Abstract Optimal oxygen target levels for critically ill patients have been discussed for decades and very low but also high PaO2-levels were both associated with higher mortality [, ]. In..
Read MoreAbstract Early rehabilitation during venovenous extracorporeal membrane oxygenation used as a bridge to recovery (VV ECMO–BTR) may help preserve functional capacity. We retrospectively analyzed 153 adults supported with VV ECMO–BTR..
Read MoreAbstract Background Veno-venous extracorporeal membrane oxygenation (VV ECMO) is an advanced therapy for patients with respiratory failure refractory to conventional management. Volume overload and elevated lactate levels have been associated..
Read MoreAbstract Background Decannulation from venovenous extracorporeal membrane oxygenation (ECMO) at the earliest safe opportunity would be expected to improve patient outcomes. Currently, the manner in which clinicians liberate patients from..
Read MoreAbstract Background The expanding availability of venovenous extracorporeal membrane oxygenation (ECMO) and the increasing frequency of prolonged ECMO runs challenge standard definitions of center experience based solely on patient counts...
Read MoreAbstract Awake extracorporeal membrane oxygenation (aECMO) has emerged as a strategy to minimise physical and neurocognitive complications of a prolonged intensive care admission. However, the safety and implementation in critically..
Read MoreAbstract Background The efficiency of venovenous extracorporeal membrane oxygenation (VV ECMO) may be influenced by cannula configuration, potentially affecting oxygenation and the ability to apply ultra-protective ventilation in severe ARDS...
Read MoreAbstract Purpose: Recirculation is a critical issue in veno-venous extracorporeal membrane oxygenation (VV ECMO). We propose a novel method for estimating the recirculation ratio using temporary sweep-gas control. Methods: A circuit simulating..
Read MoreAbstract Recirculation reduces the efficiency of venovenous extracorporeal membrane oxygenation (V-V ECMO), but patient-specific determinants of recirculation and the feasibility of recirculation-guided flow adjustment are not well defined. In this..
Read MoreAbstract Background The clinical impact of early spontaneous breathing during veno-venous extracorporeal membrane oxygenation (VV ECMO) for acute respiratory distress syndrome (ARDS) is unclear, balancing potential benefits (reducing sedation and..
Read MoreAbstract For pregnant patients with severe coronavirus disease 2019 (COVID-19) requiring veno-venous (V-V) extracorporeal membrane oxygenation (ECMO), the ideal timing of delivery is uncertain, particularly when complicated by cardiogenic shock...
Read MoreAbstract Introduction Standard anticoagulation protocols for patients with trauma-related acute respiratory distress syndrome (TR-ARDS) undergoing venovenous extracorporeal membrane oxygenation (VV-ECMO) are often inapplicable due to high bleeding risks. This study..
Read MoreAbstract Extracorporeal life support (ECLS) components designed to reduce clot formation have been developed, but thrombosis remains a significant challenge, requiring systemic anticoagulation. To address this, we evaluated a nitric..
Read MoreAbstract Veno-venous (VV) extracorporeal membrane oxygenation (ECMO) has many limitations, including patient comfort and, oftentimes, mobility issues. Veno-pulmonary (VP) ECMO offers respiratory support without recirculation and right heart support. For..
Read MoreAbstract Background Use of venoarterial (VA) extracorporeal membrane oxygenation (ECMO) in the setting of type A aortic dissection (TAAD) has been described in the literature as salvage therapy, with morbid..
Read MoreAbstract Background Although sedation is commonly used in patients undergoing venovenous extracorporeal membrane oxygenation (V-V ECMO), the use of volatile anesthetics is less frequent, and there is limited data on..
Read MoreAbstract Venovenous extracorporeal membrane oxygenation (VV ECMO) is a potentially lifesaving yet resource-intensive organ support option for patients with very severe respiratory failure refractory to optimized conventional management. Mortality remains..
Read MoreAbstract Background In adult patients receiving veno-venous Extracorporeal Membrane Oxygenation (VV ECMO), cardiovascular performance plays a critical role in determining oxygen delivery, organ perfusion and safe titration of extracorporeal support...
Read MoreAbstract Background: Lactic alkalosis, defined as an increase in circulating lactate in the setting of elevated extracellular pH, has been described in both in vivo and in vitro settings, often..
Read MoreAbstract Capnometry is a cost-efficient method of monitoring carbon dioxide (CO2) in healthcare settings, especially during mechanical ventilation and cardiopulmonary bypass. However, the utility of capnometers for studying CO2 elimination in..
Read MoreAbstract Background Chronic obstructive pulmonary disease (COPD) is the most prevalent chronic end stage lung disease. There are few long-term treatment options for end stage COPD due to donor lung..
Read MoreAbstract When critical illness is further complicated by severe respiratory failure, such as in cases of acute respiratory distress syndrome (ARDS) requiring veno-venous extracorporeal membrane oxygenation (VV-ECMO), patients may be..
Read MoreAbstract Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is a complex and invasive intervention used increasingly in the management of severe respiratory failure. Once established, the management of prolonged V-V ECMO..
Read MoreAbstract Differential oxygenation may complicate extracorporeal cardiopulmonary resuscitation (ECPR) either due to the initial pathology or subsequent lung injury. The dual circulation phenomenon inherent to peripheral venoarterial extracorporeal membrane oxygenation..
Read MoreAbstract Introduction Veno-venous extracorporeal membrane oxygenation (VV-ECMO) supports oxygenation and carbon dioxide (CO2) clearance in the short- or mid-term, and is traditionally utilized in severe, refractory respiratory failure. There is..
Read MoreAbstract Obesity poses technical challenges during veno-venous extracorporeal membrane oxygenation (VV-ECMO) cannulation because of thick subcutaneous tissue and increased insertion resistance. While patient-related factors are well recognized, the impact of..
Read MoreAbstract Importance Venovenous extracorporeal membrane oxygenation (VV ECMO) is a resource-intensive, life-sustaining technology to support patients with severe refractory respiratory failure. Its precise indications and contraindications are not standardized, and expert..
Read MoreAbstract Objectives In complex airway surgery and high-risk rigid bronchoscopy, conventional ventilation may be unsafe or impossible. We report our experience using veno-venous extracorporeal membrane oxygenation (VV-ECMO) as respiratory support...
Read MoreAbstract We aim to provide evidence-based clinical practice guidelines for the use of VV ECMO in adult patients across Australia and New Zealand. Developed by a multidisciplinary panel of clinicians..
Read MoreAbstract Background Patients with severe respiratory failure frequently suffer from concomitant haemodynamic compromise. By correcting respiratory acidosis and permitting reduced mechanical ventilation pressures, venovenous extracorporeal membrane oxygenation (V-V ECMO) may..
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