{"id":1371,"date":"2026-03-15T03:36:50","date_gmt":"2026-03-15T03:36:50","guid":{"rendered":"https:\/\/perfusfind.com\/ic\/?p=1371"},"modified":"2026-03-15T03:36:50","modified_gmt":"2026-03-15T03:36:50","slug":"healthcare-costs-after-sepsis-a-systematic-review","status":"publish","type":"post","link":"https:\/\/perfusfind.com\/ic\/index.php\/2026\/03\/15\/healthcare-costs-after-sepsis-a-systematic-review\/","title":{"rendered":"Healthcare costs after sepsis: a systematic review"},"content":{"rendered":"

Abstract:<\/strong><\/p>\n

This systematic review<\/strong> of 23 studies (2000\u20132025) examined healthcare costs among adult sepsis survivors in developed nations<\/strong>. While in-hospital sepsis costs are well described, this review reveals that post-discharge healthcare costs remain high for years<\/strong>. Median one-year cost per survivor<\/strong> was $28,719 (IQR $21,715)<\/strong>, with second-year costs still averaging $22,460 (IQR $14,407)<\/strong>. Median cost of a readmission was $20,320 (IQR $4,889)<\/strong>. In studies with comparators, sepsis survivors consistently accrued higher costs than non-sepsis survivors.<\/p>\n

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Key Insights<\/h3>\n
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  1. Scope:<\/strong> 23 cohort studies, sample sizes up to 2.5M patients, across US, Canada, Germany, France, Latvia, Australia.<\/li>\n
  2. Persistence of costs:<\/strong> High expenditures persisted beyond 5 years, especially from rehospitalizations and long-term care.<\/li>\n
  3. Drivers:<\/strong> Readmissions, outpatient visits, medications, rehabilitation, and chronic care services.<\/li>\n
  4. Comparisons:<\/strong> Sepsis survivors had significantly higher costs than matched non-sepsis controls in 6 of 7 comparator studies.<\/li>\n
  5. High-cost users:<\/strong> Sepsis survivors disproportionately became top 5% healthcare spenders<\/strong>, consuming major system resources.<\/li>\n
  6. Policy relevance:<\/strong> Supports WHA resolution 70.7<\/strong> and Berlin Declaration<\/strong> to reduce long-term sepsis burden.<\/li>\n<\/ol>\n
    \n

    Why This Matters<\/h3>\n

    Sepsis is not only a leading killer but also a driver of chronic healthcare costs<\/strong>. Survivors face prolonged disability, readmissions, and high health service utilization. For policymakers, post-sepsis care planning is as critical as in-hospital management<\/strong>.<\/p>\n

    \n

    Conclusion<\/h3>\n

    Sepsis survivors generate sustained, high post-discharge costs<\/strong> that burden health systems for years. Strategies to reduce readmissions, improve rehabilitation, and prevent long-term complications are urgently needed.<\/p>\n

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    Take-Home for Clinicians<\/h3>\n