{"id":408,"date":"2024-12-31T17:19:55","date_gmt":"2024-12-31T17:19:55","guid":{"rendered":"https:\/\/perfusfind.com\/ic\/?p=408"},"modified":"2024-12-31T17:19:55","modified_gmt":"2024-12-31T17:19:55","slug":"fever-following-extracorporeal-membrane-oxygenation-decannulation-infection-thrombosis-or-just-physiology","status":"publish","type":"post","link":"https:\/\/perfusfind.com\/ic\/index.php\/2024\/12\/31\/fever-following-extracorporeal-membrane-oxygenation-decannulation-infection-thrombosis-or-just-physiology\/","title":{"rendered":"Fever following extracorporeal membrane oxygenation decannulation: Infection, thrombosis or just physiology?"},"content":{"rendered":"<h2 class=\"section-title u-h4 u-margin-l-top u-margin-xs-bottom\">Abstract<\/h2>\n<p>&nbsp;<\/p>\n<div id=\"as0005\">\n<h3 id=\"st0010\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">Purpose<\/h3>\n<div id=\"sp0050\" class=\"u-margin-s-bottom\">Fever is frequent after extracorporeal membrane oxygenation (ECMO) decannulation. We aimed to evaluate the incidence of post-decannulation fever and describe its causes.<\/div>\n<\/div>\n<div id=\"as0010\">\n<h3 id=\"st0015\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">Methods<\/h3>\n<div id=\"sp0055\" class=\"u-margin-s-bottom\">Adult ECMO patients who were successfully weaned from ECMO were retrospectively included. Minimal and maximal core temperatures were collected daily for each patient from 48\u00a0h before decannulation up to 5\u00a0days after. Patients were grouped according to the cause of fever (infection, thrombosis, or no evident cause) and compared. Plasma cytokine profile was obtained, each day from decannulation to 5\u00a0days after for 20 patients.<\/div>\n<\/div>\n<div id=\"as0015\">\n<h3 id=\"st0020\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">Results<\/h3>\n<div id=\"sp0060\" class=\"u-margin-s-bottom\">Between January 2021 and December 2022, 123 patients successfully weaned from ECMO were included. Post-decannulation fever occurred in 54 patients (44\u00a0%). It was associated with an infection in 39 patients (72\u00a0%) and with a thrombosis in 6 patients (11\u00a0%), and no cause was identified in the remaining 9 (17\u00a0%). Prolonged ECMO duration, extended ICU length-of-stay, diabetes and vascular comorbidities were significantly associated with a higher risk of infection. Finally, the pro-inflammatory cytokine profiles did not differ between febrile and afebrile patients.<\/div>\n<\/div>\n<div id=\"as0020\">\n<h3 id=\"st0025\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">Conclusion<\/h3>\n<div id=\"sp0065\" class=\"u-margin-s-bottom\">Post-decannulation fever was common, and was mainly due to infections or thrombosis. Fever should therefore not be considered as a benign inflammatory reaction until proven otherwise.<\/div>\n<div><\/div>\n<\/div>\n<div><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0883944124004325?via%3Dihub=&amp;utm_source=substack&amp;utm_medium=email\"><strong>ACCESS FULL ARTICLE HERE<\/strong><\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Abstract &nbsp; Purpose Fever is frequent after extracorporeal membrane oxygenation (ECMO) decannulation. We aimed to evaluate the incidence of post-decannulation fever and describe its causes. Methods Adult ECMO patients who were successfully weaned from ECMO were retrospectively included. Minimal and maximal core temperatures were collected daily for each patient from 48\u00a0h before decannulation up to [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":344,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[3],"tags":[16,121,120],"class_list":["post-408","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-circulatory","tag-ecmo","tag-ecmo-decannulation","tag-fever"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Fever following extracorporeal membrane oxygenation decannulation: Infection, thrombosis or just physiology? - Perfusfind Intensive Care<\/title>\n<meta name=\"description\" content=\"Fever is frequent after extracorporeal membrane oxygenation (ECMO) decannulation. 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We aimed to evaluate the incidence of post-decannulation fever and describe its causes. Methods Adult ECMO patients who were successfully weaned from ECMO were retrospectively included. 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