Tags Archives: Citrate

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Impact of Transfused Citrate on Pathophysiology in Massive Transfusion

Abstract OBJECTIVES:  This narrative review article seeks to highlight the effects of citrate on physiology during massive transfusion of the bleeding patient. DATA SOURCES:  A limited library of curated articles..

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The effects of differing anticoagulant regimes on blood quality after cell salvage in coronary artery bypass grafting (CABG): a pilot…

Abstract Background Cell salvage reduces allogenic blood transfusion requirements in surgery. We present a pilot study exploring the impact of anticoagulant choice, citrate or heparin, on the quality of cell..

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Citrate does not change viscoelastic haemostatic assays after cardiopulmonary bypass

Abstract Context: Viscoelastic hemostatic assays (VHA) are commonly used to identify specific cellular and humoral causes for bleeding in cardiac surgery patients. Cardiopulmonary bypass (CPB) alterations to coagulation are observable on..

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Citrate pathophysiology and metabolism

Abstract By chelating ionized  allows  circuit  without a bleeding risk for the patient. Citrate anticoagulation is also associated with a reduced activation of  and platelets. Citrate clearance by  (Krebs cycle) is not modified by renal..

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