{"id":227,"date":"2024-12-02T15:42:20","date_gmt":"2024-12-02T15:42:20","guid":{"rendered":"https:\/\/perfusfind.com\/ic\/?p=227"},"modified":"2024-12-02T15:42:20","modified_gmt":"2024-12-02T15:42:20","slug":"investigating-computational-models-for-diagnosis-and-prognosis-of-sepsis-based-on-clinical-parameters-opportunities-challenges-and-future-research-directions","status":"publish","type":"post","link":"https:\/\/perfusfind.com\/ic\/index.php\/2024\/12\/02\/investigating-computational-models-for-diagnosis-and-prognosis-of-sepsis-based-on-clinical-parameters-opportunities-challenges-and-future-research-directions\/","title":{"rendered":"Investigating computational models for diagnosis and prognosis of sepsis based on clinical parameters: Opportunities, challenges, and future research directions"},"content":{"rendered":"<h2>&nbsp;<\/h2>\n<h2 id=\"Abs1\" class=\"c-article-section__title js-section-title js-c-reading-companion-sections-item\">Abstract<\/h2>\n<div id=\"abstracts\" class=\"Abstracts u-font-serif\">\n<div id=\"abs0001\" class=\"abstract author\">\n<div id=\"abss0001\">\n<div id=\"spara008\" class=\"u-margin-s-bottom\">This study investigates the use of computational frameworks for&nbsp;<a class=\"topic-link\" title=\"Learn more about sepsis from ScienceDirect's AI-generated Topic Pages\" href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/sepsis\">sepsis<\/a>. We consider two dimensions for investigation \u2013 early diagnosis of sepsis (EDS) and mortality prediction rate for sepsis patients (MPS). We concentrate on the clinical parameters on which sepsis diagnosis and prognosis are currently done, including customized treatment plans based on historical data of the patient. We identify the most notable literature that uses computational models to address EDS and MPS based on those clinical parameters. In addition to the review of the computational models built upon the clinical parameters, we also provide details regarding the popular publicly available data sources. We provide brief reviews for each model in terms of prior art and present an analysis of their results, as claimed by the respective authors. With respect to the use of machine learning models, we have provided avenues for model analysis in terms of model selection, model validation, model interpretation, and model comparison. We further present the challenges and limitations of the use of computational models, providing future research directions. This study intends to serve as a benchmark for first-hand impressions on the use of computational models for EDS and MPS of sepsis, along with the details regarding which model has been the most promising to date.<\/div>\n<div class=\"u-margin-s-bottom\">We have provided details regarding all the ML models that have been used to date for EDS and MPS of sepsis.<\/div>\n<div>&nbsp;<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"Abs1-content\" class=\"c-article-section__content\">\n<p><a class=\"fasc-button fasc-size-large fasc-type-flat fasc-rounded-medium fasc-ico-before dashicons-format-aside\" style=\"background-color: #b2b5ff; color: #000000;\" target=\"_blank\" rel=\"noopener\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2667100X24000744\">Read the full text<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; Abstract This study investigates the use of computational frameworks for&nbsp;sepsis. We consider two dimensions for investigation \u2013 early diagnosis of sepsis (EDS) and mortality prediction rate for sepsis patients (MPS). We concentrate on the clinical parameters on which sepsis diagnosis and prognosis are currently done, including customized treatment plans based on historical data of [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":216,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[5],"tags":[27,28],"class_list":["post-227","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sepsis","tag-diagnosis","tag-early-diagnosis-of-sepsis-eds"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Investigating computational models for diagnosis and prognosis of sepsis based on clinical parameters: Opportunities, challenges, and future research directions - Perfusfind Intensive Care<\/title>\n<meta name=\"description\" content=\"This study intends to serve as a benchmark for first-hand impressions on the use of computational models for EDS and MPS of sepsis, along with the details regarding which model has been the most 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href=\"https:\/\/perfusfind.com\/ic\/index.php\/category\/sepsis\/\" rel=\"category tag\">Sepsis<\/a>","rttpg_excerpt":"&nbsp; Abstract This study investigates the use of computational frameworks for&nbsp;sepsis. We consider two dimensions for investigation \u2013 early diagnosis of sepsis (EDS) and mortality prediction rate for sepsis patients (MPS). We concentrate on the clinical parameters on which sepsis diagnosis and prognosis are currently done, including customized treatment plans based on historical data of&hellip;","_links":{"self":[{"href":"https:\/\/perfusfind.com\/ic\/index.php\/wp-json\/wp\/v2\/posts\/227","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/perfusfind.com\/ic\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/perfusfind.com\/ic\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/perfusfind.com\/ic\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/perfusfind.com\/ic\/index.php\/wp-json\/wp\/v2\/comments?post=227"}],"version-history":[{"count":1,"href":"https:\/\/perfusfind.com\/ic\/index.php\/wp-json\/wp\/v2\/posts\/227\/revisions"}],"predecessor-version":[{"id":231,"href":"https:\/\/perfusfind.com\/ic\/index.php\/wp-json\/wp\/v2\/posts\/227\/revisions\/231"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/perfusfind.com\/ic\/index.php\/wp-json\/wp\/v2\/media\/216"}],"wp:attachment":[{"href":"https:\/\/perfusfind.com\/ic\/index.php\/wp-json\/wp\/v2\/media?parent=227"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/perfusfind.com\/ic\/index.php\/wp-json\/wp\/v2\/categories?post=227"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/perfusfind.com\/ic\/index.php\/wp-json\/wp\/v2\/tags?post=227"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}