Abstract OBJECTIVES: This narrative review article seeks to highlight the effects of citrate on physiology during massive transfusion of the bleeding patient. DATA SOURCES: A limited library of curated articles..
Read MoreAbstract Background Cell salvage reduces allogenic blood transfusion requirements in surgery. We present a pilot study exploring the impact of anticoagulant choice, citrate or heparin, on the quality of cell..
Read MoreAbstract Context: Viscoelastic hemostatic assays (VHA) are commonly used to identify specific cellular and humoral causes for bleeding in cardiac surgery patients. Cardiopulmonary bypass (CPB) alterations to coagulation are observable on..
Read MoreAbstract By chelating ionized allows circuit without a bleeding risk for the patient. Citrate anticoagulation is also associated with a reduced activation of and platelets. Citrate clearance by (Krebs cycle) is not modified by renal..
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