CPB) and are complicated by several factors that affect the child’s brain. However, to date, the number of studies..
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Jan 1, 1970
Centrifugal or Roller Blood…
Abstract Objectives: To investigate outcomes associated with conventional roller or centrifugal pumps during neonatal venovenous extracorporeal membrane oxygenation (ECMO). Our primary hypothesis is that in comparison with conventional roller-pump support, centrifugal pump use is..
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Jan 1, 1970
A Surgeon’s Perspective on…
Abstract Blood conservation practice in pediatric cardiac surgery has not been consistently adopted as quality improvement in many centers despite known risks associated with allogeneic blood products, shortage of donors,..
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Jan 1, 1970
Cost-effectiveness of bivalirudin in…
Abstract Background Despite recent data suggesting improved outcomes with bivalirudin vs heparin in pediatric Ventricular assist devices (VAD), higher costs remain a barrier. This study quantified trends in bivalirudin use..
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Jan 1, 1970
Does a balanced colloid…
Abstract BACKGROUND Unbalanced fluid solutions cause metabolic acidosis and could be associated with impaired coagulation and increased blood loss. OBJECTIVE To investigate whether the use of a balanced colloid compared..
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Jan 1, 1970
Early rehabilitation and mobilisation…
Abstract Despite increasing early rehabilitation and mobilisation (ERM) in paediatric intensive care, current evidence for ERM of neonatal and paediatric patients receiving extracorporeal membrane oxygenation (ECMO) is limited. The proposed..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 34-year-old male patient with a history of heavy alcohol intake (1 bottle of wine per day for the past 15 years) but no other comorbidities,..
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Jan 1, 1970
Extracorporeal Membrane Oxygenation Characteristics…
Abstract Objectives: Extracorporeal membrane oxygenation (ECMO) has been used successfully to support adults with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related cardiac or respiratory failure refractory to conventional therapies. Comprehensive..
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Jan 1, 1970
Antithrombin Replacement and Extracorporeal…
Abstract The use of extracorporeal membrane oxygenation (ECMO) circuit obligates the administration of systemic anticoagulation to avoid patient and circuit thrombosis. Identifying an optimal approach for achievement of target pharmacologic..
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Jan 1, 1970
Clinical Predictive Tool for…
Abstract Fluid overload is common among pediatric cardiac patients receiving extracorporeal membrane oxygenation (ECMO) and is often treated with in-line ultrafiltration (UF) or continuous renal replacement therapy (CRRT). We assessed whether..
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Jan 1, 1970
ECMO adverse events for…
Presenters: Peta Alexander (Boston Children's Hospital, Boston/USA) Ryan Barbaro (Motts Children's Hospital, Ann Arbor/USA)Moderators: Matteo di Nardo (Rome/Italy) Alain Combes (Paris/France)
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Jan 1, 1970
Use of Image Guidance…
Abstract This study evaluated practices for image guidance during placement of bicaval dual-lumen (BCDL) venovenous extracorporeal membrane oxygenation (VV-ECMO) cannulas in pediatric and adolescent patients and elucidates reasoning behind surgeon..
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Jan 1, 1970
Discontinuation of ECMO, a…
Abstract Extracorporeal membrane oxygenation (ECMO) has strikingly progressed over the last 20 years in the management of adult and pediatric severe respiratory and cardiac dysfunctions refractory to conventional management. In this..
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Jan 1, 1970
Elective and non-elective endomyocardial…
Abstract Background Endomyocardial biopsies are standard of care for transplant surveillance, however the procedural risks are not well established, especially in children. The purpose of the study was therefore to..
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Jan 1, 1970
Assessment of the factors…
Abstract Background: This study aims to evaluate the early extubation rate and the factors affecting early extubation in pediatric patients undergoing cardiac surgery. Methods: Between August 1st, 2020 and December 1st, 2021,..
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Jan 1, 1970
Incidence of Acute Neurological…
Abstract Background: The incidence of new acute neurological injury occurring in neonates and infants during cardiac surgery utilizing cardiopulmonary bypass is reportedly 3% to 5%. In 2013, we adopted a high..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 56-year-old female patient who was admitted to hospital by ambulance with fever (up to 42°C) that had been persisting for 4 days, lower abdominal pain..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 60-year-old male patient who presented to hospital for elective aortocoronary bypass surgery. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2023/03/CoM_02_2023_E_web_compressed.pdf"]
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Jan 1, 1970
Effect of Ventilation Strategy…
Abstract Objectives To compare the effects of 3 ventilation strategies during cardiopulmonary bypass (CPB) on arterial oxygenation and postoperative pulmonary complications (PPCs). Design A prospective, randomized, controlled study. Setting A..
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Jan 1, 1970
Exploring Noncardiac Surgical Needs…
Abstract Objectives As life expectancy for patients born with congenital heart disease (CHD) continues to rise, these patients will present increasingly for noncardiac surgery during childhood and adolescence. This study..
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Jan 1, 1970
PROTOCOLO NACIONAL DE TRASPLANTE…
Abstract La práctica del trasplante AB0 incompatible (AB0i) surgió en el Hospital Sick Children de Toronto (Canadá) bajo el liderazgo de la Doctora Lori J. West, cardióloga e inmunóloga pediátrica..
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Jan 1, 1970
Warm versus cold-blood cardioplegia…
Abstract Objectives Intermittent cold blood cardioplegia is commonly used in children whereas intermittent warm blood cardioplegia is widely used in adults. We aimed to compare clinical and biochemical outcomes with..
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Jan 1, 1970
Intraoperative Technical Performance Score…
Abstract Background The utility of the intraoperative technical performance score (IO-TPS) in predicting outcomes after congenital cardiac surgery remains unknown. Methods Data from patients undergoing surgery for from January 2011 to..
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Jan 1, 1970
Causes of red blood…
Abstract Background Pediatric patients on extracorporeal membrane oxygenation (ECMO) often receive repeated red blood cell (RBC) transfusions. This study aims to quantify and characterize causes of RBC loss on ECMO...
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Jan 1, 1970
Executive Summary of the…
Abstract OBJECTIVES: We sought to update our 2015 work in the Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) guidelines for the diagnosis and management of pediatric acute respiratory distress..
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Jan 1, 1970
Extracorporeal Membrane Oxygenation in…
Abstract OBJECTIVES: To systematically review and assimilate literature on children receiving extracorporeal membrane oxygenation (ECMO) support in pediatric acute respiratory distress syndrome (PARDS) with the goal of developing an update to the..
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Jan 1, 1970
Variation in electroencephalography and…
Abstract Background Seizures, strokes, and intracranial hemorrhage are common and feared complications in children receiving extracorporeal membrane oxygenation (ECMO) support. Researchers and clinicians have proposed and deployed methods for monitoring..
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Jan 1, 1970
The characteristics of blood…
Abstract Purpose Blood transfusion is a common and life-saving procedure in congenital heart surgery (CHS), and it is critical for patients to identify risk factors prior to surgery. Our objective..
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Jan 1, 1970
After the storm: Extracorporeal…
Abstract Ventricular arrhythmias following neurological injury have been attributed to sympathetic surge in subarachnoid hemorrhage and traumatic brain injury. Despite associated risks of bleeding and thrombosis, veno-arterial extracorporeal membrane oxygenation..
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Jan 1, 1970
Predictors of Mediastinal Exploration…
Abstract Cardiac surgical patients requiring extracorporeal membrane oxygenation (ECMO) are at increased risk for hemorrhage due to necessary anticoagulation, in-situ cannulas, and disturbed hemostasis. We performed a retrospective, cross-sectional study..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 20-year-old patient with no relevant medical history, who was admitted to the emergency room with severe polytrauma after hitting a stationary car whilst on his..
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Jan 1, 1970
Fluid Accumulation After Neonatal…
Abstract Background This study was conducted to determine the association between fluid balance metrics and mortality and other postoperative outcomes after neonatal cardiac operation in a contemporary multicenter cohort. Methods..
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Jan 1, 1970
Hemostatic Complications During Neonatal…
Abstract Recently three different neonatal extracorporeal membrane oxygenation (ECMO) circuits have been employed in our clinic. These circuits were compared for clotting and bleeding complications. Initially, we used an ECMO..
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Jan 1, 1970
Extracorporeal Membrane Oxygenation Cannulation…
Abstract OBJECTIVES: Children presenting with acute myocarditis may experience rapid clinical deterioration requiring extracorporeal membrane oxygenation (ECMO); however, our understanding of best practices and timing of ECMO initiation are lacking...
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Jan 1, 1970
Single-Center Experience Using the…
Abstract Objectives: Extracorporeal membrane oxygenation (ECMO) systems have continued to evolve and improve with the development of smaller and portable systems. The Cardiohelp (Maquet Getinge Cardiopulmonary AG, Rastatt, Germany) portable..
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Jan 1, 1970
The Sequential Use of…
This case reports on an a 14-year-boy (43 kg) without any respiratory symptoms, who was admitted to a regional hospital with a fever of one day associated with vomiting and..
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Jan 1, 1970
Use of hemadsorption in…
This case reports on an 18-year-old male without relevant medical history, who presented at the emergency room of a peripheral primary care hospital with nausea and headaches. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/12/CoW_42_2022_E_web_compressed.pdf"]
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Jan 1, 1970
Surgical Experience With Crossed…
Abstract Anomalies of the pulmonary origin of the pulmonary arteries are uncommon; however, the true incidence is unknown and may be underestimated. We sought to review our experience with this..
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Jan 1, 1970
Hemadsorption: A New Therapeutic…
This case reports on an a 67-year-old woman with CHILD-C liver cirrhosis, who was admitted to the tertiary intensive care unit (ICU) after intoxication with bromazepam. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/12/CoW_41_2022_E_web_compressed.pdf"]
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Jan 1, 1970
Why identifying adverse events…
Abstract The emergency department (ED) abounds with hazards that might lead to adverse events (AEs). Clinicians must make frequent, high-consequence decisions with high diagnostic uncertainty as part of ad hoc..
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Jan 1, 1970
Early and long-term results…
Abstract OBJECTIVES In upper-income countries, infants undergo low-risk ventricular septal defect (VSD) repair. Children in low- and middle-income countries frequently present at older ages with elevated pulmonary vascular resistance..
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Jan 1, 1970
Hemoadsorption as part of…
This case reports on a 68-year-old male with known arterial hypertension, who presented at the hospital by ambulance following severe deterioration of his general condition including fever up to 39°C,..
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Jan 1, 1970
Use of CytoSorb for…
This case reports on a 37-year-old male patient who was referred from a peripheral hospital with the diagnosis of Dengue fever and multiple organ failure. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/11/CoW_39_2022_E_web_compressed.pdf"]
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Jan 1, 1970
A prospective randomized study…
Abstract Background: Modified ultrafiltration has been touted as superior to conventional ultrafiltration for attenuating the consequences of hemodilution after cardiac surgery with cardiopulmonary bypass in children. We conducted a prospective randomized..
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Jan 1, 1970
Impact of occurrence of…
Abstract Objective: The impact of cardiac arrest in the donor on long-term outcomes of pediatric heart transplantation has not been studied. Methods: The UNOS database was queried for primary pediatric heart transplantation..
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Jan 1, 1970
A prospective randomized study…
Abstract Conventional ultrafiltration (UF) fails to reverse satisfactorily hemodilution and the rise in total body water (TBW) seen after cardiopulmonary bypass (CPB). We have modified the technique, timing, and placement..
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Jan 1, 1970
Modified ultrafiltration in surgical…
Abstract The surgical correction of congenital heart disease using haemodilution and hypothermia with cardiopulmonary bypass (CPB) may expose patients to tissue ischaemia and initiate a systemic inflammatory response, increasing the..
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Jan 1, 1970
A successful modification of…
Abstract Total body water (TBW) is increased after cardiopulmonary bypass (CPB) resulting in tissue oedema and organ dysfunction. Ultrafiltration has been used to reduce this accumulation of water, although conventional..
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Jan 1, 1970
CytoSorb hemoadsorption for removal…
This case reports on an 81-year-old man who presented to the hospital with methicillin-sensitive Staphylococcus aureus prosthetic aortic valve endocarditis and hemodynamic instability requiring an urgent operation (EuroSCORE II 31.05%)..
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Jan 1, 1970
American Society of ExtraCorporeal…
Abstract The American Society of ExtraCorporeal Technology (AmSECT) has created the following document based on clinical evidence and currently accepted perfusion practices. Perfusionists are the only allied healthcare professionals formally..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 55-year-old man with hepatocellular carcinoma in the context of a hepatitis C virus (HCV)-infection since the year 2000, who was hospitalized and scheduled for an..
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Jan 1, 1970
Associations of cephalad drainage…
Abstract Background Neurologic complications can occur during neonatal Veno-Venous (VV) ECMO. The addition of a cephalad drainage cannula (i.e., VVDL+V) to dual lumen cannulation (i.e., VVDL) has been advocated to..
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Jan 1, 1970
Cor triatriatum sinister: Long-term…
Abstract Background: Cor Triatriatum Sinister (CTS) is a rare congenital anomaly with an estimated incidence of 0.4%, resulting from abnormal left atrial septation. It may present in isolation or in association..
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Jan 1, 1970
Use of CytoSorb in…
This report describes the case of a 73-year-old male patient (known pre-existing conditions: bilateral peripheral vascular disease grade 2b, hypercholesterolemia with long-term simvastatin medication) who was admitted to the Emergency..
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Jan 1, 1970
‘Enhanced Lung Rest’ with…
Abstract PRINCETON, N.J., Nov. 2, 2022 /PRNewswire/ -- CytoSorbents Corporation (NASDAQ: ), a leader in the treatment of life-threatening conditions in the intensive care unit and cardiac surgery using its CytoSorb® blood purification technology,..
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Jan 1, 1970
Retraining an Artificial Intelligence…
Abstract Objectives Identifying patients with low left ventricular ejection fraction (LVEF) and monitoring LVEF responses to treatment are important clinical goals. Can a deep-learning algorithm predict pediatric LVEF within clinically..
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Jan 1, 1970
ESPNIC clinical practice guidelines:…
Abstract Purpose Intravenous maintenance fluid therapy (IV-MFT) prescribing in acute and critically ill children is very variable among pediatric health care professionals. In order to provide up to date IV-MFT..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 12-year-old male patient (weight 55 kg) without relevant medical history, who was admitted to the hospital with a three days history of fever associated with..
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Jan 1, 1970
A New Apheresis Device…
This case reports on an a 74-year-old male patient who was admitted to Artemed Klinikum Munich South, for urgent coronary artery bypass grafting (CABG) for severe three-vessel disease (occluded right..
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Jan 1, 1970
A practical guideline for…
Abstract Transthoracic echocardiography is an essential tool in the diagnosis, assessment, and management of paediatric and adult populations with suspected or confirmed congenital heart disease. Congenital echocardiography is highly operator-dependent,..
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Jan 1, 1970
Use of CytoSorb in…
This report describes the case of a 68-year-old patient (known medical history: untreated chronic obstructive pulmonary disease (COPD), ectopic atrial tachycardia, liver cirrhosis CHILD stage B, no contact with physicians..
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Jan 1, 1970
Use of CytoSorb© Hemoadsorption…
Abstract Acute respiratory distress syndrome (ARDS) is associated with high morbidity and mortality. Adjunct hemoadsorption is increasingly utilized to target underlying hyperinflammation derived from ARDS. This article aims to review..
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Jan 1, 1970
Removal of Apixaban during…
Abstract Background: Patients on direct oral anticoagulants are at high risk of perioperative bleeding complicaapitions. We analyzed the results of intraoperative hemoadsorption (HA) in patients undergoing cardiac surgery who were..
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Jan 1, 1970
Factors associated with red…
Abstract Introduction Red blood cell (RBC) transfusion is often required during cardiac surgery in children. However, RBC is a rare product, and its transfusion is associated with adverse events and..
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Jan 1, 1970
Microplegia in paediatric hearts
Abstract Introduction A basic prerequisite for a good surgical outcome in heart surgery is optimal myocardial protection. However, cardioplegia strategies used in adult cardiac surgery are not directly transferable to..
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Jan 1, 1970
Hemolysis during Pediatric Extracorporeal…
Abstract Objective: To describe factors associated with hemolysis during pediatric extracorporeal membrane oxygenation (ECMO), and the relationships between hemolysis, complications and mortality. Design: Secondary analysis of data collected prospectively by..
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Jan 1, 1970
Transfusion policy in pediatric…
Abstract Objective To evaluate a restrictive transfusion policy of red blood cells (RBC) and platelets in pediatric patients submitted to extracorporeal membrane oxygenation (ECMO). Methods Retrospective descriptive study of pediatric..
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Jan 1, 1970
Bivalirudin vs. heparin in…
Abstract Aims Unfractionated heparin (UFH) has been the primary anticoagulant of choice on extracorporeal membrane oxygenation (ECMO). However, it is debatable whether bivalirudin (BIV), a direct thrombin inhibitor, may be..
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Jan 1, 1970
Inferior and Superior Vena…
Abstract OBJECTIVES: Superior vena cava oxygen saturation (SVC O2) monitoring is well described for early detection of hemodynamic deterioration after neonatal cardiac surgery but inferior vena cava vein oxygen saturation (IVC O2) monitoring data..
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Jan 1, 1970
Use of hemoadsorption therapy…
This case reports on a 20-day old newborn (weight 3.1 kg, body surface area 0.20 m2), who was diagnosed with an extreme tetralogy of Fallot presenting in a severe cyanotic..
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Jan 1, 1970
Optimal Sweep Gas to…
Abstract The optimal setting to achieve a suitable PaCO2 value of 35–45 mmHg upon initiating cardiopulmonary bypass (CPB) in the pediatric population is undefined in the literature. Sweep gas is set..
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Jan 1, 1970
Extracorporeal Membrane Oxygenation Outcomes…
Abstract OBJECTIVE: Patient selection for pediatric extracorporeal membrane oxygenation (ECMO) support has broadened over the years to include children with pre-existing neurologic morbidities. We aimed to determine the prevalence and..
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Jan 1, 1970
Del Nido cardioplegia: from…
Abstract The increasing number of minimally invasive procedures prompted the quest for a simple and effective single shot cardioplegia to allow the surgeons to focus on their workflow. The originally..
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Jan 1, 1970
Recent advancements in pediatric…
Abstract Background Pediatric cardiac surgery is in itself very enigmatic and individualized. Presently, there has been a slew of new developments aimed primarily toward pediatric cardiopulmonary bypass for safer, patient-centered..
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Jan 1, 1970
The successful application of…
This case reports on a 6-year-old boy, who was admitted to the hospital due to prolonged dyskinetic movements resulting in rhabdomyolysis and acute kidney injury [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/08/CoW_33_2022_E-web_compressed.pdf"]
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Jan 1, 1970
Hemoadsorption for severe MIS-C…
This case reports on a 13 year old boy (weight 60 kg, height 160 cm) who presented with fever, rash, abdominal pain, and vomiting. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/08/CoW_32_2022_E_web_compressed.pdf"]
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Jan 1, 1970
Thrombosis in Extracorporeal Membrane…
Abstract Thrombosis in extracorporeal membrane oxygenation (ECMO) circuits remains a frequent complication. We characterize the location, extent, structure, and clinical implications of thrombi in 53 ECMO circuits from 46 pediatric patients...
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Jan 1, 1970
First Hemoadsorption during Cardiopulmonary…
This case reports on a 5 day old male full term newborn with congenital hypoplastic left heart syndrome who was scheduled for a corrective procedure. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/08/CoW_31_2022_E_web_compressed.pdf"]
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Jan 1, 1970
Stroke in pediatric ECMO…
Abstract Background The rates, outcomes, and long-term trends of stroke complicating the use of extracorporeal membrane oxygenation (ECMO) have been inconsistently reported. We compared the outcomes of pediatric ECMO patients..
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Jan 1, 1970
Extracorporeal membrane oxygenation in…
Abstract Hematological malignancies (HM) have been, until recently, viewed as contraindications to extracorporeal membrane oxygenation (ECMO) due to bleeding and infectious complications. However, conflicting literature regarding whether ECMO should be..
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Jan 1, 1970
Use of CytoSorb hemoadsorption…
This case reports on a 61-year-old male, who was assessed by cardiac surgery in consideration for mitral valve surgery following presentation for congestive heart failure. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/07/CoW_30_2022_E_web_compressed.pdf"]
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Jan 1, 1970
Eficacia del CytoSorb en…
Abstract El síndrome de dificultad respiratoria del adulto (SDRA) por el virus SARS-CoV-2 tiene una alta morbi-mortalidad secundaria al severo compromiso pulmonar sumado a una respuesta inmune disregulada, causal de..
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Jan 1, 1970
Hemodynamic instability is frequently…
Abstract Extracorporeal Membrane Oxygenation (ECMO) is associated with significant mortality. Provision of high-quality end-of-life (EOL) care for patients supported on ECMO entails specific physiological, pharmacological, and technical considerations. Limited guidance..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 13-year-old girl from Bangladesh, who was admitted to the hospital with incipient renal failure and hypertension. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/07/CoW_29_2022_E_web_compressed.pdf"]
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Jan 1, 1970
ECMO simulation training during…
Abstract Background: Extracorporeal membrane oxygenation (ECMO) is a supportive therapy used in the most severe forms of acute respiratory distress syndrome. Due to its intrinsic complexity and relatively low annual..
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Jan 1, 1970
Prospective clinical study testing…
Abstract Introduction During cardiopulmonary bypass (CPB), supranormal concentrations of oxygen are routinely administered with the intention to prevent cellular hypoxia. However, hyperoxemia may have adverse effects on patient outcome. Oxygen..
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Jan 1, 1970
Innominate artery direct cannulation…
Abstract Background This study aimed to investigate the safety of direct innominate arterial (IA) cannulation using a pediatric arterial cannula to establish selective antegrade cerebral perfusion (ACP) during total arch..
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Jan 1, 1970
Outcome of primary graft…
Abstract Background: Primary graft dysfunction remains the leading cause of 30-day mortality after heart transplantation. Few data have been published about the clinical outcome of severe primary graft dysfunction treated..
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Jan 1, 1970
Development of pediatric multidisciplinary…
Abstract Introduction: Pediatric extracorporeal membrane oxygenation (ECMO) is a high risk, low-volume technology. Infrequency of this technology and associated complications may translate to unfamiliarity of identification and management of potentially..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 37-year-old male patient with known type 1 diabetes mellitus, who was admitted to the hospital with nausea, multiple vomiting and abdominal pain. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/07/CoW_28_2022_E_web_compressed.pdf"]
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Jan 1, 1970
Cardiac Dysfunction Biomarkers are…
Abstract Biomarkers of cardiac dysfunction may aid in decision making about organ recovery and optimal timing of separation from extracorporeal membrane oxygenation (ECMO). We conducted a prospective observational study of..
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Jan 1, 1970
Use of CytoSorb® hemoadsorption…
Abstract Background Complex cardiac surgery and prolonged cardiopulmonary bypass are associated with significant activation of the systemic inflammatory response system. Pro-inflammatory cytokines, oxygen free radicals and complement activation products contribute..
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Jan 1, 1970
Effect of Nitric Oxide…
Abstract Importance In children undergoing heart surgery, nitric oxide administered into the gas flow of the cardiopulmonary bypass oxygenator may reduce postoperative low cardiac output syndrome, leading to improved recovery and..
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Jan 1, 1970
Intraoperative Diagnosis of Bronchovenous…
Abstract Bronchovenous (BVF) is a rare complication and can cause arterial gas embolism in vital organs, including the heart and the brain, resulting in a high mortality rate. A 51-year-old man..
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Jan 1, 1970
Use of CytoSorb hemoadsorption…
This case reports on a 28-year-old female patient who was referred intubated and ventilated from an intensive care unit (ICU) of another tertiary care hospital to Sir Gangaram Hospital, Delhi,..
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Jan 1, 1970
Human albumin and 6%…
Abstract Background A meta-analysis of randomized controlled trials was recently published in BMC Surgery that compared the use of human albumin with 6% hydroxyethyl starches 130/0.4 for cardiopulmonary bypass prime..
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Jan 1, 1970
Neuromonitoring, neuroimaging, and neurodevelopmental…
Abstract Background Brain injury and neurodevelopmental impairment remain a concern in children with complex congenital heart disease (CHD). A practice guideline on neuromonitoring, neuroimaging, and neurodevelopmental follow-up in CHD patients..
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Jan 1, 1970
Cell saver blood transfusions…
Abstract Objective Cardiopulmonary bypass (CPB) is a requisite for correction of congenital heart disease by open-heart surgery and induces a systemic inflammatory response that can lead to complications such as..
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Jan 1, 1970
Consensus Statement: Hemostasis Trial…
Abstract Background Research evaluating hemostatic agents for the treatment of clinically significant bleeding has been hampered by inconsistency and lack of standardized primary clinical trial outcomes. Clinical trials of hemostatic..
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Jan 1, 1970
Outcome of post‑traumatic acute…
Abstract We aimed to evaluate the outcomes of post‑traumatic acute respiratory distress syndrome (ARDS)in young patients with and without Extracorporeal membrane oxygenation (ECMO) support. A retrospective analysis was conducted for..
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Jan 1, 1970
Coagulation in pediatric extracorporeal…
Abstract Objectives Extracorporeal membrane oxygenation (ECMO) involves complex coagulation management and frequent hemostatic complications. ECMO practice between centers is variable. To compare results between coagulation studies, standardized definitions and clear..
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Jan 1, 1970
Renal Replacement Therapy for…
Abstract Introduction: Patients receiving extracorporeal membrane oxygenation (ECMO) often require renal replacement therapy (RRT). The challenge of inserting a dialysis catheter (DC) could be solved by direct connection of RRT lines..
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Jan 1, 1970
CytoSorb as adjuvant therapy…
This case reports on a 55-year-old male patient who was transferred from an external hospital to Immenstadt hospital due to progressive respiratory deterioration with confirmed COVID-19 pneumonia. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/06/CoW_26_2022_E_web_compressed.pdf"]
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Jan 1, 1970
Improving Trendelenburg position effectiveness…
Abstract Introduction Trendelenburg position (TP) is used to transport gaseous emboli away from the cerebral region during cardiac surgery. However, TP effectiveness has not been fully considered when combined with..
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Jan 1, 1970
The Evolution of Extracorporeal…
Abstract This systematic review summarizes the major developments in extracorporeal membrane oxygenation (ECMO) circuitry in pediatrics over the past 20 years and demonstrates the impacts of those developments on clinical..
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Jan 1, 1970
Use of the CytoSorb®…
This case reports on a 34-year-old male patient with a medical history of corrected Fallot tetralogy, who was scheduled for heart transplantation. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/06/CoW_25_2022_E_web_compressed.pdf"]
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Jan 1, 1970
Oxygen Delivery in Pediatric…
Abstract Objective Acute kidney injury (AKI) following pediatric cardiac surgery with cardiopulmonary bypass is a frequently reported complication. This study aims to determine the critical oxygen delivery (DO2i) threshold associated..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 31-year-old previously healthy female patient, who was admitted post-operatively to the intensive care unit (ICU) with hemorrhagic shock and dilutional/ disseminated intravascular coagulopathy following secondary..
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Jan 1, 1970
Pediatric Extracorporeal Membrane Oxygenation…
Abstract Extracorporeal membrane oxygenation (ECMO) support requires skills that can only be found in specialized centers. The number of patients annually supported with ECMO is positively associated with the survival..
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Jan 1, 1970
Extracorporeal membrane oxygenation in…
Abstract Introduction: Extracorporeal membrane oxygenation (ECMO) is an important treatment option for organ support in respiratory insufficiency, cardiac failure, or as an advanced tool for cardiopulmonary resuscitation. Reports on pediatric..
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Jan 1, 1970
Urgent Coronary Artery Bypass…
Blood purification by hemoadsorption therapy seems to improve outcomes in selected patients undergoing cardiac surgery with cardiopulmonary bypass. Here, we report the successful application of hemoadsorption in the severe systemic..
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Jan 1, 1970
Brain death: a clinical…
Abstract Brain death, also commonly referred to as death by neurologic criteria, has been considered a legal definition of death for decades. Its determination involves many considerations and subtleties. In..
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Jan 1, 1970
Simultaneous electrical online estimation…
Abstract Two equations have been developed from multi-frequency measurements of blood impedance Zb for a simultaneous electrical online estimation of changes in blood hematocrit ΔH [%] and temperatures ΔT [K] in cardiopulmonary bypass (CPB). Zb of fixed blood..
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Jan 1, 1970
On-Hours Compared to Off-Hours…
Abstract OBJECTIVES: We aimed to investigate whether there are differences in outcome for pediatric patients when extracorporeal life support (ECLS) is initiated on-hours compared with off-hours. DESIGN: Retrospective cohort study...
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Jan 1, 1970
Preoperative Iron Supplementation in…
Abstract Objective To assess preoperative hemoglobin and perioperative red blood cell transfusion in children undergoing cardiac surgery after the implementation of a preoperative patient blood management (PBM) clinic with oral..
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Jan 1, 1970
Impact of Heparin- or…
Abstract Background: Extracorporeal circuit coating has been shown to improve coagulation derangements during pediatric cardiopulmonary bypass (CPB). This study compared platelet function and hemostasis activation in pediatric cardiac surgery conducted with..
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Jan 1, 1970
Patient blood management in…
Abstract Objective The objective of this study was to audit current patient blood management practice in children throughout cardiac surgery and paediatric intensive care unit (PICU) admission. Design This was..
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Jan 1, 1970
Use of Cytosorb in…
This case reports on a 63-year-old male, who was admitted to the hospital with a 2-month history of exertional shortness of breath, a periodic cough with purulent sputum and right..
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Jan 1, 1970
Protective continuous ventilation strategy…
Abstract OBJECTIVES The aim of this study was to evaluate if a ‘protective’ (low-tidal/low-frequency) ventilation strategy can shorten the postoperative ventilation time and minimize acute lung injury in children..
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Jan 1, 1970
Impact of a Multidisciplinary…
Abstract Significant progress has been made in neonatal cardiopulmonary bypass (CPB) over the years. At Penn State Health Children’s Hospital, we have established a multidisciplinary research team that brings clinicians,..
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Jan 1, 1970
Cerebral Infarction During Cervical…
Abstract Veno-arterial extra-corporeal membrane oxygenation (VA ECMO) in children is often established by cannulation of the right carotid artery and the right internal jugular vein. Cerebral infarction which is sometimes..
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Jan 1, 1970
Oxidative Stress and Indicators…
Abstract Pediatric cardiac surgery induces an increased oxidative stress (OS) response. Increased OS is associated with poor neurologic outcomes in neonatal populations with similar patterns of brain injury. We investigated..
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Jan 1, 1970
Patterns and Determinants of…
Abstract Background. Children undergoing cardiac surgery with cardiopulmonary bypass (CPB) are exposed to the risk of hormonal imbalances resulting from acute stress, which may eventually result in high postoperative mortality..
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Jan 1, 1970
ECMO plus CytoSorb–are we…
Chair: Roberto Lorusso, Maastricht,The Netherlands and Federico Pappalardo, Alessandria, Italy CytoSorb + ECMO in COVID-19: latest results from the Multicenter CTC Registry Awori Hayanga, Morgantown, USA Use of CytoSorb and..
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Jan 1, 1970
Successful treatment of severe…
A 64-year-old female was admitted to the Emergency Department after she was found somnolent by her daughter [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/05/CoW_21_2022_E_web_compressed.pdf"]
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Jan 1, 1970
Comparison of the predictive…
Abstract Background This study aims to compare lactate and central venous blood gas in the prediction of outcome in pediatric venoarterial mode extracorporeal membrane oxygenation (V-A ECMO). Method This was..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 53-year-old male patient who was transferred from a peripheral hospital to Ordensklinikum Linz with initial manifestation of Hodgkin‘s disease (stage IV/B/E, lymph nodes neck, bulks..
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Jan 1, 1970
Veno-arterial extracorporeal membrane oxygenation…
Abstract Background and Aim of the Study Acute cardiovascular failure remains a leading cause of death in severe poisonings. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has been increasingly used as a..
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Jan 1, 1970
Centrifugal Pump Generates Superior…
Abstract Purpose With newer generation diagonal and centrifugal blood pumps gaining popularity, the objective of this study was to compare the DP3-i-cor diagonal and RotaFlow centrifugal pumps in terms of..
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Jan 1, 1970
Feasibility of non-invasive neuro-monitoring…
Abstract Introduction Detection of neurological complications during extracorporeal membrane oxygenation (ECMO) may be enhanced with non-invasive neuro-monitoring. We investigated the feasibility of non-invasive neuro-monitoring in a paediatric intensive care (PIC)..
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Jan 1, 1970
Intracranial haemorrhage in adult…
Abstract Aims Intracranial haemorrhage (ICH) is one of the most serious complications of adult patients treated with venoarterial extracorporeal membrane oxygenation (VA-ECMO) and is associated with increased morbidity and mortality...
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Jan 1, 1970
Development of a Model…
Abstract Pediatric cardiac extracorporeal membrane oxygenation (ECMO) patients have high mortality rates. The purpose of our study was to develop and validate the Pediatric Survival After Veno-arterial ECMO (Pedi-SAVE) score for predicting..
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Jan 1, 1970
Rescue venovenous extracorporeal membrane…
Abstract Background Twenty percent of pediatric patients with BA develop ACLF with increased mortality while awaiting LT. Respiratory complications are common in pediatric ACLF and are associated with increased morbidity..
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Jan 1, 1970
Impaired Blood Flow? Tension…
Abstract A 55-year-old patient experiencing severe coronavirus disease 19 (COVID-19) related acute refractory respiratory failure requiring venovenous extracorporeal membrane oxygenation (VV-ECMO) support, with femoro-femoral approach, suddenly developed both signs of..
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Jan 1, 1970
Use of CytoSorb as…
This case reports on a 67-year-old male patient, who was admitted to hospital suffering from a severe immunological response following his 2nd COVID-19 vaccination. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/05/CoW_19_2022_E_web_compressed.pdf"]
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Jan 1, 1970
Prothrombin Complex Concentrates to…
Abstract Various factors may lead to coagulation disturbances following cardiopulmonary bypass and surgery for congenital heart disease. In addition to the risks associated with the administration of allogeneic blood products,..
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Jan 1, 1970
Waitlist Outcomes for Children…
Abstract Background We evaluated the impact of pediatric heart-allocation policy changes over time and the approval of the Berlin ventricular assist device (VAD) on waitlist (WL) outcomes for children with..
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Jan 1, 1970
Management of Circuit Air…
Abstract Air in circuit in patients receiving extracorporeal membrane oxygenation (ECMO) is an emergency. Different protocols have been suggested to deal with this rare but fatal complication, but their efficacies..
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Jan 1, 1970
Routine Neuroimaging: Understanding Brain…
Abstract OBJECTIVES: This project aims to describe brain injuries on routine neuroimaging in a large single-center neonatal and pediatric cohort supported by extracorporeal membrane oxygenation. The study also aims to..
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Jan 1, 1970
Combined Application of CytoSorb…
A 41- year-old male patient with no pathological history presented to the hospital with colic-type abdominal pain in the right hypochondrium associated with a history of fever over a few..
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Jan 1, 1970
Pediatric heart harvest
Surgical technique of pediatric heart harvest in patient with previous antrolateral thoracotomy and unfortunately brain death heart was used for transplantation because of absence of other associated anomalies and neither..
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Jan 1, 1970
Case Report of a…
Abstract Hypoxemic arrests due to severe traumatic pulmonary injury may not respond to usual medical support. Extracorporeal life support (ECLS) can be life-saving; adequate flows are needed in this setting..
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Jan 1, 1970
Measuring the Resting Energy…
Abstract Both overfeeding and underfeeding critically ill children are problematic. This prospective pilot study evaluated the resting energy expenditure in infants and children requiring extracorporeal membrane oxygenation (ECMO) support. An..
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Jan 1, 1970
Pump-controlled retrograde trial off…
Abstract Background The optimal strategy of weaning veno-arterial (V-A) extracorporeal membrane oxygenation (ECMO) remains poorly described. Pump-controlled retrograde trial off (PCRTO) involves serial decremental pump revolutions until a retrograde flow..
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Jan 1, 1970
How to avoid rapid…
Abstract Background: Venovenous ECMO is a lifesaving technique for patients with severe respiratory failure. Management of carbon dioxide (CO2) levels at ECMO start is crucial, as recent studies found an association..
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Jan 1, 1970
Initial results from an…
Abstract Background Over recent years, a number of enhanced recovery programs have appeared in first, adult colorectal surgery, and subsequently many other adult surgical specialties. Increasing interest in this approach..
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Jan 1, 1970
Validation of the Masimo…
Abstract We assessed the accuracy of Masimo O3™ regional cerebral oxygen saturation (rSO2) readings by comparing them with reference values and evaluated the relationship between rSO2 and somatic tissue oxygen saturation..
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Jan 1, 1970
Does the Volume and…
Abstract Pediatric patients, especially neonates and infants, undergoing cardiac surgery, are at particularly high risk for developing surgical bleeding. After separation from cardiopulmonary bypass (CPB), excessive bleeding in children frequently..
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Jan 1, 1970
38th Annual Children’s National…
Abstract Introduction: Pediatric extracorporeal membrane oxygenation (ECMO) is a high risk, low-volume technology. Infrequency of this technology and associated complications may translate to unfamiliarity of identification and management of potentially..
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Jan 1, 1970
Association of Ventilator Settings…
Abstract Extracorporeal life support (ECLS) is a treatment for acute respiratory failure that can provide extracorporeal gas exchange, allowing lung rest. However, while most patients remain mechanically ventilated during ECLS,..
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Jan 1, 1970
The Myocardial Protective Effects…
Abstract Background We investigated the myocardial protective effect of a moderate-potassium cold blood cardioplegic solution (K+, 10 mmol/L) in pediatric cardiac surgery. Methods Sixty-eight pediatric patients with congenital heart disease..
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Jan 1, 1970
Oxygenator impact on peramivir…
Abstract Introduction This study aims to determine the oxygenator impact on alterations of peramivir (PRV) in a contemporary neonatal/pediatric (1/4-inch) and adolescent/adult (3/8-inch) extra-corporeal membrane oxygenation (ECMO) circuit including the..
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Jan 1, 1970
CytoSorb® usage in a…
A 66-year-old male patient presented to the hospital with complaints of left sided chest pain radiating to left arm for 1 week as well as acute/severe pain over the last..
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Jan 1, 1970
Assessment of cardiac recovery…
Abstract Aims Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly being used to support patients in cardiogenic shock (CS). Early determination of disposition is paramount, as longer durations of support have..
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Jan 1, 1970
Functional Status Change Among…
Abstract In our retrospective multicenter study of patients 0 to 18 years of age who survived extracorporeal life support (ECLS) between January 2010 and December 2018, we sought to characterize..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 54-year-old female patient with a known medical history of diabetes mellitus, hypertension and acute gastroenteritis, who was admitted to the hospital with tachycardia (145/min), tachypnea..
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Jan 1, 1970
Comparison between Del Nido…
Abstract Background Del Nido cardioplegia (DNc) was designed for superior myocardial protection during cardiopulmonary bypass (CPB). We conducted a retrospective review to explore if DNc was associated with increase in..
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Jan 1, 1970
Absorbable sutures for cardiopulmonary…
Abstract Background Absorbable sutures, commonly used in general surgery, are not routinely used as purse strings for arterial and venous cannulation for cardiopulmonary bypass in pediatric heart surgery. The general concern..
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Jan 1, 1970
Extracorporeal Membrane Oxygenation in…
Abstract Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and lung involvement is common. Patients with COVID-19 may progress to acute respiratory distress syndrome..
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Jan 1, 1970
A Randomized Clinical Trial…
Abstract Background The objective of this randomized clinical trial was to investigate the effects of perfusion modalities on cerebral hemodynamics, vital organ injury, quantified by the Pediatric Logistic Organ Dysfunction-2..
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Jan 1, 1970
Rapid reduction of substantially…
This case reports on a 24-year-old, initially healthy male patient, who suffered a knee dislocation due to a sports trauma. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/04/CoW_15_2022_E_web_compressed.pdf"]
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Jan 1, 1970
Blood pressure variability during…
Abstract Background Blood pressure variability (BPV), defined as the degree of variation between discrete blood pressure readings, is associated with poor outcomes in acute care settings. Acute kidney injury (AKI)..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 35-year-old female patient with systemic lupus erythematosus who presented to hospital with exacerbated encephalopathy under the assumption of an infection after she was found apathetic,..
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Jan 1, 1970
Association Between Hyperoxemia and…
Abstract OBJECTIVES: To determine potential risk factors for severe hemolysis during pediatric cardiopulmonary bypass and examine whether supraphysiologic levels of oxygen and cardiopulmonary bypass duration are associated with hemolysis. DESIGN: ..
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Jan 1, 1970
Case Report: Prevention of…
This case reports on a 12-year-old boy, who was hit by a motorcycle while riding his bicycle. The motorcycle ran over the boy’s legs causing an open wound in the..
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Jan 1, 1970
Percutaneous Pulmonary Artery Cannulation…
Abstract Right heart failure (RHF) is a common, yet difficult to manage, complication of severe acute respiratory distress syndrome requiring extracorporeal membrane oxygenation (ECMO) that is associated with increased mortality. Reports..
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Jan 1, 1970
VA-ECMO rescue therapy in…
Abstract Introduction Propofol infusion syndrome (PRIS) is a rare entity that could lead to profound cardiogenic shock (CS). Mitochondrial toxicity and sympathetic blockade are the mechanisms leading to CS in..
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Jan 1, 1970
ISICEM 2022 CytoSorbents Symposium:…
- Hemoadsorption with CytoSorb as part of an individualized therapy in critically-ill patients Chair: Manu Malbrain, Leuven, Belgium and Yatin Mehta, Gurgaon, India - How to balance sepsis campaign guidelines..
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Jan 1, 1970
Mechanical ventilation during cardiopulmonary…
Abstract OBJECTIVES Cardiopulmonary bypass generates a systemic inflammatory response. This inflammatory response is reduced if patients are ventilated during bypass, as evidenced by lower levels of postoperative circulating inflammatory..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 60-year-old male patient who presented to hospital for elective surgical treatment of carcinoma of the pancreatic head. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/02/CoW_12_2022_E_web_compressed.pdf"]
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Jan 1, 1970
Early Implantation of Extracorporeal…
Abstract Extracorporeal membrane oxygenator (ECMO) is effective for maintaining oxygenation and hemodynamic support in patients with post-cardiotomy cardiogenic shock (PCCS). Researchers, led by Ahmed Abdeljawad, sought to compare the effect..
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Jan 1, 1970
Extracorporeal membrane oxygenation in…
Abstract During the first wave of the COVID-19 pandemic, the European Extracorporeal Life Support Organization (ELSO) established a prospective survey including 52 European neonatal and paediatric centres and reported the..
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Jan 1, 1970
Corona, Acute Ischemic Stroke,…
This case reports on a 29-year-old man with diabetes mellitus, who presented to the emergency department with complaints of left sided upper limb and lower limb weakness associated with altered..
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Jan 1, 1970
The myocardial protective effects…
Abstract Objective: Adenosine pretreatment reduces injury caused by ischemia-reperfusion. To investigate the hypothesis that adenosine pretreatment would modulate injury induced by cardiopulmonary bypass (CPB) and myocardial ischemia/reperfusion, we conducted a randomized..
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Jan 1, 1970
The association between end-tidal…
Abstract Introduction: Evidence suggests the high capability of non-invasive assessment of the End-tidal carbondioxide (ETCO2) in predicting changes in arterial carbon dioxide pressure (PCO2) following major surgeries in children. We aimed..
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Jan 1, 1970
Effectiveness of hemoadsorption therapy…
A previously healthy 51-year-old male patient was admitted to the National Hospital’s Emergency Department with a clinical picture and a 6 days evolution of symptoms characterized initially by intense frontal..
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Jan 1, 1970
Single-pass albumin dialysis and…
This case reports on a 13-year-old boy, who was admitted to the hospital for coryzal symptoms (acute inflammation of the upper respiratory tract) and chest pain. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/03/CoW_09_2022_E_web_compressed.pdf"]
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Jan 1, 1970
A systematic review of…
Abstract Objectives:To determine the optimal antithrombotic agent choice, timing of initiation, dosing and duration of therapy for paediatric patients undergoing cardiac surgery with cardiopulmonary bypass. Methods:We used PubMed and EMBASE..
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Jan 1, 1970
Use of CytoSorb as…
This case reports on a 44-year-old female, who was admitted to the hospital with complaints of high fever, vomiting, abdominal pain and decreased urine output for the previous 2 days...
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Jan 1, 1970
Kinetics of Bilirubin and…
This case reports on a 61-year-old woman with confirmed COVID-19, who was admitted to a different hospital with a productive cough that she had had for a few days. [pdf-embedder..
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Jan 1, 1970
Evaluating the Impact of…
Abstract Objectives Cardiopulmonary bypass (CPB) predisposes young children to coagulopathy. The authors evaluated possible effects of CPB priming fluids on perioperative bleeding in pediatric cardiac surgery. Design Meta-analysis and systematic..
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Jan 1, 1970
Extracorporeal Life Support Organization…
Abstract Disclaimer: This extracorporeal life support organization guideline describes the preparation for and undertaking of transport and retrieval of patients on extracorporeal membrane oxygenation (ECMO). The guideline describes useful and..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 58-year-old male patient who presented to the hospital for an elective cardiothoracic surgical procedure. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/12/CoW_06_2022_E_web_compressed.pdf"]
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Jan 1, 1970
The Fundamental Skills and…
Abstract Perfusion education programs use simulation to provide students with clinical skills prior to entering the operating room. To teach the psychomotor execution of skills in a simulation lab requires..
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Jan 1, 1970
Effect of CPB Glucose…
Abstract Background: Systemic inflammatory response syndrome (SIRS) is a common complication after cardiac surgery. There are no definite optimal glycemic threshold for pediatric patients receiving open-heart surgery with CPB. The..
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Jan 1, 1970
Plasma and Platelet Transfusions…
Abstract Objectives: To present the recommendations and consensus statements with supporting literature for plasma and platelet transfusions in critically ill neonates and children undergoing cardiac surgery with cardiopulmonary bypass or..
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Jan 1, 1970
Technical note: Novel use…
This case reports on an initially healthy 59-year-old patient, who was hospitalized following a serious burn trauma. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/02/CoW_05_2022_E_web_compressed.pdf"]
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Jan 1, 1970
Association of Arterial Hyperoxia…
Abstract Importance Oxygen supplementation is a cornerstone treatment in pediatric critical care. Accumulating evidence suggests that overzealous use of oxygen, leading to hyperoxia, is associated with worse outcomes compared with patients..
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Jan 1, 1970
Extracorporeal Membrane Oxygenation for…
Abstract Extracorporeal membrane oxygenation (ECMO) is a rescue treatment used in children and adults with reversible cardiorespiratory failure. The role of ECMO is not fully established in pediatric sepsis. In..
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Jan 1, 1970
New Publication Reports Significant…
MONMOUTH JUNCTION, N.J., Jan. 24, 2022 /PRNewswire/ -- (NASDAQ: ), a leader in the treatment of life-threatening conditions in the intensive care unit and cardiac surgery using blood purification, highlights a new publication in..
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Jan 1, 1970
ELSO Guidelines for Adult…
Abstract This guideline describes the ECMO circuit for all patient populations. These guidelines describe safe practice based on extensive experience and are considered consensus guidelines. These guidelines are not intended..
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Jan 1, 1970
Tracheostomy Practices and Outcomes…
Abstract Objectives: Children receiving prolonged extracorporeal membrane oxygenation (ECMO) support may benefit from tracheostomy during ECMO by facilitating rehabilitation; however, the procedure carries risks, especially hemorrhagic complications. Knowledge of tracheostomy practices and outcomes of..
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Jan 1, 1970
Postoperative use of CytoSorb…
This case report’s on a 65-year-old male patient who was admitted to the Department of Cardiac Surgery due to severe mitral regurgitation in the context of infective endocarditis. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/01/CoW_04_2022_E_web_compressed.pdf"]
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Jan 1, 1970
2021 ELSO Adult and…
Abstract Anticoagulation is necessary for most pediatric and adult extracorporeal membrane oxygenation (ECMO) patients to prevent circuit clotting. Inherently, the most common side effect of anticoagulation is bleeding. Anticoagulation during..
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Jan 1, 1970
Somatic Support with Veno-venous…
Abstract Supporting homeostasis in a pregnant woman with brain death to achieve fetal viability is called somatic support. We present a case of young pregnant woman at 21 weeks’ gestation..
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Jan 1, 1970
Hemoadsorption as bridge to…
This case reports on a 6-month-old female patient (8 kg, 55 cm), who was admitted to the hospital due to severe hyperbilirubinemia. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/01/CoW_03_2022_E_web_compressed.pdf"]
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Jan 1, 1970
Vacuum-assisted venous drainage, angel…
Abstract Vacuum-assisted venous drainage (VAVD) was proposed to optimize venous drainage during bypass through femoral venous cannulation. It is currently used in both adult and pediatric surgery when siphon gravity..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 54-year-old male patient with known arterial hypertension who was transferred from a peripheral hospital to the National Hospital with cough and progressive respiratory distress 6..
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Jan 1, 1970
Antithrombin III infusion improves…
Abstract Purpose Achieving effective anticoagulation during neonatal extracorporeal membrane oxygenation (ECMO) without increasing the risk of hemorrhage remains challenging. The use of antithrombin III (AT-III) for this purpose has been..
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Jan 1, 1970
Use of Extracorporeal Membrane…
Abstract Objectives: To describe the use of extracorporeal membrane oxygenation (ECMO) in the management of pediatric poisoning in the United States and to identify predictors of mortality. Design: Retrospective cohort study. Setting: ..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 60-year-old male diagnosed with COVID-19 following a positive RT-PCR test, who was hospitalized with complaints of cough with mild expectoration, and worsening shortness of breath..
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Jan 1, 1970
Delirium in Children After…
Abstract Background Delirium is acute brain dysfunction associated with serious illness. Emerging data indicate that delirium occurs in greater than 20% of children in pediatric intensive care units. Cardiac bypass..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 37-year-old female with previous Lower Segment Cesarean Section (LSCS) and a history of gestational insulin-dependent diabetes mellitus, who was admitted to hospital at 32 weeks..
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Jan 1, 1970
Cytokine hemoadsorption in the…
A 35-year-old pregnant woman (gestational age 32 weeks) admitted to hospital due to COVID-19 pneumonia and severe respiratory failure. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/12/CoW_50_2021_E_web_compressed.pdf"]
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Jan 1, 1970
Pediatric Extracorporeal Life Support…
Abstract This retrospective cohort study describes all children transported on extracorporeal life support (ECLS) by the Stollery Children’s Hospital Pediatric Transport team (SCH-PTT) between 2004 and 2018. We compared outcomes..
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Jan 1, 1970
Le prime linee guida…
Abstract È l’Ospedale Pediatrico Bambino Gesù, in collaborazione con 5 società scientifiche internazionali, a mettere per la prima volta a disposizione di rianimatori e oncoematologi le Linee Guida per il trattamento con ossigenazione extracorporea..
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Jan 1, 1970
Extracorporeal membrane oxygenation in…
Abstract Use of extracorporeal membrane oxygenation (ECMO) in children receiving haematopoietic cell transplantation (HCT) and immune effector cell therapy is controversial and evidence-based guidelines have not been established. Remarkable advancements..
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Jan 1, 1970
Use of hemoadsorption therapy…
This case reports on a 20-day old newborn (weight 3.1 kg, body surface area 0.20 m2), who was diagnosed with an extreme tetralogy of Fallot presenting in a severe cyanotic..
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Jan 1, 1970
Left Heart Decompression on…
Abstract OBJECTIVES: To describe the association between left heart decompression on veno-arterial extracorporeal membrane oxygenation and survival in patients with myocarditis and dilated cardiomyopathy. The secondary outcome is to study..
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Jan 1, 1970
Pediatric ECMO: unfavorable outcomes…
Abstract Background Inflammatory and endothelial activation responses during extracorporeal membrane oxygenation (ECMO) support in children are poorly understood. In this study, we aimed to determine if circulating inflammatory, endothelial activation,..
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Jan 1, 1970
Efficacy and safety of…
Abstract BACKGROUND The relicensing of aprotinin in Europe and Canada has stimulated discussions on its usefulness in paediatric cardiac surgery. OBJECTIVE To systematically evaluate the available evidence on the efficacy..
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Jan 1, 1970
The effect of selective…
Abstract Background Suboptimal tissue perfusion and oxygenation may be the root cause of certain perioperative complications in neonates and infants having complicated aortic coarctation repair. Practical, effective, and real-time monitoring..
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Jan 1, 1970
Impact of Arterial Carbon…
Abstract Background Cerebral autoregulation (CA) impairment is associated with neurological complications among children supported by extracorporeal membrane oxygenation (ECMO). Severe variations of arterial CO2 (PaCO2) and O2 (PaO2) tension after ECMO onset..
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Jan 1, 1970
How Dose Body Water…
Abstract Introduction: Although the management of body water balance on cardiac surgery with cardiopulmonary bypass (CPB), especially in children, is essential, little is known how body water composition changes around CPB...
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 49-year-old female patient who presented to hospital with locally advanced carcinoma of the pancreatic head with jaundice, weight loss, abdominal pain and ascites already manifested...
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Jan 1, 1970
The Anesthesiologist’s Perspective and…
Abstract Anesthesiologists are important components of volunteer teams which perform congenital cardiac surgery in low-resource settings throughout the world, but limited data exist to characterize the nature and breadth of..
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Jan 1, 1970
Characterizing Sleep Disruption and…
Abstract OBJECTIVES: Patients in the pediatric cardiac ICU are frequently exposed to pharmacologic and environmental factors that predispose them to sleep disturbances and may increase the risk of delirium. In..
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Jan 1, 1970
Successful treatment of severe…
A 60-year-old female was admitted to the Emergency Department after she was found unconscious by her husband. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/10/CoW_47_2021_E_web_compressed.pdf"]
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Jan 1, 1970
CytoSorb in a patient…
This case reports on a 47-year-old male who was admitted to the Emergency Room with tachypnea, hypotension, and post-COVID-19 mucormycosis. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/11/CoW_46_2021_E_web_compressed.pdf"]
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Jan 1, 1970
Pharmacokinetics of Antibiotics in…
Abstract Children show important developmental and maturational changes, which may contribute greatly to pharmacokinetic (PK) variability observed in pediatric patients. These PK alterations are further enhanced by disease-related, non-maturational factors...
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Jan 1, 1970
Ex Vivo Allograft Perfusion…
Abstract Background Pediatric heart transplant (HTx) recipients with congenital heart defects require complex concomitant surgical procedures with the risk of prolonging the allograft’s ischemic time. Ex vivo allograft perfusion with the..
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Jan 1, 1970
Blood purification during valve…
This case reports on a 15-year old boy with history of bicuspid valve and mild aortic valve regurgitation, who had a recent history of abdominal pain, diarrhea, and vomiting. [pdf-embedder..
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Jan 1, 1970
Education of Children With…
Abstract Background The aim of the study was to evaluate the educational achievement of patients diagnosed with physiology (UVHP) or transposition of the (TGA) after neonatal cardiac surgery. Methods An exploratory online..
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Jan 1, 1970
Impact of Corticosteroids on…
Abstract Background Corticosteroids suppress the inflammatory response to in children undergoing cardiac surgery. What is less clear is the impact of corticosteroids on the postoperative course. Methods A systematic review and..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 67-year-old male patient who was transferred from the emergency department to the multidisciplinary intensive care unit due to severe respiratory failure from a newly diagnosed..
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Jan 1, 1970
Postoperative Hematocrit and Adverse…
Abstract BACKGROUND: We sought to examine potential associations between pediatric postcardiac surgical hematocrit values and postoperative complications or mortality. METHODS: A retrospective, cross-sectional study from the Society of Thoracic Surgeons..
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Jan 1, 1970
Outcomes of Pediatric Patients…
Abstract Background: Extracorporeal membrane oxygenation (ECMO) is increasingly utilized for pediatric sepsis unresponsive to steroids and inotropic support. Outcomes of children with sepsis are influenced by the type of pathogen causing..
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Jan 1, 1970
CytoSorb® Hemoadsorption as a…
This case reports on a 59-year-old SARS-CoV-2 positive male patient with a history of chronic lymphocytic leukemia (CLL), who was transferred from an external hospital to the intensive care unit..
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Jan 1, 1970
Association Between Exogenous Nitric…
Abstract Objective To compare the incidence and severity of acute kidney injury following open heart surgery with cardiopulmonary bypass in children after administration of exogenous nitric oxide. Design Retrospective cohort..
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Jan 1, 1970
A pumpless artificial lung…
Abstract Background Artificial lungs have the potential to serve as a bridge to transplantation or recovery for children with end-stage lung disease dependent on extracorporeal life support, but such devices..
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Jan 1, 1970
Antifibrinolytic Drugs for the…
Abstract BACKGROUND: Bleeding is one of the commonest complications affecting children undergoing cardiac surgery on cardiopulmonary bypass. Antifibrinolytic drugs are part of a multifaceted approach aimed at reducing bleeding, though..
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Jan 1, 1970
Residual Lesion Diagnostics in…
Abstract Background: To assess the impact of diagnostic procedures in identifying residual lesions during extracorporeal membrane oxygenation (ECMO) on survival after pediatric cardiac surgery. Methods: Between January 2012 and December..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 76-year-old male patient who was admitted to Emden Hospital by ambulance due to progressive deterioration in his general condition accompanied by loss of strength and..
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Jan 1, 1970
Strategies to Prevent Acute…
Abstract Background and objectives AKI is a common complication after pediatric cardiac surgery and has been associated with higher morbidity and mortality. We aimed to compare the efficacy of available pharmacologic..
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Jan 1, 1970
Bi-Caval Dual Lumen Catheter…
Abstract An 11-year-old female patient was admitted to a pediatric intensive care unit for the treatment of acute respiratory distress syndrome (ARDS). She had received peripheral blood stem cell transplantation..
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Jan 1, 1970
Interrelations of Intraoperative Changes…
Abstract Objectives The monitoring of cerebral tissue oxygen saturation by near-infrared spectroscopy (ScerebO2) is used widely in pediatric cardiac anesthesia. However, little information is available on the effects of changes..
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Jan 1, 1970
EuroELSO Webinar: Anticoagulation monitoring…
EuroELSO Webinar on 30 March 2021 Topic: Anticoagulation monitoring on ECMO in neonates and children: moving target - anti Xa over ACT & APTT. Introduction, moderation & closing..
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Jan 1, 1970
Risk Factors of Venoarterial…
Abstract To analyze the risk factors for intracranial hemorrhage (ICH) in congenital heart disease (CHD) patients supported with venoarterial extracorporeal membrane oxygenation (VA-ECMO). We performed a retrospective analysis of VA ECMO patients..
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Jan 1, 1970
Routine Neuroimaging. Understanding Brain…
Abstract Objectives: This project aims to describe brain injuries on routine neuroimaging in a large single-center neonatal and pediatric cohort supported by extracorporeal membrane oxygenation. The study also aims to..
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Jan 1, 1970
Repeat Extracorporeal Membrane Oxygenation…
Abstract Objective: Children requiring multiple consecutive extracorporeal membrane oxygenation (ECMO) runs likely have ongoing cardiac pathology (eg, residual lesions, myocardial dysfunction) and are exposed to increased complications and end-organ failure...
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 54-year-old female patient who initially presented to the Emergency Department of a peripheral hospital with dyspnea and reduced general condition. Following temporary inpatient admission and..
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Jan 1, 1970
Early biochemical markers in…
Abstract Our aim was to evaluate biochemical markers in plasma (NGAL, CysC) and urine (NGAL, KIM-1) in children's early onset of acute kidney injury after congenital heart defect surgery using..
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Jan 1, 1970
Repeat Extracorporeal Membrane Oxygenation…
Abstract Objective: Children requiring multiple consecutive extracorporeal membrane oxygenation (ECMO) runs likely have ongoing cardiac pathology (eg, residual lesions, myocardial dysfunction) and are exposed to increased complications and end-organ failure...
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Jan 1, 1970
Use of CytoSorb in…
The case reports on a 17-year-old boy (weight 70 kg) transferred to the Children Infections Research Center intensive care unit (ICU) with severe jaundice and in a poor general condition..
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Jan 1, 1970
International survey of neuromonitoring…
Abstract Background: Adverse neurological events during extracorporeal membrane oxygenation (ECMO) are common and may be associated with devastating consequences. Close monitoring, early identification and prompt intervention can mitigate early and..
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Jan 1, 1970
Biomarkers for Adverse Lung…
Abstract OBJECTIVES: Cardiopulmonary bypass triggers systemic inflammation, resulting in lung injury, and frequently leads to prolonged mechanical ventilation. Biomarkers of systemic inflammation are required to predict the risk of such..
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Jan 1, 1970
Methylprednisolone Plasma Concentrations During…
Abstract Introduction: To our knowledge, methylprednisolone pharmacokinetics and plasma concentrations have not been comprehensively investigated in children with congenital heart disease undergoing cardiac surgery with cardiopulmonary bypass. It is unknown whether..
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Jan 1, 1970
Timing of congenital cardiac…
Abstract We report a series of four patients with CHD who tested positive for COVID-19, got treated, and underwent cardiac surgery in the same sitting. All had an uneventful perioperative..
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Jan 1, 1970
A Communication Guide for…
Abstract Decision-making surrounding extracorporeal membrane oxygenation initiation and decannulation has become a key challenge in critical care. Nuanced communication skills and transparent discussions about prognosis are imperative during this lifesaving,..
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Jan 1, 1970
Sublingual Microcirculatory Evaluation of…
This case reports on a 83-year-old man, with a history of type 2 diabetes, hypertension, atrial fibrillation, and myocardial infarction, who was admitted to the intensive care unit (ICU) after..
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Jan 1, 1970
Safety and utility of…
Abstract Introduction: Modified ultrafiltration (MUF) is employed at the termination of cardiopulmonary bypass (CPB) in pediatric and neonatal patients undergoing congenital heart surgery to reduce the accumulation of total body..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 34-year-old previously healthy male patient, who was admitted to the hospital due to massive amlodipine overdose. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/09/CoW_38_2021_E_web_compressed.pdf"]
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Jan 1, 1970
Blood pressure variability during…
Abstract Background Blood pressure variability (BPV), defined as the degree of variation between discrete blood pressure readings, is associated with poor outcomes in acute care settings. Acute kidney injury (AKI)..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 16-year-old male patient (weight 56 kg), who was admitted from the hematology-oncology ward to the Pediatric Intensive Care Unit (PICU) after a clinical deterioration with..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 75-year-old male patient who was admitted to the emergency department with complaints of fever, generalized weakness, signs of chest congestion, coughing and breathing difficulties since..
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Jan 1, 1970
The Albumin-to-Fibrinogen Ratio Independently…
Abstract Background: Acute kidney injury (AKI) is a common and serious complication faced by children following ventricular septal defect (VSD) surgery with cardiopulmonary bypass (CPB). The objective of this study was..
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Jan 1, 1970
Centrifugal and Roller Pumps…
Abstract Extracorporeal membrane oxygenation (ECMO) is an invaluable means of supporting critically ill children with refractory respiratory or cardiac failure. Controversy remains; however, whether roller or centrifugal pumps are superior,..
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Jan 1, 1970
Priming solution for neonatal…
Abstract The Priming volume of the oxygenators has been reduced by 75% during the last two decades and it is now possible to go safely on bypass with a priming..
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Jan 1, 1970
Nomenclature for Pediatric and…
Abstract Substantial progress has been made in the standardization of nomenclature for paediatric and congenital cardiac care. In 1936, Maude Abbott published her Atlas of Congenital Cardiac Disease, which was..
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Jan 1, 1970
Immunoadsorption therapy for a…
This case reports on a 10-year-old female patient, who was admitted to the emergency department with purpuric rash and confusion. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/09/CoW_35_2021_E_web_compressed.pdf"]
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Jan 1, 1970
C-reactive protein and procalcitonin…
Abstract Introduction To assess the efficacy of C-reactive protein (CRP) and procalcitonin (PCT) at identifying infection in children after congenital heart surgery (CHS) with cardiopulmonary bypass (CPB). Materials and Methods..
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Jan 1, 1970
Impact on Renal Function…
Abstract During cardiopulmonary bypass (CPB), high flows can allow an adequate perfusion to kidneys, but, on the other hand, they could cause emboli production, increased vascular pressure, and a more..
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Jan 1, 1970
Intraoperative use of CytoSorb…
This case reports on a 18-year-old male patient, who was admitted to a secondary hospital due to febrile symptoms (38.5-39°C) and headache with deterioration of his neurological status (bradypsychia, deviation..
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Jan 1, 1970
Novel Use of Extracorporeal…
This case reports on a 53-year-old male patient with primary refractory high-grade B-cell lymphoma, who was hospitalized to undergo Chimeric Antigen Receptor (CAR) T-cell therapy. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/07/CoW_33_2021_E_web_compressed.pdf"]
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Jan 1, 1970
Similar frequency of atrial…
Abstract Purpose: Complications associated with use of dual-lumen venovenous extracorporeal membrane oxygenation (VV-ECMO) cannulas are of concern in pediatric patients. While the risk of atrial perforation is believed to be..
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Jan 1, 1970
Cefazolin prophylaxis in children…
Abstract OBJECTIVES To determine the recommended concentrations of cefazolin to be used for antibiotic prophylaxis during paediatric cardiac surgery with extracorporeal circulation (ECC). METHODS Twenty paediatric patients undergoing cardiac surgery..
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Jan 1, 1970
Transfusion Practices in Pediatric…
Abstract Objectives: To describe blood component usage in transfused children with congenital heart disease undergoing cardiopulmonary bypass surgery across perioperative settings and diagnostic categories. Design: Datasets from U.S. hospitals participating..
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Jan 1, 1970
The Effect of Optimized…
Abstract Objective: This study aims to investigate the effect of optimized ultrafiltration on perioperative electrolytes, acid–base balance, and pulmonary function during cardiopulmonary bypass (CPB) in infants with low body weight (under..
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Jan 1, 1970
Oxidative stress response in…
Abstract Introduction Cardiac surgery (CS) in pediatric patients induces an overt oxidative stress (OS) response. Children are particularly vulnerable to OS related injury. The immaturity of their organs and antioxidant..
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Jan 1, 1970
A Trip to the…
Donation after Circulatory Death (DCD) is gaining worldwide acceptance as an adjunct to brain death (BD) in transplant surgery. Initially performed for abdominal organs procurement, DCD was then carried out..
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Jan 1, 1970
Extracorporeal Membrane Oxygenation for…
Abstract Evidence for the use of extracorporeal membrane oxygenation (ECMO) in children with refractory respiratory failure or shock following ingestion or toxin exposure, has been confined to single-center experiences, individual..
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Jan 1, 1970
Recombinant Factor VIIa in…
Abstract Objectives Recombinant factor VIIa is used off-label for refractory bleeding after cardiac surgery. This study reviewed the indications, usage rates and complications of recombinant factor VIIa. Design Retrospective case..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 40-year-old-female who was hospitalized with signs of respiratory distress due to SARS-CoV-2 infection. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/08/CoW_32_2021_E_web_compressed.pdf"]
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Jan 1, 1970
Hemadsorption as a treatment…
This case reports on a 17-year-old male patient with a history of fever, dyspnea, diffuse chest and abdominal pain, and generalized rash following COVID-19 molecular diagnosis. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/08/CoW_31_2021_E_web_compressed.pdf"]
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Jan 1, 1970
Multisite Veno-Venous Cannulation for…
Abstract OBJECTIVES: Neonates with respiratory failure are ideally supported with veno-venous rather than veno-arterial extracorporeal membrane oxygenation due to the reduced rate of neurologic complications. However, the proportion of neonates..
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Jan 1, 1970
Extracorporeal Life Support Organization…
Abstract Neonates and children who have survived critical illness severe enough to require extracorporeal membrane oxygenation (ECMO) are at risk for neurologic insults, neurodevelopmental delays, worsening of underlying medical conditions,..
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Jan 1, 1970
Association of perfusate oxygenation…
Abstract Background Little is known regarding whether hyperoxic reoxygenation was associated with higher risk of cardiovascular disorder following tetralogy of Fallot repair. Methods We performed a nested case–control study among..
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Jan 1, 1970
Tricuspid valve bacterial endocarditis…
Patient with tricuspid valve bacterial endocarditis and vegetation in pediatric population. Beating on pump total inflow. [gallery ids="17859,17868,17865,17862,17856,17853"] Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center as..
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Jan 1, 1970
The Albumin-to-Fibrinogen Ratio Independently…
Abstract Background: Acute kidney injury (AKI) is a common and serious complication faced by children following ventricular septal defect (VSD) surgery with cardiopulmonary bypass (CPB). The objective of this study was..
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Jan 1, 1970
Use of bivalirudin for…
Abstract This study describes the use of bivalirudin in children on extracorporeal membrane oxygenation (ECMO). Pediatric patients receiving bivalirudin were compared to patients receiving heparin as the anticoagulant on ECMO...
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Jan 1, 1970
Epidemiology of Acute Kidney…
Abstract Objectives: Cardiac surgery–associated acute kidney injury occurs commonly following congenital heart surgery and is associated with adverse outcomes. This study represents the first multicenter study of neonatal cardiac surgery–associated acute..
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Jan 1, 1970
Procalcitonin and Early Postoperative…
Abstract Objectives Systemic inflammation and bacterial infections are critical occurrences after pediatric cardiac surgery. Elevated white blood cell count and C-reactive protein cannot discriminate between these two conditions in the..
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Jan 1, 1970
Timely Use of Venous-Arterial…
Abstract Supraventricular tachycardia is the most common tachyarrhythmia in pediatrics. Although postoperative junctional ectopic tachycardia (JET) is a known complication of congenital heart surgery that is typically transient, congenital JET..
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Jan 1, 1970
Native Aortic Root Thrombosis…
Abstract Background Norwood palliation for hypoplastic left heart syndrome typically results in retrograde perfusion of the native aortic root. This may predispose to native aortic root thrombosis (NART). Methods Patients..
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Jan 1, 1970
The use of thromboelastography…
Abstract “Developmental hemostasis” refers to the dynamic process of gradual hemostatic maturation. Conventional coagulation tests seem to fail to accurately depict the in vivo hemostasis, while viscoelastic tests, thromboelastography (TEG),..
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Jan 1, 1970
Neonatal Cardiopulmonary Bypass Circuit…
Abstract Blood-primed cardiopulmonary bypass circuits are frequently necessary to achieve safe support during pediatric open-heart surgery. Literature is lacking regarding suitable prime constituents or methods for achieving a physiologically appropriate..
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Jan 1, 1970
Use of Cytosorb in…
This case reports on a 66-year-old female patient who presented to hospital for elective surgical treatment of a large right-sided renal pelvic stone. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/07/CoW_30_2021_E_web_compressed.pdf"]
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Jan 1, 1970
Severe Pulmonary Hemorrhage in…
Abstract Pulmonary hemorrhage (PH) is an infrequent and potentially fatal event in term neonates. Reports of successful management of PH on extracorporeal membrane oxygenation (ECMO) are limited, given the accentuated..
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Jan 1, 1970
Successful Treatment of Suspected…
This case reports on a 62-year-old male who received a liver allograft for hepatocellular carcinoma and 2 months later was admitted with SARS-CoV-2 interstitial pneumonia. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/07/CoW_29_2021_E_web_compressed.pdf"]
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Jan 1, 1970
CytoSorb in conjunction with…
This case reports on a 52-year-old male, who was admitted to the emergency room with signs of Acute Respiratory Distress Syndrome (ARDS) and decreased urine output. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/07/CoW_28_2021_E_web_compressed.pdf"] [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/07/CoW_29_2021_E_web_compressed.pdf"]..
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Jan 1, 1970
A contemporary review of…
Abstract Improvements in the care of children with cardiomyopathy, CHDs, and acquired heart disease have led to an increased number of children surviving with advanced heart failure. In addition, the..
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Jan 1, 1970
Subzero balance – simple…
Abstract The use of cardiopulmonary bypass (CPB) can be associated with significant hemodilution, coagulopathy and a systemic inflammatory response for infants and children undergoing cardiac surgery. Intra-operative ultrafiltration has been..
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Jan 1, 1970
Efficacy of CytoSorb in…
This case reports on a 14-year-old previously healthy girl who was referred to the Pediatric Intensive Care Unit (PICU) with a suspicion of multisystem inflammatory syndrome in children (MIS-C) and..
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Jan 1, 1970
Use of extracorporeal hemoadsorption…
This case reports on a 54-year-old male patient who was treated in the medical intensive care unit at Aachen University Hospital following a generalized tonic-clonic seizure with subsequent postictal vigilance..
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Jan 1, 1970
Tetralogy of Fallot (TOF)
Tetralogy of Fallot (TOF) is a cardiac anomaly that refers to a combination of four related heart defects that commonly occur together. The four defects are: − a hole between the right..
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Jan 1, 1970
Biventricular Support Using ProtekDuo…
Abstract We report a successful pediatric bridge to transplant following application of the ProTekDuo Cannula to provide right ventricular support in a 12-year-old child with biventricular cardiomyopathy and on left..
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Jan 1, 1970
Anticoagulation and Transfusion Management…
Abstract OBJECTIVES: To compare current practices within the United States of anticoagulation management and blood transfusion in neonatal and pediatric extracorporeal membrane oxygenation patients with a 2013 international report. DESIGN: ..
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Jan 1, 1970
Dysbiosis and Intestinal Barrier…
Summary There are no data evaluating the microbiome in congenital heart disease following cardiopulmonary bypass. The authors evaluated patients with congenital heart disease undergoing cardiopulmonary bypass and noncardiac patients undergoing..
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Jan 1, 1970
Postoperative Cerebral Oxygen Saturation…
Abstract OBJECTIVES: During the early postoperative period, children with congenital heart disease can suffer from inadequate cerebral perfusion, with possible long-term neurocognitive consequences. Cerebral tissue oxygen saturation can be monitored..
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Jan 1, 1970
Stress-Induced (Takotsubo) Cardiomyopathy After…
Abstract Here, we report the case of a 55 year old male patient without significant preexisting cardiovascular disease who received a deceased donor liver transplant. Intraoperatively, the patient developed cardiogenic..
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Jan 1, 1970
Neurocognitive disorders amongst patients…
Abstract Background Amongst children with congenital heart disease (CHD), earlier age of repair improves cardiovascular outcomes. The effects of early intervention on neurodevelopment remains unclear. We assessed the association between..
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Jan 1, 1970
Understanding and managing the…
Abstract Bleeding in the perioperative period of congenital heart surgery with cardiopulmonary bypass is associated with increased morbidity and mortality both from the direct effects of haemorrhage as well as..
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Jan 1, 1970
Bivalirudin May Reduce the…
Abstract We retrospectively compared anticoagulation with heparin and bivalirudin for 32 consecutive children under 18 years old during extracorporeal membrane oxygenation (ECMO) in our pediatric cardiac intensive care unit (PCICU). Between September..
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Jan 1, 1970
Elevated Arterial–Central Venous Carbon…
Abstract Background Elevated arterial–central venous carbon dioxide partial pressure difference (AVCO2) may be an important marker to predict tissue and organ hypoperfusion in adults. We analyzed the hemodynamic data of..
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Jan 1, 1970
Hemoadsorption with CytoSorb® and…
This case reports on a 61-year-old woman with Ulrich Turner syndrome, who developed septic shock following right hemicolectomy. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/06/CoW_25_2021_E_web_compressed.pdf"]
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Jan 1, 1970
Neurological Outcome According to…
Abstract The impact of cervical cannulation on neurologic outcome has not been yet studied among children receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO) in the context of severe sepsis or septic..
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Jan 1, 1970
Transportation of Critically Ill…
Abstract Extracorporeal membrane oxygenation (ECMO) may be a life-saving procedure for patients with severe reversible pulmonary or cardiac failure or for patients in need for a bridge to transplantation. ECMO..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 63-year-old male patient (pre-existing conditions: arterial hypertension, obesity, type 2 diabetes mellitus) who was transferred from the normal ward to the medical intensive care unit..
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Jan 1, 1970
Total anomalous pulmonary venous…
Total anomalous pulmonary venous return (TAPVR) is a rare congenital malformation in which all four pulmonary veins do not connect normally to the left atrium. Instead the four pulmonary veins..
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Jan 1, 1970
Tetralogy of Fallot (TOF)…
with is a more severe form of TOF, a type of heart defect. It’s a congenital condition, which means it’s something a baby is born with. Babies who have TOF with..
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Jan 1, 1970
Tricuspid atresia with patent…
The normal pumping chambers of the heart (the ventricles) must have an inflow valve to let blood in, a good-sized pumping chamber and an outflow to allow blood to exit the..
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Jan 1, 1970
Truncus communis arteriosus Type…
In patients with a TAC only one vessel originates from the heart chambers. Generally the common vessel (truncus) overrides a ventricular septal defect. Depending on the origin of the pulmonary..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 53-year-old female patient who was transferred from the isolation ward to the Medical Intensive Care Unit due to progressive respiratory deterioration in the context of..
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Jan 1, 1970
Accidental systemic administration of…
Abstract Cardioplegia is used to induce cardiac arrest in order to facilitate cardiac surgery in patients supported by cardiopulmonary bypass. It is administered directly into the coronary vessels after the..
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Jan 1, 1970
Randomized Pilot Trial of…
Abstract Background: Due to the substantial improvement in survival among pediatric patients undergoing congenital heart surgery, reducing early and long-term morbidity is becoming the major focus of care. Blood transfusion is..
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Jan 1, 1970
Systemic Hypertension in Pediatric…
Abstract Systemic hypertension (HTN) is a recognized complication of veno-venous (VV) extracorporeal membrane oxygenation (ECMO) in children. We sought to determine the prevalence and associated features of HTN in a..
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Jan 1, 1970
Microcirculatory Changes in Pediatric…
Abstract A prospective, observational single-center study was carried out. Pediatric patients undergoing congenital heart defect surgery were evaluated before, during, and after surgery. At each time point, sublingual microcirculation and..
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Jan 1, 1970
Scavenging right atrial Bretschneider…
Abstract Objective Custodiol-HTK (Custodiol-HTK Koheler Chemie, GmbH, Bensheim, Germany) causes fluctuations in serum sodium levels, , and is associated with postoperative seizures. We investigated the influence of scavenging right atrial effluent during..
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Jan 1, 1970
Initial experience with del…
Abstract Objective: The aim of this study was to evaluate outcome measures between our standard multidose cardioplegia protocol and a del Nido cardioplegia protocol in congenital heart surgery patients. Methods:..
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Jan 1, 1970
First Harvest of Pediatric…
Abstract Objectives: A new congenital heart surgery database (CKCV) with real-time online reporting function was recently developed in Turkey. All standard international parameters were used, but Aristotle Comprehensive Complexity score..
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Jan 1, 1970
Pediatric Cardiac Surgical Patterns…
Abstract Objectives: The Japan Cardiovascular Surgery Database–Congenital section (JCVSD-Congenital) and the European Congenital Heart Surgeons Association (ECHSA) Congenital Heart Surgery Database (CHSD) share the same nomenclature. We aimed at comparing..
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Jan 1, 1970
Use of CytoSorb® as…
This case reports on a 29-year-old previously healthy male patient, who was transferred from a small hospital to the Medical Intensive Care Unit (MICU) of the University Clinical Centre of..
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Jan 1, 1970
I-PASS handover system: a…
Abstract In this issue of BMJ Quality and Safety, Jorro-Barón and colleagues report the findings of a stepped-wedge cluster randomised trial (SW-CRT) to evaluate the implementation of the I-PASS handover system among..
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Jan 1, 1970
Influence of administration of…
Abstract Objective: Mesenchymal stromal cells have important immunomodulatory and neuroprotective properties. The aim of this study was to evaluate the feasibility of mesenchymal stromal cell administration into a cardiopulmonary bypass..
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Jan 1, 1970
20-year experience with pediatric…
Abstract Background Cardiomyopathies in advanced stages and highly complex congenital heart disease may not be amenable to therapy or surgical correction thus being indicated pediatric heart transplant. In this study,..
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Jan 1, 1970
Effect of perfusate oxygenation…
Abstract Objective To examine the altitude differences in the optimal perfusate oxygenation (PpO2) in patients who underwent cardiac surgery. Methods We included children (aged 1 month to 18 years) with surgically repaired between..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 10-year-old female (37 kg), who was admitted to the inpatient pediatric department with syncope with subsequent persistent somnolence and suspected intoxication. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/05/CoW_19_2021_E_web_compressed.pdf"]
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Jan 1, 1970
Use of CytoSorb hemadsorption…
This case reports on a 55-year-old male patient who was admitted to the hospital with complaints of fever, cough, vomiting, and loss of taste from 7-8 days before admission. He..
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Jan 1, 1970
Treatment of a patient…
This case reports on a 58-year-old male patient with a medical history of ulcerative colitis, who was admitted to the Emergency Department with a body temperature up to 40°C, dry..
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Jan 1, 1970
Minimally Invasive Cardiac Surgical…
Abstract Efforts to reduce the trauma and discomfort associated with thoracic and cardiac procedures in children have a long and complex history. While much of the early focus has been..
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Jan 1, 1970
Clinical and Hematological Outcomes…
Abstract Donor shortage is a major limitation in organ transplantation. Several studies have reported that extracorporeal membrane oxygenation (ECMO)-assisted organ donation can be successfully completed without inducing warm ischemia in..
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Jan 1, 1970
Effect of cardiopulmonary bypass…
Abstract Background Little is known regarding the effect of cardiopulmonary bypass (CPB) reoxygenation on cardiac function following tetralogy of Fallot repair. We hypothesized that hyperoxic reoxygenation would be more strongly..
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Jan 1, 1970
Use of CytoSorb hemadsorption…
Abstract This case reports on a 55-year-old male patient who was admitted to the hospital with complaints of fever, cough, vomiting, and loss of taste from 7-8 days before admission...
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Jan 1, 1970
Treatment of a patient…
Abstract This case reports on a 58-year-old male patient with a medical history of ulcerative colitis, who was admitted to the Emergency Department with a body temperature up to 40°C,..
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Jan 1, 1970
Paediatric intensive care challenges…
Abstract The coronavirus disease 2019 (COVID-19) pandemic has impacted people of all ages. Although children have been largely spared from the direct impact of the pandemic and only a minority..
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Jan 1, 1970
Basics of extra corporeal…
Abstract Extra Corporeal membrane oxygenation (ECMO) is one of the most advanced forms of life support therapy in the Intensive Care Unit. It relies on the principle where an external..
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Jan 1, 1970
The Safe Addition of…
Abstract Low cardiac output syndrome and the systemic inflammatory response are consequences of the cardiac surgical perioperative course. The mechanisms responsible are multifactorial, but recent studies have shown that nitric..
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Jan 1, 1970
Timeout procedure in paediatric…
Abstract Background For over a decade, the preoperative timeout procedure has been implemented in most paediatric surgery units. However, the impact of this intervention has not been systematically studied. This..
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Jan 1, 1970
mDixon ECG-gated 3-dimensional cardiovascular…
Take Home Points: modified Dixon (mDixon) 3D cardiovascular magnetic resonance angiography (CMRA) demonstrates reduced artefact burden and better delineation of head and neck vessels as well as pulmonary veins compared..
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Jan 1, 1970
Successful treatment of neonatal…
Abstract Background Atrial flutter (AFL) is a supraventricular tachyarrhythmia. In the ECG tracing, it is marked by a fast, irregular atrial activity of 280–500 beats per minute. AFL is known..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 24-year-old female patient who was admitted to the hospital in an unresponsive state with suspected overdose of clonazepam and quetiapine, presumably 1 hour post ingestion...
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Jan 1, 1970
Palliative Care Referrals in…
Abstract OBJECTIVES: With evidence of benefits of pediatric palliative care (PPC) integration, we sought to characterize subspecialty PPC referral patterns and end of life (EOL) care in pediatric advanced heart..
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Jan 1, 1970
Minimally Invasive Extracorporeal Technologies…
Abstract Minimally invasive extracorporeal technologies (MiECT) are in great expansion in the literature and have an impact in adult cardiac surgery, however, a future challenge will be to expand MiECT..
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Jan 1, 1970
2019 updated consensus statement…
Abstract This is an updated, comprehensive and practical guideline for healthcare providers providing care to children and young adults with pulmonary hypertension (PH) and pulmonary vascular disease (PVD). Methodology included..
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Jan 1, 1970
Thromboelastography During Rewarming for…
Abstract Background Thromboelastography (TEG) predicts bleeding in pediatric patients undergoing cardiac surgery. We hypothesize that TEG parameters at rewarming correlate with post-protamine values and that rewarming TEG is associated with..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 45-year-old male patient who was hospitalized for emergency intervention due to recurrent abdominal discomfort following CT-confirmed occlusion of the superior mesenteric artery. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/04/cyto2_compressed.pdf"]
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 39-year-old patient who presented to hospital for elective surgery due to high-grade mitral valve regurgitation. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/04/cyto1_compressed.pdf"]
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Jan 1, 1970
Effect of retrograde autologous…
Abstract To evaluate the effectiveness of retrograde autologous priming (RAP) based on miniaturized cardiopulmonary bypass (CPB) circuit in children undergoing open heart surgery. We performed a retrospective analysis of all..
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Jan 1, 1970
Impact of miniaturized cardiopulmonary…
Abstract Objective: To investigate whether the miniaturized cardiopulmonary bypass (CPB) system decreased the usage of ultrafiltration (UF), and to explore whether the non-UF with miniaturized CPB strategy could get..
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Jan 1, 1970
World-first paediatric heart transplant…
Abstract Great Ormond Street Hospital (GOSH) and Royal Papworth Hospital (RPH) have collaborated to introduce a world-first paediatric heart transplant technique that has successfully expanded the donor pool and increased..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a previously fit and well 45-year-old male patient who was transferred from an ex- ternal hospital to the University Hospital St. Pölten already intubated and ventilated...
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Jan 1, 1970
Cardiac Biomarkers for Risk…
Abstract Background Children undergoing a cardiac surgical procedure are at increased risk for acute kidney injury (AKI). Novel biomarkers are needed to improve risk stratification of AKI after cardiac surgery...
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Jan 1, 1970
Anticoagulation and Transfusion Management…
Abstract Objectives: To compare current practices within the United States of anticoagulation management and blood transfusion in neonatal and pediatric extracorporeal membrane oxygenation patients with a 2013 international report. Design: ..
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Jan 1, 1970
El COVID-19 en las…
La pandemia del covid 19 ha impactado enormemente en nuestras vidas, cambiando modelos sociales, económicos y sanitarios. La información es desbordante, cambiante, instantánea, catastrófica unas veces, anecdótica otras, muchas veces..
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Jan 1, 1970
Population Pharmacokinetics and Pharmacodynamic…
Abstract OBJECTIVE This study aims to describe the population pharmacokinetics and pharmacodynamic target attainment of meropenem in critically ill children. METHODS The study involved a retrospective medical record review from..
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Jan 1, 1970
Effect of acid–base balance…
Abstract Hypoplastic left heart syndrome (HLHS) is a congenital heart defect that requires 3-stage cardiac surgical treatment and multidirectional specialist care. The condition of newborns in the first postoperative days..
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Jan 1, 1970
Remifentanil prevents increases of…
Abstract Introduction: Cardiopulmonary bypass (CPB) can cause stress response that increases levels of cytokine and catecholamine in plasma, resulting in hyperglycemia. In adults, it has been demonstrated that remifentanil infusion..
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Jan 1, 1970
The “basic” approach: a…
Abstract OBJECTIVES: Extracorporeal membrane oxygenation (ECMO) is a lifesaving but expensive therapy in terms of financial, technical and human resources. We report our experience with a ‘basic’ ECMO support model,..
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Jan 1, 1970
Topical and low-dose intravenous…
Abstract Background Coagulopathy is a major problem in surgery for cyanotic congenital heart disease. Tranexamic acid has been used both topically and systemically and plays a vital role in pediatric..
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Jan 1, 1970
Successful extracorporeal membrane oxygenation…
Abstract Abstract: Here we report two cases of extracorporeal membrane oxygenation (ECMO) support in pediatric patients following orthotopic heart transplantation due to low cardiac output and inability to separate from..
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Jan 1, 1970
Results of Extracorporeal Cardiopulmonary…
Abstract Background Survival of children experiencing cardiac arrest refractory to conventional cardiopulmonary resuscitation (CPR) is very poor. We sought to examine current era outcomes of extracorporeal CPR (ECPR) support for..
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Jan 1, 1970
Comparison of high glucose…
Abstract OBJECTIVES This study investigates the effects of high glucose content on patients undergoing cold crystalloid versus cold blood cardioplegia in terms of early clinical results, functional myocardial recovery and..
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Jan 1, 1970
The Evolution of Pediatric…
Abstract The provision of continuous renal replacement therapies (CRRT) to small children has generally required the adaptation of adult machines and modified operational characteristics. CRRT prescription for younger and smaller..
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Jan 1, 1970
Detection of coagulopathy in…
Abstract Background Each year in the UK, ≈3000 children undergo major cardiac surgery requiring cardiopulmonary bypass. Approximately 40 % of these experience excessive bleeding necessitating red cell transfusion or treatment with..
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Jan 1, 1970
Intraoperative change of lactate…
Abstract Background A change of serum lactate concentrations appeared to be useful for predicting outcomes in various acute ill settings. However, there is little information on intraoperative change of lactate..
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Jan 1, 1970
Extracorporeal Life Support Organization…
Extracorporeal membrane oxygenation (ECMO) should be considered in patients in whom a reversible pathology is known or suspected, and in whom providing ECMO poses less risks than not providing extracorporeal..
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Jan 1, 1970
Extracorporeal Membrane Oxygenation and…
Pediatric population have been affected by the Coronavirus disease 2019 (COVID-19) to a much smaller scale compared with the adult population. The severity of the disease is variable ranging from..
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Jan 1, 1970
ECMO for COVID-19 Updated…
This is an updated guideline from the Extracorporeal Life Support Organization (ELSO) for the role of extracorporeal membrane oxygenation (ECMO) for patients with severe cardiopulmonary failure due to coronavirus disease..
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Jan 1, 1970
Pediatric Extracorporeal Cardiopulmonary Resuscitation…
Why Consider ECPR for Cardiopulmonary Arrest in Children? Because Conventional CPR may not be Sufficient to Optimize Outcomes in all Pediatric Cardiopulmonary Arrests Situations Survival rates with good neurologic outcomes..
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Jan 1, 1970
Is therapeutic hypothermia during…
Abstract Introduction: The use of therapeutic hypothermia during neonatal extracorporeal membrane oxygenation (ECMO) as a neurologic protective strategy has gained interest among clinicians despite limited data. Our objective is to..
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Jan 1, 1970
Extracorporeal Membrane Oxygenation
Abstract Over the years, there have been many innovations that have come and gone. It is not often that a single idea dramatically changes how critical care is delivered. Since..
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Jan 1, 1970
Bleeding during veno-venous ECMO…
Abstract Introduction: Veno-venous extracorporeal membrane oxygenation (vvECMO) used for respiratory support is associated with clinical bleeding in at least one third of patients. Mechanisms promoting bleeding, like acquired von Willebrand..
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Jan 1, 1970
Relationship Between Transfusion of…
Abstract Objectives The authors hypothesized that transfusion of blood products in neonates and infants undergoing high-risk cardiac surgery in the absence of intraoperative coagulation monitoring increases the risk of thrombotic..
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Jan 1, 1970
Cardiopulmonary Resuscitation in Adults…
Abstract Cardiac arrest in patients on mechanical support is a new phenomenon brought about by the increased use of this therapy in patients with end-stage heart failure. This American Heart..
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Jan 1, 1970
Novel Rotational Speed Modulation…
Abstract Background Femoral venoarterial (VA-ECMO) is widely used to maintain blood flow in patients with . However, retrograde blood flow increases left ventricular (LV) afterload during femoral VA-ECMO. Additional support by means..
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Jan 1, 1970
2016 survey about temperature…
Abstract Objective: In order to assess the current status of temperature management during cardiopulmonary bypass (CPB) in China and, thereby, implement standardized management protocols, the authors carried out a national..
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Jan 1, 1970
Cerebral Microhemorrhage: A Frequent…
Abstract Objectives: This study was undertaken to estimate the incidence and burden of cerebral microhemorrhage (CM) in patients with heart disease who underwent cardiopulmonary bypass (CPB), as detected on susceptibility-weighted..
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Jan 1, 1970
Haem is associated with…
Abstract Background Haem levels are associated with thrombosis in a variety of diseases, as well as being a contributing cause of thrombotic events in animal models. Materials and Methods We..
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Jan 1, 1970
Influence of high-flow modified…
Abstract Background: Modified ultrafiltration (MUF) can be performed in infants with ventricular septal defects (VSDs) after cardiopulmonary bypass (CPB) to reduce haemodilution and its potential adverse effects. High-flow MUF might..
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Jan 1, 1970
Pediatric Extracorporeal Membrane Oxygenation
Extracorporeal life support (ECLS), commonly referred to as extracorporeal membrane oxygenation (ECMO), is a modified form of cardiopulmonary bypass. Venous blood is drained from the patient and advanced to a..
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Jan 1, 1970
Empirical Vancomycin Dosing in…
Abstract Objectives To determine the optimal vancomycin dosing regimen to achieve empirical goal trough concentrations in pediatric patients with congenital heart disease and to examine the impact of cardiopulmonary bypass..
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Jan 1, 1970
Use of CytoSorb in…
This report describes the case of a 63-year-old female patient, who was admitted to the Intensive Care Unit with the diagnosis of septic shock. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/03/caso-semana-cyto_compressed.pdf" title="caso semana cyto_compressed"]
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Jan 1, 1970
Clear fluids fasting for…
Guidelines for the management of pre-operative paediatric clear fluid fasting historically recommend a minimum of 2 h. In particular, the published guideline from European Society of Anaesthesiology (ESA) in 2011,..
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Jan 1, 1970
Silicon Micropore‐Based Parallel Plate…
Abstract Extracorporeal membrane oxygenation (ECMO) is a life support system that circulates the blood through an oxygenating system to temporarily (days to months) support heart or lung function during cardiopulmonary..
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Jan 1, 1970
Safety of nitric oxide…
Abstract We describe our experience of 30 consecutive children supported with ECMO and receiving 20 ppm of nitric oxide in the oxygenator of the ECMO circuit. Administration of nitric oxide..
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Jan 1, 1970
NGAL expression during cardiopulmonary…
Abstract Background Renal injury is a serious complication after cardiac surgery and therefore, early detection and much more prediction of postoperative kidney injury is desirable. Neutrophil gelatinase-associated lipocalin (NGAL) is..
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Jan 1, 1970
Recirculation in Extracorporeal Membrane…
We are writing to point out a simple clinical sign in a pedagogic way, about recirculation in venovenous extracorporeal membrane oxygenation (ECMO). These last years, ECMO has emerged as a..
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Jan 1, 1970
In Vitro Evaluation of…
Abstract The objective of this study was to compare the hemodynamic performances and gaseous microemboli (GME) handling ability of two pediatric oxygenators in a simulated pediatric cardiopulmonary bypass (CPB) model..
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Jan 1, 1970
Accuracy of predicted haemoglobin…
Abstract Introduction: When applying a blood-conserving approach in paediatric cardiac surgery with the aim of reducing the transfusion of homologous blood products, the decision to use blood or blood-free priming..
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Jan 1, 1970
Utility of Sonoclot in…
Abstract Objectives To assess the utility of Sonoclot in prediction of in pediatric patients undergoing cardiac surgery with for . Design Prospective, . Setting Single university hospital. Participants Eighty-seven pediatric patients undergoing cardiac surgery..
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Jan 1, 1970
Hospital-level variation in inpatient…
Abstract Objective: Pediatric extracorporeal membrane oxygenation (ECMO) varies in the way care is provided from hospital to hospital. This variability in hospital ECMO care can be represented by the variation..
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Jan 1, 1970
Extracorporeal membrane oxygenation for…
Abstract Kawasaki disease is usually a limited illness of early childhood. However, life-threatening cardiac manifestations can occur, either at acute presentation or as a consequence of coronary arterial involvement. We..
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Jan 1, 1970
Perioperative Near-Infrared Spectroscopy Monitoring…
Abstract Objectives: To evaluate the value of perioperative cerebral near-infrared spectroscopy monitoring using variability analysis in the prediction of neurodevelopmental outcomes in neonates undergoing surgery for congenital heart disease. Design: ..
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Jan 1, 1970
Central Venous to Arterial…
Abstract Objectives: Venous to arterial Co2 difference correlates with cardiac output in critically ill adults, but its utility in pediatric patients is unclear. We sought to correlate venous to arterial Co2 difference..
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Jan 1, 1970
Long-Term Survival and Causes…
Abstract Objective: Extracorporeal membrane oxygenation has been used in patients with severe circulatory or respiratory failure since the 1970s, but the knowledge on long-term survival in this group is scarce...
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Jan 1, 1970
Oncotic pressure and paediatric…
Abstract Objectives: Colloid osmotic pressure (COP) is a major determinant of fluid shift in paediatric patients undergoing corrective surgery for congenital heart disease (CHD) using cardiopulmonary bypass (CPB). However, very..
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Jan 1, 1970
Avoiding use of total…
Abstract Deep hypothermic circulatory arrest (DHCA) technique has been an important armamentarium in the correction of congenital heart diseases. There have been many controversies and concerns associated with DHCA, particularly..
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Jan 1, 1970
Systemic inflammatory response syndrome…
Abstract BACKGROUND Systemic inflammatory response syndrome (SIRS) is frequent after cardiac surgery, but data on its incidence and perioperative risk factors are scarce for children with congenital heart disease. METHODS..
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Jan 1, 1970
Mechanical Circulatory Support Devices…
Abstract The use of mechanical circulatory support (MCS) devices is a viable therapeutic treatment option for patients with congestive heart failure. Ventricular assist devices, cavopulmonary assist devices, and total artificial..
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Jan 1, 1970
The Impact and Statistical…
Abstract Background: We sought to determine whether the introduction of a new anticoagulation protocol improved the frequency with which target anticoagulation parameters were met in children supported with extracorporeal membrane..
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Jan 1, 1970
Insertion of the Avalon…
Abstract Cardiopulmonary AG, Rastatt, Germany) can be effective in patients requiring venovenous extracorporeal membrane oxygenation (VV-ECMO) for adult respiratory distress syndrome (ARDS). Proper placement of the cannula is important in..
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Jan 1, 1970
Nitric oxide administration during…
Abstract Purpose Cardiopulmonary bypass induces an ischaemia–reperfusion injury and systemic inflammatory response, which contributes to low cardiac output syndrome following cardiac surgery. Exogenous nitric oxide during cardiopulmonary bypass has shown..
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Jan 1, 1970
Protamine reduces whole blood…
Abstract Objectives: Platelet dysfunction is an important cause of postoperative bleeding after cardiac surgery. Protamine is routinely used for reversal of heparin after cardiopulmonary bypass (CBP), but may affect platelet..
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Jan 1, 1970
Outcome Comparison in Children…
Abstract Purpose: To compare characteristics and outcome in children undergoing extracorporeal life support initiated in an extracorporeal life support center or at the patient’s bedside in a local hospital, by..
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Jan 1, 1970
2020 ESC Guidelines for…
1 Preamble Guidelines summarize and evaluate available evidence with the aim of assisting health professionals in proposing the best management strategies for an individual patient with a given condition. Guidelines..
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Jan 1, 1970
2010. ESC Guidelines for…
The Task Force on the Management of Grown-up Congenital Heart Disease of the European Society of Cardiology (ESC) Endorsed by the Association for European Paediatric Cardiology (AEPC) Guidelines summarize and..
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Jan 1, 1970
Extracorporeal Membrane Oxygenation for…
Abstract Objectives: Recent analyses show higher mortality at low-volume centers providing extracorporeal membrane oxygenation. We sought to identify factors associated with center volume and mortality to explain survival differences and..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 36-year-old female patient (relevant previous diseases: hereditary sensorimotor polyneuropathy with initial diagnosis in the ‘90s), who presented for a liver consultation. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/03/caso-cyto_compressed.pdf" title="caso cyto_compressed"]
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Jan 1, 1970
Clinical equivalency of cardiopulmonary…
Abstract Objective Pediatric surgery for congenital tracheal stenosis continues to be a therapeutic challenge, and it often requires cardiopulmonary bypass (CPB) or extracorporeal membrane oxygenation (ECMO) for intra-operative extracorporeal cardiorespiratory..
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Jan 1, 1970
Bivalirudin for Alternative Anticoagulation…
Abstract Background: Extracorporeal membrane oxygenation (ECMO) offers therapeutic options in refractory respiratory and/or cardiac failure. Systemic anticoagulation with heparin is routinely administered. However, in patients with heparin-induced thrombocytopenia or heparin..
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Jan 1, 1970
Vitamin D Status After…
Abstract Deficiency in 25-hydroxyvitamin D (25OHD) is associated with increased morbidity and mortality in the critically ill. Children who underwent surgery for congenital heart disease under cardiopulmonary bypass (CPB) are..
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Jan 1, 1970
Brain in Congenital Heart…
Abstract The number of patients surviving with congenital heart disease (CHD) has soared over the last 3 decades. Adults constitute the fastest-growing segment of the CHD population, now outnumbering children...
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Jan 1, 1970
Intraoperative Red Blood Cell…
Abstract BACKGROUND: Red blood cell (RBC) transfusion is common during infant cardiac surgery. A previous report of pediatric heart transplant recipients showed that increased RBC transfusion volume was independently associated..
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Jan 1, 1970
Thromboelastography—does it impact blood…
Abstract Background The administration of blood products during pediatric cardiac surgery is common. We sought to determine if thromboelastography (TEG) is a cost-effective tool to reduce blood product transfusion in..
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Jan 1, 1970
Contrast media exposure in…
Abstract Background Recently, there has been an interest in the temporal relationship between contrast exposure (CM) and cardiac surgery suggesting that a “double hit” on the kidney function in close..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 52-year-old female patient who was hospitalized via the ambulance service post resuscitation in the context of drug intoxication with metoprolol, benzodiazepine and hydromorphine, as it..
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Jan 1, 1970
Optimizing Thrombin Generation with…
Abstract BACKGROUND: Bleeding is a serious complication after pediatric cardiopulmonary bypass (CPB) that is associated with an increase in perioperative morbidity and mortality. Four-factor prothrombin complex concentrates (4F-PCCs) have been..
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Jan 1, 1970
The Kidney in Critical…
Abstract The field of cardiac intensive care continues to advance in tandem with congenital heart surgery. The focus of intensive care unit care has now shifted to that of morbidity..
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Jan 1, 1970
“Just-In-Time” Simulation Training Using…
Abstract Background: High-fidelity simulation using patient-specific three-dimensional (3D) models may be effective in facilitating pediatric cardiac intensive care unit (PCICU) provider training for clinical management of congenital cardiac surgery patients...
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Jan 1, 1970
Postoperative Abdominal NIRS Values…
Abstract Background: The development of low cardiac output syndrome (LCOS) after cardiopulmonary bypass (CPB) occurs in up to 25% of neonates and is associated with increased morbidity. Invasive cardiac output..
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Jan 1, 1970
Advancing Cardiac Critical Care:…
Abstract The evolution and development of pediatric cardiac critical care as a distinct subspecialty have occurred rapidly over the past 20 years. As the field has grown, models for education,..
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Jan 1, 1970
Poly-2-methoxyethylacrylate-coated cardiopulmonary bypass circuit…
Abstract Several coating techniques for extracorporeal circulation have been developed to reduce the systemic inflammatory response during cardiopulmonary bypass (CPB). We compared the clinical effectiveness and biocompatibility of poly-2-methoxyethylacrylate (PMEA)-..
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Jan 1, 1970
Prediction of the impact…
Abstract Although venoarterial extracorporeal membrane oxygenation (ECMO) was developed to rescue patients with cardiogenic shock, the impact of ECMO on hemodynamics is often unpredictable and can lead to hemodynamic collapse...
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Jan 1, 1970
Antithrombin III for critically…
Abstract Background Critical illness is associated with uncontrolled inflammation and vascular damage which can result in multiple organ failure and death. Antithrombin III (AT III) is an anticoagulant with anti‐inflammatory..
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Jan 1, 1970
Transparency and Public Reporting…
Abstract Health care is embarking on a new era of increased transparency. In January 2015, the Society of Thoracic Surgeons (STS) began to publicly report outcomes of pediatric and congenital..
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Jan 1, 1970
Changes in thrombin generation…
Abstract Impaired haemostasis has been reported in children with congenital heart disease undergoing cardiopulmonary bypass. As thrombin generation encompasses all phases of the coagulation process, this analysis might provide the best assessment..
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Jan 1, 1970
Nadir oxygen delivery during…
Abstract Background Cardiac surgery associated acute kidney injury (CS-AKI) is common in infants and associates with negative outcomes. Nadir indexed oxygen delivery (DO 2i) during cardiopulmonary bypass (CPB) is associated with..
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Jan 1, 1970
Takotsubo Cardiomyopathy Following Cardiac…
Abstract Background Coronavirus disease 2019 (COVID-19) remains a worldwide pandemic with a high mortality rate among patients requiring mechanical ventilation. The limited data that exist regarding the utility of extracorporeal..
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Jan 1, 1970
Bridging the Gap Between…
Abstract Importance Extracorporeal membrane oxygenation (ECMO) is a form of advanced life support that may be used in children with refractory respiratory or cardiac failure. While it is required infrequently, in..
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Jan 1, 1970
Bridging the Gap Between…
Abstract Importance Extracorporeal membrane oxygenation (ECMO) is a form of advanced life support that may be used in children with refractory respiratory or cardiac failure. While it is required infrequently, in..
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Jan 1, 1970
Bedside Allogeneic Erythrocyte Washing…
Abstract Background Removal of cytokines, chemokines, and microvesicles from the supernatant of allogeneic erythrocytes may help mitigate adverse transfusion reactions. Blood bank–based washing procedures present logistical difficulties; therefore, we tested..
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Jan 1, 1970
Factors associated with acute…
Abstract Background Cardiac surgery with cardiopulmonary bypass (CPB) is known to contribute towards the incidence of acute kidney injury (AKI) and peri-operative morbidity and mortality. There are several patient, anaesthetic..
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Jan 1, 1970
Cardiovascular Consequences and Considerations…
THE CURRENT pandemic owing to coronavirus disease 2019 (COVID-19) has been associated in about 10% to 15% of cases with severe clinical presentations that require admission to hospital. In the..
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Jan 1, 1970
Extracorporeal Membrane Oxygenation Support…
Abstract Background Coronavirus disease 2019 (COVID-19) remains a worldwide pandemic with a high mortality rate among patients requiring mechanical ventilation. The limited data that exist regarding the utility of extracorporeal..
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Jan 1, 1970
Bridging the Gap Between…
Abstract Importance Extracorporeal membrane oxygenation (ECMO) is a form of advanced life support that may be used in children with refractory respiratory or cardiac failure. While it is required infrequently, in..
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Jan 1, 1970
DUKE HEALTH PERFORMS WORLD’S…
A team at Duke Health has performed what is believed to be the world’s first partial heart transplant, with the living arteries and valves from a freshly donated heart fused..
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Jan 1, 1970
Continuous Metabolic Monitoring in…
Abstract Cardiopulmonary bypass (CPB) in infants is associated with morbidity due to systemic inflammatory response syndrome (SIRS). Strategies to mitigate SIRS include management of perfusion temperature, hemodilution, circuit miniaturization, and..
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Jan 1, 1970
Current status of brain…
Abstract The long-term neurodevelopmental outcome has been a great concern for cardiac surgeons although it is still unclear. There are some risks regarding the neurological and neuropsychological deficits before, during..
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Jan 1, 1970
del Nido cardioplegia in…
Abstract The convenience offered by a single-dose cardioplegia strategy is the avoidance of interruption of the flow of surgery and, more importantly, a significant reduction in the cross-clamp time. del..
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Jan 1, 1970
Challenges with heparin-based anticoagulation…
Abstract Background is one of the main natural inhibitors. It is potentiated by heparin, and may be a key component of heparin response, particularly in infants aged <1 year. We sought to..
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Jan 1, 1970
Are We Overdiagnosing Acute…
Abstract Background: The use of two diagnostic criteria in the current literature has led to some degree of ambiguity in the precise diagnosis of acute kidney injury in pediatric patients..
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Jan 1, 1970
Outcome after aortic valve…
Abstract Objective Despite an increasing interest in pediatric repair, in children may be unavoidable. The evidence on outcome after pediatric aortic valve replacement is limited and usually reported in small case series...
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Jan 1, 1970
Central extracorporeal membrane oxygenation…
Abstract Objective: To demonstrate positive outcome, to achieve higher flow rates, and to reverse shock more quickly by implementing central extracorporeal membrane oxygenation (ECMO) in children with refractory septic shock. Children..
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Jan 1, 1970
Extracorporeal Membrane Oxygenation for…
Abstract Because of a severe dysregulation of the host response to infection, septic shock may induce a profound imbalance between oxygen consumption and delivery, which in some cases may be..
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Jan 1, 1970
The Hemovent Oxygenator: A…
Abstract Extracorporeal membrane oxygenation (ECMO) and extracorporeal carbon dioxide removal (ECCO2R) provide respiratory support aimed at gaining time to allow patient’s recovery from hypoxemic and/or hypercapnic respiratory failure, respectively. However, in..
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Jan 1, 1970
Successful Antithrombin Administration in…
Abstract Case Report A 72-year-old man with a tachycardiomyopathy, atrium flutter, and atrial fibrillation underwent an elective radiofrequency ablation procedure. In addition to 5 mg of apixaban twice daily, his..
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Jan 1, 1970
Observational study of thrombosis…
Abstract Introduction: COVID-19 has been associated with increased risk of thrombosis, heparin resistance and coagulopathy in critically ill patients admitted to intensive care. We report the incidence of thrombotic and..
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Jan 1, 1970
Hypofibrinogenemia can be estimated…
Abstract Objective Aortic surgery often causes massive bleeding due to hypofibrinogenemia. Predicting hypofibrinogenemia is useful for developing a hemostasis strategy, including preparing for blood transfusion. We made a formula for..
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Jan 1, 1970
Hemoadsorption to treat severe…
This case reports on a 27-year-old woman (body weight 45 kgs), who was admitted to the Emergency Department of a peripheral hospital in Brussels due to intoxication of unknown origin...
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Jan 1, 1970
Mechanisms of oxidative stress…
Abstract We investigated MBL2 and MASP2 genotypes, serum MBL (mannose-binding lectin) levels and activities of its complexes with associated serine Cold heart protection via cardioplegia administration, limits the amount of oxygen demand. Systemic normothermia..
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Jan 1, 1970
Mannose-binding lectin (MBL) insufficiency…
Abstract We investigated MBL2 and MASP2 genotypes, serum MBL (mannose-binding lectin) levels and activities of its complexes with associated serine proteases (MASP-1, MASP -2), in relation to complications following cardiac surgery in 195 children...
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Jan 1, 1970
Effects of modified ultrafiltration…
Abstract Background: This meta-analysis was performed to review the effects of the addition of modified ultrafiltration (MUF) and conventional ultrafiltration (CUF) to CUF alone on postoperative hemoglobin, surgical and ultrafiltration..
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Jan 1, 1970
Modified ultrafiltration reduces postoperative…
Abstract OBJECTIVES Cardiopulmonary bypass in cardiac surgery has been associated with several deleterious effects including haemodilution and systemic inflammation. Modified ultrafiltration (MUF) has been well established in paediatric cardiac surgery..
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Jan 1, 1970
Terapia de reemplazo renal…
Terapia de reemplazo renal con CytoSorb – Post-filtro Antes de la conexión de CytoSorb, el sistema de línea de entrada debe cebarse previamente con solución salina isotónica estéril sin aire...
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Jan 1, 1970
RRT with CytoSorb –…
RRT with CytoSorb – Post Filter Before connecting CytoSorb the supply tubing system must be airlessly primed with sterile isotonic saline solution. • Under no circumstances should air enter the..
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Jan 1, 1970
Terapia de reemplazo renal…
Terapia de reemplazo renal con CytoSorb – Pre-filtro Antes de la conexión de CytoSorb, el sistema de línea de entrada debe cebarse previamente con solución salina isotónica estéril sin..
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Jan 1, 1970
RRT with CytoSorb –…
RRT with CytoSorb – Pre Filter Before connecting CytoSorb the supply tubing system must be airlessly primed with sterile isotonic saline solution. • Under no circumstances should air enter the..
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Jan 1, 1970
Exchange of the CytoSorb…
Exchange of the CytoSorb Adsorber Before connecting CytoSorb the supply tubing system must be airlessly primed with sterile isotonic saline solution. • Under no circumstances should air enter the CytoSorb..
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Jan 1, 1970
Hemoperfusion with CytoSorb (video)
Hemoperfusión with CytoSorb Before connecting CytoSorb the supply tubing system must be airlessly primed with sterile isotonic saline solution. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Hemoperfusion-with-CytoSorb-Quick-Setup-Guide_compressed.pdf" title="Hemoperfusion with CytoSorb Quick Setup Guide_compressed"] https://youtu.be/cIzKmwSIGT8
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Jan 1, 1970
ECMO with CytoSorb (video)
ECMO with CytoSorb The preparation and use of CytoSorb must always be carried out under hygienic conditions. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/ECMO-with-CytoSorb-Quick-Setup-Guide_compressed.pdf" title="ECMO with CytoSorb Quick Setup Guide_compressed"] https://youtu.be/Wm8AU29Uc3Y
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Jan 1, 1970
Cambio del CytoSorb (video)
Cambio del CytoSorb Antes de la conexión de CytoSorb, el sistema de línea de entrada debe cebarse previamente con solución salina isotónica estéril sin aire. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Cambio-del-CytoSorb-Guía-rápida-de-configuración_compressed.pdf" title="Cambio del CytoSorb..
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Jan 1, 1970
Hemoperfusión con CytoSorb (video)
Hemoperfusión con CytoSorb Antes de la conexión de CytoSorb, el sistema de tubos de entrada debe cebarse previamente con solución salina isotónica estéril sin aire. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Hemoperfusión-con-CytoSorb-Guía-rápida-de-configuración_compressed.pdf" title="Hemoperfusión con..
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Jan 1, 1970
ECMO con CytoSorb (video)
ECMO con CytoSorbECMO con CytoSorb El tratamiento con CytoSorb se aplicó de forma prospectiva y se analizó de forma retrospectiva en el grupo de control, en los pacientes con..
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Jan 1, 1970
CPB with CytoSorb –…
CPB with CytoSorb – Intraoperative Use (video). Setup the cardiopulmonary bypass machine completely according to the operating instructions of the device manufacturer (including priming). [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/CPB-with-CytoSorb-–-Intraoperative-Use-Quick-Setup-Guide_compressed.pdf" title="CPB with CytoSorb –..
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Jan 1, 1970
CEC con CytoSorb –…
CEC con CytoSorb - Uso intraoperatorio Preparar por completo la máquina cardiopulmonar según las instrucciones de uso del fabricante (incluyendo el cebado). [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/CEC-con-CytoSorb-Uso-intraoperatorio-Guía-rápida-de-configuración_compressed.pdf" title="CEC con CytoSorb – Uso intraoperatorio..
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Jan 1, 1970
An Adjusted Calculation Model…
Abstract Background Heparin dosage for anticoagulation during cardiopulmonary bypass (CPB) is commonly calculated based on the patient's body weight. The protamine–heparin ratio used for heparin reversal varies widely among institutions..
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Jan 1, 1970
Association of Hospital-Level Volume…
Abstract Rationale: Recent pediatric studies suggest a survival benefit exists for higher-volume extracorporeal membrane oxygenation (ECMO) centers. Objectives: To determine if higher annual ECMO patient volume is associated with lower..
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Jan 1, 1970
Use of CytoSorb in…
This case study reports on a 56-year-old female patient who presented at the Cardiac Center Aarau for elective mitral valve reconstruction/replacement and left atrial appendage occlusion, after she suffered cardiac..
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Jan 1, 1970
Use of CytoSorb in…
This case study reports on a 58-year-old female patient (known pre-existing conditions: very severe COPD (Gold stage IV), encapsulated pleural effusion with suspicion of empyema after left lung volume reduction..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 7-month-old male pediatric patient (known pre-existing conditions: trisomy 21 (also known as Downs syndrome), aortic isthmus stenosis, atrioventricular septal defect (AVSD) Rastelli type C), who..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 48-year-old male patient who was transferred by air ambulance from a Caribbean island to Hospital Pacifica Salud in Panama due to a stroke, altered consciousness,..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 13-year-old male patient who presented to hospital with fever (38.9°), reduced general condition, vomiting and pain in his limbs. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Use-of-CytoSorb-in-a-pediatric-patient-with-severe-rhabdomyolysis-in-the-context-of-a-SARS-CoV-2-infection_compressed.pdf" title="Use of CytoSorb..
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Jan 1, 1970
Use of CytoSorb in…
This report describes the case of a 59-year-old patient who was transferred from a peripheral hospital for emergency surgery for a type A aortic dissection with paraparesis of the legs,..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 31-year-old male patient with no significant medical history, who was hospitalized following several days of non-quantified fever associated with odynophagia. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Use-of-CytoSorb-in-a-patient-with-severe-COVID-19_compressed.pdf" title="Use of..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 79-year-old female patient who presented to the hospital for elective surgery due to severe mitral valve and tricuspid valve insufficiency. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Use-of-CytoSorb-in-a-patient-with-severe-ARDS-and-septic-shock-after-mitral-valve-and-tricuspid-valve-reconstruction_compressed.pdf" title="Use of..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 2-year-old male patient (weight 12 kg), who was admitted to the children‘s outpatient department with anuria, bloody diarrhea, anemia and severe edema (anasarca). [pdf-embedder..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 76-year-old male patient, who was admitted to the emergency department two weeks after an elective and initially complication-free pancreas resection with acute abdomen, signs of..
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Jan 1, 1970
Use of CytoSorb in…
This case study reports on a 59-year-old patient who presented with dyspnea and weight gain of 12 kg at a peripheral hospital. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Use-of-CytoSorb-in-a-patient-with-mitral-valve-dysfunction-atypical-pneumonia-and-mixed-cardiogenic-and-septic-shock_compressed.pdf" title="Use of CytoSorb in a..
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Jan 1, 1970
Ticagrelor and Rivaroxaban Elimination…
This case reports on a 58-year-old male patient who was admitted to the South Munich Surgical Clinic for urgent coronary artery bypass surgery. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Ticagrelor-and-Rivaroxaban-Elimination-With-CytoSorb-Adsorber-Before-Urgent-Off-Pump-Coronary-Bypass-_compressed.pdf" title="Ticagrelor and Rivaroxaban Elimination..
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Jan 1, 1970
Use of CytoSorb in…
This case reports on a 23-year-old male patient, who was admitted to the hospital with complaints of dyspnea associated with tiredness, dizziness and chest discomfort. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Use-of-CytoSorb-in-a-patient-undergoing-orthotopic-heart-transplant-surgery-_compressed.pdf" title="Use of..
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Jan 1, 1970
Reducir el riesgo de…
El uso intraoperatorio de CytoSorb en pacientes sometidos a tratamiento con ticagrelor o rivaroxaban que tienen que someterse a una cirugía de emergencia a corazón abierto es un método seguro..
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Jan 1, 1970
Purificación sanguínea inteligente para…
Con el uso de Cytosorb los datos clínicos actuales apuntan claramente a una estabilización rápida de la hemodinamia y las funciones orgánicas de los pacientes de cuidados intensivos con síndrome..
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Jan 1, 1970
Reduce peri-operative bleeding risk…
The intraoperative use of the CytoSorb hemoadsorption in patients with ticagrelor or rivaroxaban treatment undergoing emergency open-heart operations is a safe and effective method to reduce bleeding complications and to..
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Jan 1, 1970
Reduce bleeding complications in…
Ticagrelor is a platelet aggregation inhibitor and is recommended in the current European Guidelines for the treatment of acute coronary syndrome and prevention of stent thrombosis. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Reduce-bleeding-complications-in-patients-on-ticagrelor_compressed.pdf" title="Reduce..
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Jan 1, 1970
Reducción de complicaciones hemorrágicas…
El ticagrelor es un inhibidor de la agregación plaquetaria y se recomienda en las directrices europeas para el tratamiento del síndrome coronario agudo y para la profilaxis de la trombosis..
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Jan 1, 1970
Perioperative use of the…
This case study reports on a 69-year-old female patient (pre-existing medical conditions: chronic heart failure NYHA III, Type 2 diabetes mellitus, multiple myeloma, chronic kidney disease stage 3), who was..
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Jan 1, 1970
Intraoperative extracorporeal cytokine adsorption…
The following case study reports on a 13-year-old pediatric patient (body weight 45 kg) who was admitted to our hospital due to a deterioration in his clinical condition, after he..
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Jan 1, 1970
Intra- and postoperative use…
This case reports on a 49-year-old previously healthy female patient, who presented to the Accident and Emergency Department of a peripheral hospital with complaints of breathlessness and fever for one..
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Jan 1, 1970
CytoSorb Therapy Intelligent Blood…
In these patients there is a high chance of success (shock reversal) possibly translating to survival benefits when the adsorber treatment is started in good time. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/CytoSorb-Therapy_compressed.pdf" title="CytoSorb..
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Jan 1, 1970
CytoSorb Therapy Manage cytokine…
Limited treatment options are currently available for critically-ill COVID-19 ICU patients who may experience mortality rates up to 50%. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/CytoSorb-Therapy-Manage-cytokine-storm-in-patients-with-COVID-19_compressed.pdf" title="CytoSorb Therapy Manage cytokine storm in patients with..
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Jan 1, 1970
CytoSorb Therapy enhanced ECMO
CytoSorb Therapy was prospectively applied and retrospectively analyzed to the control group, in patients with pneumogenic sepsis and ARDS until shock reversal was achieved [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/CytoSorb-Therapy-enhanced-ECMO_compressed.pdf" title="CytoSorb Therapy enhanced..
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Jan 1, 1970
CytoSorb in the management…
This case reports on a 58-year-old male was hospitalized with a 2-day history of chest pain and dyspnea on exertion (New York Heart Association Class III). [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/CytoSorb-in-the-management-of-severe-septic-shock-after-coronary-artery-bypass-graft-surgery_compressed.pdf" title="CytoSorb..
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Jan 1, 1970
Cytosorb for Management of…
This case reports on a 6-year-old, previously healthy girl who presented to the hospital with a febrile illness and profound pain in her lower extremities. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Cytosorb-for-Management-of-Acute-Kidney-Injury-due-to-Rhabdomyolysis-in-a-Child_compressed.pdf" title="Cytosorb for..
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Jan 1, 1970
Terapia CytoSorb: Manejo de…
Actualmente se dispone de opciones de tratamiento limitadas para pacientes graves de COVID-19 en UCI, pudiendo alcanzar tasas de mortalidad de hasta el 50 %. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/cytosorb-covid19_compressed.pdf" title="cytosorb covid19_compressed"]
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Jan 1, 1970
CytoSorb complementa la terapia…
El tratamiento con CytoSorb se aplicó de forma prospectiva y se analizó de forma retrospectiva en el grupo de control, en los pacientes con sepsis de orígen pulmonar y SDRA..
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Jan 1, 1970
Neonatal and Pediatric General…
Abstract This review wants to give an overview to most of the controversial fields in the clinical therapeutic assistance in neonatal and pediatric general and cardiothoracic surgery in anaesthesia and..
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Jan 1, 1970
Extracorporeal Life Support
Abstract This is a review of the University of Michigan experience with extracorporeal life support (ECLS) also known as extracorporeal membrane oxygenation (ECMO). Two thousand patients were managed with ECMO..
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Jan 1, 1970
The Efficacy, Safety and…
Abstract Objective: Intra-operative cell salvage (CS) was reported to be ineffective, safe and not cost-effective in low-bleeding-risk cardiac surgery with cardiopulmonary bypass (CPB), but studies in high-bleeding-risk cardiac surgery are limited...
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Jan 1, 1970
Post-Operative Bleeding Risk Stratification…
Abstract The prediction of bleeding risk in cardiopulmonary bypass (CPB) patients plays a vital role in their postoperative management. Therefore, an artificial neural network (ANN) to analyze intra-operative laboratory data..
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Jan 1, 1970
Hemolytic characteristics of three…
Abstract Introduction: We have been developing a closed-circuit cardiopulmonary bypass (CPB) system (“Dihead CPB”) for application during coronary artery bypass grafting (CABG) and valve surgery. To strive for minimal hemolysis..
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Jan 1, 1970
Developments in Pediatric Ventricular…
Abstract Mechanical support devices have revolutionized the management of circulatory failure. This has been met by a dramatic increase in ventricular assist device (VAD) utilization in children over the last..
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Jan 1, 1970
Establishing an ECMO program…
Abstract Aim: The ECMO (extracorporeal membrane oxygenation) Program at the American University of Beirut Medical Center was established in November 2015 as the first program serving adult and pediatric population..
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Jan 1, 1970
Aprotinin versus tranexamic acid…
Abstract OBJECTIVES: The upcoming release of aprotinin in paediatric cardiac surgery prompted a re-evaluation of its use in comparison to tranexamic acid (TXA) focusing on their effect on exposure to..
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Jan 1, 1970
Hemolytic characteristics of three…
Abstract Introduction: We have been developing a closed-circuit cardiopulmonary bypass (CPB) system (“Dihead CPB”) for application during coronary artery bypass grafting (CABG) and valve surgery. To strive for minimal hemolysis..
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Jan 1, 1970
Anticoagulation during ECMO in…
Abstract (ECMO) is a form of (ECLS) which is used frequently in the paediatric and neonatal setting to support either the pulmonary, or both the pulmonary and . Management of ECMO requires..
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Jan 1, 1970
Correlation of cardiopulmonary bypass…
Abstract Objectives Prolonged (CPB) is recognized as a risk factor for (ARF), but the dose effect of time on bypass is unknown. We therefore examined the risk of ARF associated with increasing..
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Jan 1, 1970
Acute kidney injury and…
Abstract Acute kidney injury is a common and serious complication after congenital heart surgery, particularly among infants. This comorbidity has been independently associated with adverse outcomes including an increase in..
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Jan 1, 1970
Extracorporeal Cardiopulmonary Resuscitation: One-Year…
Abstract Objective: To describe neurobehavioral outcomes and investigate factors associated with survival and survival with good neurobehavioral outcome 1 year after in-hospital cardiac arrest for children who received extracorporeal cardiopulmonary..
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Jan 1, 1970
Pediatric out-of-hospital cardiac arrest:…
Abstract Aim Although recent (CA) trials found no benefits of versus normothermia , preclinical models suggest earlier timing of hypothermia improves efficacy. This study investigated whether shorter time to goal temperature was associated with..
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Jan 1, 1970
Postoperative Acute Kidney Injury…
Abstract Background There is an increasing number of young adults living with (CHD). The goal of this study was to ascertain the frequency of (AKI) as well as the risk factors and..
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Jan 1, 1970
Trends and Updates on…
Abstract Perfusion strategies for have direct consequences on pediatric cardiac surgery outcomes. However, inconsistent study results and a lack of uniform evidence-based guidelines for pediatric cardiopulmonary bypass management have led to..
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Jan 1, 1970
Pharmacokinetics of cefazolin delivery…
Abstract Objectives Our aim was to describe the pharmacokinetics of cefazolin in paediatric patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) who received cefazolin for peri-operative surgical prophylaxis in addition..
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Jan 1, 1970
Pediatric Transfusion Algorithms: Coming…
Abstract Pediatric cardiac surgical patients are at particular risk for post-cardiopulmonary bypass hemorrhage. Moreover, both the incidence and volume of have been associated with increased morbidity in pediatric cardiac patients. Transfusion..
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Jan 1, 1970
Blood Lactate as a…
Abstract The objective of this study is to establish reliable markers for mortality in children with refractory cardiogenic shock who underwent extracorporeal membrane oxygenation. A retrospective observational cohort study was..
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Jan 1, 1970
Cardioplegia in paediatric cardiac…
OBJECTIVES Cardioplegia is the primary method for myocardial protection during cardiac surgery. We conducted a systematic review of randomized controlled trials of cardioplegia in children to evaluate the current evidence..
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Jan 1, 1970
Hemolytic characteristics of three…
Abstract Introduction: We have been developing a closed-circuit cardiopulmonary bypass (CPB) system (“Dihead CPB”) for application during coronary artery bypass grafting (CABG) and valve surgery. To strive for minimal hemolysis..
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Jan 1, 1970
Extracorporeal cardiopulmonary resuscitation for…
Abstract Aim To assess the use of (ECPR), compared with manual or mechanical cardiopulmonary resuscitation (CPR), for (OHCA) and in-hospital cardiac arrest (IHCA) in adults and children. Methods The PRISMA guidelines were..
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Jan 1, 1970
Acquired von Willebrand syndrome…
Abstract Background Bleeding contributes to the high mortality of venovenous membrane oxygenation (vvECMO). The development of acquired von Willebrand syndrome (AVWS) has been identified as relevant pathology during ECMO. This study..
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Jan 1, 1970
Cerebral Hypoxia Caused by…
CURRENTLY, MINIMALLY INVASIVE cardiac surgery (MICS) is very popular. In most cases, cardiopulmonary bypass (CPB) is used with femoral arterial cannulation, and the whole body is perfused in a retrograde..
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Jan 1, 1970
Conventional or minimized cardiopulmonary…
Abstract The use of minimized cardiopulmonary bypass support to reduce the side effects of extracorporeal circulation is still contradictorily discussed. This study compares perfusion operated by conventional (CCPB) and minimized..
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Jan 1, 1970
Comparison of the Coagulation…
Abstract OctaplasLG is indicated for use in patients undergoing cardiac surgery who require replacement of multiple clotting factors. The use of OctaplasLG over single-donor fresh frozen plasma (FFP) may have..
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Jan 1, 1970
Fluid Management With Peritoneal…
Abstract Children who undergo cardiac surgery with cardiopulmonary bypass are a unique population at high risk for postoperative acute kidney injury (AKI) and fluid overload. Fluid management is important in..
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Jan 1, 1970
Patient Blood Management in…
Abstract Efforts to reduce blood product transfusions and adopt blood conservation strategies for infants and children undergoing cardiac surgical procedures are ongoing. Children typically receive red blood cell and coagulant..
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Jan 1, 1970
National Benchmarks for Proportions…
Abstract Background To determine national benchmarks and assess variability across centers, The Society of Thoracic Surgeons Congenital Heart Surgery Database was analyzed to document proportions of patients receiving intraoperative transfusion..
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Jan 1, 1970
Anatomy of the Functionally…
Abstract The world of pediatric cardiac surgery and cardiac surgery as a whole lost one of the great pioneers with the passing, at the beginning of 2018, of Francis Fontan...
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Jan 1, 1970
Thoracic Bleeding Complications in…
Abstract Background Patients with respiratory failure are treated more frequently with venovenous (vv-ECMO). These patients are at risk for bleeding due to complex multifactorial resulting from the . Methods A retrospective analysis was conducted..
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Jan 1, 1970
Cardioplegia practice in paediatric…
Abstract Introduction: Many techniques are available for cardioplegic arrest in children, but there is a lack of late phase clinical trials to guide practice. We surveyed paediatric cardiac surgeons and..
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Jan 1, 1970
Pediatric extracorporeal membrane oxygenation…
Abstract Extracorporeal membrane oxygenation (ECMO) is a life-saving treatment for pediatric patients with respiratory and/or cardiac failure. The ECMO circuit oxygenates and sometimes pumps the blood, effectively replacing lung and/or..
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Jan 1, 1970
Albumin 5% Versus Crystalloids…
Abstract Objectives: To determine the clinical benefit of using colloids versus crystalloids for volume resuscitation in children admitted after cardiac surgery. Design: Retrospective pre-/postintervention cohort study. Setting: Stollery Children’s Hospital..
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Jan 1, 1970
Feasibility of autologous intraoperative…
Abstract Introduction Allogeneic blood product transfusion is common in pediatric patients undergoing cardiopulmonary bypass although it is associated with an increased risk for adverse events. Furthermore, numerous donor exposures may..
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Jan 1, 1970
The Starling Relationship and…
Abstract The use of veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) to support patients with acute heart failure has been associated with ventricular distension and pulmonary edema, the mechanism of which..
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Jan 1, 1970
Cardiac Surgery–Associated Kidney Injury…
Abstract Objectives: Cardiac surgery–associated acute kidney injury is common in children and associates with negative outcomes. Novel interventions to reduce cardiac surgery–associated acute kidney injury require knowledge of its pathophysiology...
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Jan 1, 1970
Continuous cytokine haemoadsorption incorporated…
Abstract Introduction: The acute surgical treatment of infective endocarditis (IE) carries a high risk of postoperative mortality. Most complications are linked to uncontrolled sepsis and inflammatory processes. Cytokine haemoadsorption is..
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Jan 1, 1970
Pre-operative level of FGF23…
Abstract Background Early detection of acute kidney injury (AKI) after cardiac surgery has improved recently with the discovery and validation of novel urinary biomarkers. However, objective tools to predict the..
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Jan 1, 1970
Anticoagulation with VADs and…
Abstract The evolution of devices for mechanical circulatory support (MCS), including ventricular assist devices (VADs) for patients with heart failure and extracorporeal membrane oxygenation (ECMO) for patients with acute cardiac..
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Jan 1, 1970
Addressing the challenges of…
Abstract Introduction/Aim: The patient’s condition and high-risk nature of extracorporeal membrane oxygenation (ECMO) therapy force clinical services to ensure clinicians are properly trained and always ready to deal effectively with..
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Jan 1, 1970
A Table Mounted Cardiopulmonary…
Abstract Systemic inflammatory response and are prominent factors associated with and result in increased morbidity and mortality in children. Miniaturized systems have evolved to decrease such effects and restrict use of blood..
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Jan 1, 1970
Albumin priming improves the…
Abstract The desired use of the HPH Jr. is optimal due to the low priming volume; however, the lower rate of volume removal necessitates utilization of a larger hemofilter. Larger..
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Jan 1, 1970
A red cell preservation…
Summary Background Blood transfusion has well‐documented adverse effects. As part of a blood conservation initiative at our center, we began routine use of cell saver for all congenital heart surgery..
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Jan 1, 1970
Comparison of Ringer’s Lactate…
Abstract Introduction A wide range of acid base fluctuations are seen during Cardiopulmonary bypass (CPB) and the development of metabolic acidosis is well recognized. We conducted a study tocompare the..
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Jan 1, 1970
Impact of MELD score…
Abstract Background The outcome of open-heart surgery for patients with liver cirrhosis (LC) varies widely, indicating multifactorial influences on liver injury after cardiopulmonary bypass (CPB). Methods This observational single center..
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Jan 1, 1970
Procalcitonin to stop antibiotics…
Abstract Introduction and objective Children admitted to the pediatric intensive care unit after cardiovascular surgery usually require treatment with antibiotics due to suspicion of infection. The aim of this study..
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Jan 1, 1970
Editorial: Improving Extracorporeal Life…
Abstract Extracorporeal life support (ECLS, also known as extracorporeal membrane oxygenation or ECMO) emerged in the 1970s as a potentially useful life-support therapy for refractory cardiac or respiratory failure in..
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Jan 1, 1970
The correlation of post-operative…
Abstract Background and objective Acute kidney injury (AKI) following cardiac surgery with cardiopulmonary bypass (CPB) is polyethiological clinical syndrome. During CPB haemodilution develops, which is useful in reducing the risk..
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Jan 1, 1970
Microcirculatory perfusion disturbances following…
Abstract Background Endothelial hyperpermeability following cardiopulmonary bypass (CPB) contributes to microcirculatory perfusion disturbances and postoperative complications after cardiac surgery. We investigated the postoperative course of renal and pulmonary endothelial barrier..
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Jan 1, 1970
Factors involved in initiation…
Abstract Congenital heart disease (CHD) often requires surgical intervention, and is sometimes associated with life-threatening post-operative complications. We have investigated some factors of the innate immune system involved in the..
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Jan 1, 1970
Comparison of intestinal ischemia…
Abstract Acute mesenteric ischemia (AMI), one of the gastrointestinal system complications, which occurs following cardiac surgery, is challenged in the literature with a diminished incidence of AMI by heart surgery..
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Jan 1, 1970
Switching to Centrifugal Pumps…
Abstract Recent advances in ECLS technology have led to the adoption of centrifugal pumps for the majority of patients worldwide. Despite several advantages of centrifugal pumps, they remain controversial because..
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Jan 1, 1970
Membrane Lung and Blood…
Trends From 2002 to 2017 Extracorporeal life support (ECLS) has grown in its application since its first clinical description in the 1970s. The technology has been used to support a..
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Jan 1, 1970
Comparison of temporary ventricular…
Abstract OBJECTIVES Post-cardiotomy cardiogenic shock (PCCS) results in substantial morbidity and mortality, whereas refractory cases require mechanical circulatory support (MCS). The aim of the study was to compare extracorporeal membrane..
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Jan 1, 1970
Audit of transfusion of…
Abstract Background: Cardiac surgery is associated with peri-operative bleeding, which may result in the need for blood transfusion, particularly in paediatric congenital cardiac surgery on cardiopulmonary bypass (CPB). There is..
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Jan 1, 1970
Functional Performance of Different…
Abstract Objective: Hemodilution is a concern in cardiopulmonary bypass (CPB). Using a smaller dual tubing rather than a single larger inner diameter (ID) tubing in the venous limb to decrease..
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Jan 1, 1970
Comparison of the Coagulation…
Abstract OctaplasLG is indicated for use in patients undergoing cardiac surgery who require replacement of multiple clotting factors. The use of OctaplasLG over single-donor fresh frozen plasma (FFP) may have..
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Jan 1, 1970
Urinary hypoxia: an intraoperative…
Abstract Background Acute kidney injury (AKI) is common after cardiac surgery and profoundly affects postoperative mortality and morbidity. There are no validated methods to assess risk of AKI intraoperatively. Methods..
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Jan 1, 1970
Predictors of Poor Outcomes…
Abstract Background: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) provides respiratory and hemodynamic support to pediatric patients in severe cardiac failure. We aim to identify risk factors associated with poorer outcomes in..
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Jan 1, 1970
The use of acute…
Abstract Background Acute normovolemic hemodilution (ANH) is considered safe and effective in decreasing perioperative transfusion in paediatric populations undergoing high blood‐loss surgeries. We determined the association between ANH and the..
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Jan 1, 1970
Better platelet function, less…
Abstract Introduction: Residual pump blood from the cardiopulmonary bypass (CPB) circuit is often collected into an infusion bag (IB) and re-transfused. An alternative is to chase the residual blood into..
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Jan 1, 1970
Optimizing patient care and…
Abstract Pediatric cardiovascular services are responding to the dynamic changes in the medical environment, including the business of medicine. The opportunity to advance our pediatric cardiology field through collaboration is..
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Jan 1, 1970
Cerebral near‐infrared spectroscopy (NIRS)…
Background Various techniques have been employed for the early detection of perioperative cerebral ischaemia and hypoxia. Cerebral near‐infrared spectroscopy (NIRS) is increasingly used in this clinical scenario to monitor brain..
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Jan 1, 1970
Influence of the type…
Abstract Background In children with congenital heart disease (CHD), altered pulmonary circulation compromises gas exchange. Moreover, pulmonary dysfunction is a complication of cardiac surgery with cardiopulmonary bypass (CPB). No data..
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Jan 1, 1970
Plasma levels of alarmin…
ABSTRACT Background Early onset of lung injury is considerable common after cardiac surgery and is associated with increasing in morbidity and mortality, but current clinical predictors for the occurrence of..
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Jan 1, 1970
An Absorbable Hydrogel Spray…
Abstract Background Adhesions encountered during reoperative cardiac surgery can prolong operative time and increase operative risk. The purpose of this clinical study was to investigate the antiadhesion property of a..
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Jan 1, 1970
Red Blood Cell Exosome…
Abstract Objective Hemolysis, characterized by formation of free hemoglobin (Hb), occurs in patients undergoing cardiopulmonary bypass (CPB). However, there is no study of the dynamic changes in red blood cell..
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Jan 1, 1970
Dose Estimation for Bivalirudin…
Abstract Aim A typical adult based bivalirudin regimen during cardiopulmonary bypass uses a loading dose of 1 mg.kg‐1 and a circuit prime (volume L x 13 mg) with a subsequent intravenous..
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Jan 1, 1970
Cardiopulmonary Bypass-Induced Coagulopathy in…
Abstract Introduction Paediatric patients are particularly prone to cardiopulmonary bypass (CPB)‐induced coagulopathy mainly due to haemodilution, consumption of coagulation factors and hypothermia. The aim of the present study was to..
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Jan 1, 1970
Successful use of an…
Abstract A morbidly obese middle aged woman in her 40’s presented to another hospital with methicillin resistant staphylococcus aureus pneumonia and subsequently developed severe acute respiratory distress syndrome. Her oxygenation..
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Jan 1, 1970
The Norwood Stage 1…
Abstract Hypoplastic left heart syndrome (HLHS) is a rare and severe congenital cardiac defect. Approximately 1000 infants are born with HLHS in the United States every year. Healthcare collaboratives over..
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Jan 1, 1970
Prediction of Bleeding in…
Abstract Bleeding caused by coagulopathy is common in children undergoing cardiac surgery and causes adverse outcomes. Coagulation testing assists selection of treatments to stop bleeding but has an uncertain role..
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Jan 1, 1970
Use of the Hypotension…
Abstract Objective The hypotension prediction index (HPI) is a novel parameter developed by Edwards Lifesciences (Irvine, CA) that is obtained through an algorithm based on arterial pressure waveform characteristics. Past..
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Jan 1, 1970
ECMELLA: Successful Rescue Cardiopulmonary…
Abstract Background Cardiogenic shock is the main cause of death in hospitalized patients with acute coronary syndromes, with a high mortality rate. The management of graft thrombosis after coronary artery..
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Jan 1, 1970
Preoperative Endothelial Dysfunction in…
Abstract Background Cardiac surgery is known to induce acute endothelial dysfunction, which may be central to the pathophysiology of postoperative complications. Preoperative endothelial dysfunction could also be implicated in the..
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Jan 1, 1970
Management of Congenital Cardiac…
Abstract The new coronavirus infection, which was first seen in China in late December, 2019 and eventually became a worldwide pandemic, poses a serious threat to public health. After a..
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Jan 1, 1970
Preoperative extracorporeal membrane oxygenation…
Background The efficacy of extracorporeal membrane oxygenation (ECMO) in bridging children with unrepaired heart defects to a definitive or palliative surgical procedure has been rarely reported. The goal of this..
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Jan 1, 1970
Continuous Monitoring of Cerebral…
The use of extracorporeal membrane oxygenation has had a positive impact on the outcomes after lung transplantation. Extracorporeal membrane oxygenation has a role in all phases of lung transplantation—preoperative, intraoperative,..
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Jan 1, 1970
Continuous Monitoring of Cerebral…
Objective Cerebral autoregulation (CA) impairment may pose a risk factor for neurological complications among children supported by extracorporeal membrane oxygenation (ECMO). Our first objective was to investigate the feasibility of..
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Jan 1, 1970
Dual Carbon Dioxide Capture…
Abstract Extracorporeal CO2 removal is a highly promising support therapy for patients with hypercapnic respiratory failure but whose clinical implementation and patient benefit is hampered by high cost and highly specialized..
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Jan 1, 1970
Measures of Anticoagulation and…
Abstract Introduction: Pediatric cardiac Extracorporeal Membrane Oxygenation (ECMO) is effective, however, bleeding and clotting issues continue to cause significant morbidity and mortality. The objective of this study was to assess..
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Jan 1, 1970
The Great Ormond Street…
Traditionally, ABO-incompatible heart transplantation was accomplished using a plasma exchange technique to remove recipient plasma containing donor-incompatible anti-A/B isohaemagglutinins. However, this technique exposed patients to large volumes of allogeneic blood..
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Jan 1, 1970
Successful Use of An…
Abstract A morbidly obese middle aged woman in her 40's presented to another hospital with and subsequently developed severe . Her oxygenation demonstrated no improvement with low ventilation, paralysis, or prostagladin therapy. She..
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Jan 1, 1970
Impact of Corticosteroids on…
Abstract Background Corticosteroids (CS) suppress the inflammatory response to cardiopulmonary bypass in children undergoing cardiac surgery. What is less clear is the impact of CS on the postoperative course. Methods..
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Jan 1, 1970
Efficacy and Safety of…
Background Although corticosteroid prophylaxis in adult cardiac surgery has been studied extensively for 40 years, its role remains controversial, and the optimal dose remains uncertain. The objective of this meta-analysis..
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Jan 1, 1970
Pediatric Intensive Care Preparedness…
Abstract Since the beginning of the pandemic Coronavirus Disease 2019 (COVID-19), calls were made for informed allocation of costly, limited health care resources such as extracorporeal membrane oxygenation (ECMO). At..
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Jan 1, 1970
Evaluation of Recirculation During…
Abstract Recirculation in venovenous extracorporeal membrane oxygenation (VV ECMO) leads to reduction in gas transfer efficiency. Studies of the factors contributing have been performed using in vivo studies and computational..
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Jan 1, 1970
American Society of ExtraCorporeal…
Abstract The development of standards and guidelines by professional societies offers clinicians guidance toward providing evidence-based care. The ultimate goals of standards and guidelines are to standardize care and improve..
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Jan 1, 1970
Outcomes of Multiple Runs…
Abstract Objective When patients deteriorate after decannulation from extracorporeal membrane oxygenation (ECMO), a second run of extracorporeal support may be considered. However, repeat cannulation can be difficult and poor outcomes..
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Jan 1, 1970
Investigation of Myocardial Protection…
Abstract Many measures have been proposed for myocardial protection in pediatric congenital heart surgeries, but little data is available for China. This study investigates myocardial protection strategies in pediatric cardiopulmonary..
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Jan 1, 1970
Practical Management of ECPELLA
Abstract Veno-arterial extracorporeal membrane oxygenation (ECMO) is a strong mechanical circulatory device for patients with hemodynamic deterioration due to cardiogenic shock, but its drawback is an increase in left ventricular..
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Jan 1, 1970
Sustained Total All-Region (STAR)…
Abstract Early iterations of the Norwood procedure used aortic cross-clamping, myocardial arrest, and, sometimes, deep hypothermic circulatory arrest. The resulting hypothermia and prolonged ischemia caused frequent cardiac, neurologic, renal, and..
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Jan 1, 1970
Conventional Ultrafiltration During Elective…
Abstract Objective Conventional ultrafiltration (CUF) during cardiopulmonary bypass (CPB) serves to hemoconcentrate blood volume to avoid allogeneic blood transfusions. Previous studies have determined CUF volumes as a continuous variable are..
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Jan 1, 1970
Cardiopulmonary Bypass Duration and…
A Retrospective Cohort Study Purpose The purpose of our study was to investigate the association between cardiopulmonary bypass (CPB) duration and the incidence of pressure injuries (PIs) in patients undergoing..
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Jan 1, 1970
Goal-Directed Perfusion to Reduce…
Abstract Introduction Cardiac surgery-associated acute kidney injury (CS-AKI) occurs in up to 40%~60% of paediatric patients and increases postoperative morbidity and mortality. A goal-directed perfusion (GDP) strategy aimed at maintaining..
